Gene Information

Name : guaA (Syncc9902_0042)
Accession : YP_376060.1
Strain : Synechococcus sp. CC9902
Genome accession: NC_007513
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 39948 - 41534 bp
Length : 1587 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCCCAGCCCTCGTCCGACGGTCAGCGTCAGCCGGCCATCGTCATCCTCGACTTTGGTTCTCAATATTCCGAACTGAT
CGCCCGTCGTGTTCGAGAAACCGAGGTGTTTTCGGTGGTGATCGGATACAGCACTACGGCGGATGAGCTGCGTCGGATGG
CCCCGAAGGGAATCATCTTGAGTGGTGGACCGAGCTCGGTGTACGCAGAGCATGCACCGGTTTGTGATCCTGCGATATGG
GATCTCGGTATCCCGGTGTTGGGGGTTTGTTATGGCATGCAGCTGATGGTTCAGCAGCTGGGGGGTGCTGTTGAGGCGGC
CACTGGTAAGGCGGAATACGGCAAGGCTCCTTTGGAGGTGGATGACCCCACCGACCTGCTCAACAACGTGGAGAACGGTT
CCACCATGTGGATGAGCCATGGCGACTCGGTGAAGGCCTTGCCAGAGGGCTTCGTGCGTTTGGCCCACACTGCAAATACG
CCTGAAGCTGCGGTCGCCAATCTTGAGCGCAAGTTTTACGGCGTGCAGTTTCATCCAGAGGTGGTGCATTCCACCTGTGG
GATGGCTTTGATTCGCAATTTTGTGAATCACATATGTGGCTGTGAGCAGGATTGGACCACCAATGCCTTCATTGATGAAG
CGGTGGCTTTGGTGCGTGAACAGGTGGGACAAAAGCGGGTTTTGTTGGCTCTCTCTGGAGGGGTTGACTCCTCAACCCTC
GCTTTTCTGTTGAAAAAAGCGATTGGTGATCAGCTCACTTGCATGTTCATTGATCAGGGCTTTATGCGGAAAGGAGAGCC
TGAATTCTTGATGGAATTTTTTGATCAAAAATTCAACATTAATGTGGAATATATCAATGCACGTAAGCGCTTTATTGACA
AACTAAAAGGCATTACTGATCCGGAAGATAAACGCAAAATTATTGGCACGGAATTCATTCGAGTTTTTGAGGAAGAGAGC
AAGCGCCTCGGACCATTCGATTATTTGGCTCAGGGCACGCTCTACCCCGATGTGATTGAAAGTGCAGGTACCAACGTTGA
TCCGAAAACGGGTGAGCGTGTGGCCGTAAAGATCAAGAGCCACCACAATGTTGGCGGCTTGCCAAAAGATTTGCGATTCA
AGTTAGTAGAACCCCTGCGCAAATTGTTTAAAGATGAAGTGCGCAAAGTGGGTCGCAACTTGGGGCTGCCAGAGGAGATT
GTGAGGCGTCATCCCTTTCCTGGGCCTGGGTTGGCGATTCGAATCCTTGGCGAAGTGACGGATGAAAAGCTCAACTGCCT
CCGTGATGCTGATTTGATCGTCCGGGAGGAGATTCGTGATGCCGGGCTCTATCACGACATATGGCAGGCCTTCGCTGTTT
TATTGCCTGTTCGTTCTGTGGGGGTGATGGGTGATCAGCGCACCTATGCTTGGCCGATTGTGCTTCGTTGTGTCTCTAGT
GAAGACGGAATGACGGCCGACTGGTCGCGTCTTCCTTACGACCTGATGGAGAGGATTTCCAATCGAATTGTCAACGAGGT
GAAAGGGGTGAACCGTGTAGTGATGGACATCACCAGCAAGCCTCCTGGCACAATTGAGTGGGAATAG

Protein sequence :
MSQPSSDGQRQPAIVILDFGSQYSELIARRVRETEVFSVVIGYSTTADELRRMAPKGIILSGGPSSVYAEHAPVCDPAIW
DLGIPVLGVCYGMQLMVQQLGGAVEAATGKAEYGKAPLEVDDPTDLLNNVENGSTMWMSHGDSVKALPEGFVRLAHTANT
PEAAVANLERKFYGVQFHPEVVHSTCGMALIRNFVNHICGCEQDWTTNAFIDEAVALVREQVGQKRVLLALSGGVDSSTL
AFLLKKAIGDQLTCMFIDQGFMRKGEPEFLMEFFDQKFNINVEYINARKRFIDKLKGITDPEDKRKIIGTEFIRVFEEES
KRLGPFDYLAQGTLYPDVIESAGTNVDPKTGERVAVKIKSHHNVGGLPKDLRFKLVEPLRKLFKDEVRKVGRNLGLPEEI
VRRHPFPGPGLAIRILGEVTDEKLNCLRDADLIVREEIRDAGLYHDIWQAFAVLLPVRSVGVMGDQRTYAWPIVLRCVSS
EDGMTADWSRLPYDLMERISNRIVNEVKGVNRVVMDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-135 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-142 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-141 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-141 54