Gene Information

Name : hemC (Cag_1515)
Accession : YP_379813.1
Strain : Chlorobium chlorochromatii CaD3
Genome accession: NC_007514
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1988591 - 1989532 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAAAAAACAGCTTATTATCGGCACCCGCTCCAGCCCCCTTGCATTGTGGCAGGCAGAATTTACGAAAGCAGAGCTTTC
GAAGCATTATCCTGATATGGAAATCACCTTGAAGTTGGTGAAAACCACCGGTGATGTGCTGCTTGATTCGCCACTTTCTA
AAATTGGCGATATGGGGCTTTTTACGAAGGATATTGAAAAGCATTTGCTTGCTCGCGAAATTGACTTGGCGGTTCACAGT
CTTAAAGATGTGCCAACCAGCACGCCTGAGGGATTAATTATCACCTCGTTTACCGAGCGTGAGGATACCCGCGACGTTAT
TATTTCAAAAGGTGGCGTTAAGCTGAAAGATTTGCCTCCTAATGCTCGTATGGCAACCAGCTCGCTTCGTCGTATGTCGC
AGTTGCTCAGTGTTCGCCCTGACCTTGATATTCGCGACATTCGTGGCAACCTCAACACTCGTTTCCAAAAGTTTGATGAT
GGCGAATTTGATGCCATGATGCTTGCTTACGCAGGTGTTTATCGCTTGAACTTTAGCGATCGCATCTCTGAAATTTTACC
GCACGACATGATGTTGCCAGCGGTTGGTCAAGGTGCGCTTGGTATTGAAACTCGTGTTGATGATGAGCAAACTCGTGAGA
TTGTGCGCATTCTTAACCACTCTACCACTGAGTATTGCTGCCGTGCAGAACGTGCATTGTTGCGCCATTTGCAAGGCGGA
TGCCAAATTCCAATTGGTGCTTATGCAACCTTCAGCAACGGTACCTTAAAGTTGTTGGCGTTTGTTGGCTCTGTTGATGG
AAAAACTGCGTTGCGTAACGAAATCACTAAAACGGGCTTAACCTCGCCAGAACAAGCTGAAGAGGCTGGTATTGCTTTAG
CTGAAGAGCTTTTAAAGCAAGGTGCGGATGCTATTTTGTCGCAAATTCGTAAAACTTGCTAA

Protein sequence :
MKKQLIIGTRSSPLALWQAEFTKAELSKHYPDMEITLKLVKTTGDVLLDSPLSKIGDMGLFTKDIEKHLLAREIDLAVHS
LKDVPTSTPEGLIITSFTEREDTRDVIISKGGVKLKDLPPNARMATSSLRRMSQLLSVRPDLDIRDIRGNLNTRFQKFDD
GEFDAMMLAYAGVYRLNFSDRISEILPHDMMLPAVGQGALGIETRVDDEQTREIVRILNHSTTEYCCRAERALLRHLQGG
CQIPIGAYATFSNGTLKLLAFVGSVDGKTALRNEITKTGLTSPEQAEEAGIALAEELLKQGADAILSQIRKTC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-59 50
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-59 50