Gene Information

Name : lysS (Cag_1176)
Accession : YP_379481.1
Strain : Chlorobium chlorochromatii CaD3
Genome accession: NC_007514
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1570430 - 1571965 bp
Length : 1536 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGCAAAAAAATACTTCTCAGCCAACCAATACCAACGAACAAAGCAATCAACCATCTCTTAACGATCAAATTGTACGCCG
TATTGAAGAGCGCCAACATTTAATAGATTCTGGGATTAATCCATATCCTTGCTCATTTAATGTTACGCACCATTCAGCAA
CAATTTTGACTGAATTTCAAGATGAAGCCAAAACACCCGTTGCCGTTGCAGGACGCATTATGACCATTCGTAAAATGGGC
AAAGCTTCTTTTTTTAATGTGCAAGATTCAGCGGGTAGAATTCAAATTTATCTTAAAAAAGATGACGTAGGTGAAGCCGC
TTACAATATGTTTAAACTGCTTGATATTGGGGATATTGTTGGCGTTACAGGTTATACCTTTCGTACAAAAACGGGCGAAA
TTTCTATTCATGCCGAATCATTGGAATTATTAACAAAGTCGCTTCGCCCTATTCCAATTGCTAAAGAAAAAGAGGTTGAT
GGTGAAAAGGTTGTGTTTGATGCCTTTAGCGATAAAGAGTTGCGCTACCGTCAACGCTATGTTGACTTAATTGTAAATCC
CGAAGTGCGCGAAACATTTATTAAACGCACGGCGATTGTTGCTGCCATGCGTAACTTTTTTGCTCGCCACGGCTGGCTTG
AAGTTGAAACACCAATTCTACAACCCATTTATGGTGGAGCTGCTGCACGTCCATTTACTACGCATCACAATGCGCTCGAT
ATGCAGCTTTATTTGCGTATTGCAAATGAATTATATCTTAAGCGGCTGATTGTTGGCGGATTTGATGGCGTTTTTGAGTT
TGCAAAAGATTTTAGAAATGAAGGTATTGATCGCTTTCATAATCCTGAGTTTACCCAAGTTGAGCTGTATGTTGCTTACA
AAGACTATAATTGGATGATGAACTTAGTGGAAGAGCTGATTTATACCACCGCAATGGAGGTCAACAAAAGCGACACCACC
ACTTTTCTTGGGCACGAAATTAGCGTAAAGCCACCATTTCGTCGCCTTACCATTAGCGATGCTATTGCCGAATACACAGA
TAAAGATATTCGCAACAAATCGGAAGAAGAGCTTCGGAATATTGCAAAAGAACTTGGTTTAGAGCTTGATCCAAAAATCG
GCAATGGTAAAATTATAGATGAAATTTTTGGCGAATTTGTTGAACCGAAATTGATTCAGCCCACATTTATTACCGACTAC
CCAACTGAAATGTCGCCACTTGCAAAAGAACACGCTGCGCAACCCGGCATTGTAGAGCGCTTTGAATTAATTGTAGGTGG
CAAAGAGGTTTGTAACTCCTTCTCGGAACTAAACGATCCTGTTATTCAGCGCGAACGGCTTGAATCGCAAGCGAAGCTTC
GCCTGCGTGGCGACGAAGAGGCAATGGTGGTGGATGAAGATTTCCTTCGCGCTATTGAATACGGTATGCCACCATGCGCA
GGGCTTGGTGTTGGCATTGACCGCCTTGTTATGTTGCTTACGGGGCAAGAATCAATTCGTGATGTTATTTTCTTTCCGCA
TTTAAAGCCAGAGTAA

Protein sequence :
MQKNTSQPTNTNEQSNQPSLNDQIVRRIEERQHLIDSGINPYPCSFNVTHHSATILTEFQDEAKTPVAVAGRIMTIRKMG
KASFFNVQDSAGRIQIYLKKDDVGEAAYNMFKLLDIGDIVGVTGYTFRTKTGEISIHAESLELLTKSLRPIPIAKEKEVD
GEKVVFDAFSDKELRYRQRYVDLIVNPEVRETFIKRTAIVAAMRNFFARHGWLEVETPILQPIYGGAAARPFTTHHNALD
MQLYLRIANELYLKRLIVGGFDGVFEFAKDFRNEGIDRFHNPEFTQVELYVAYKDYNWMMNLVEELIYTTAMEVNKSDTT
TFLGHEISVKPPFRRLTISDAIAEYTDKDIRNKSEEELRNIAKELGLELDPKIGNGKIIDEIFGEFVEPKLIQPTFITDY
PTEMSPLAKEHAAQPGIVERFELIVGGKEVCNSFSELNDPVIQRERLESQAKLRLRGDEEAMVVDEDFLRAIEYGMPPCA
GLGVGIDRLVMLLTGQESIRDVIFFPHLKPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 6e-99 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_379481.1 lysyl-tRNA synthetase VFG1668 Protein 3e-99 45