Gene Information

Name : tpx (Plut_0730)
Accession : YP_374648.1
Strain : Chlorobium luteolum DSM 273
Genome accession: NC_007512
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 843689 - 844252 bp
Length : 564 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
TTGACAGACGGTTCGTTTCTCCTCGGAGTCTTTTTTTTTTTCAAACCAATCAATGATTTGTTTATGGCCACCATCACCCT
CAAGGGCAACCCTGTACACACCTCCGGAACCCTTCCGGCCGTCGGCACTGAAGCTCCTTTTTTCTGCCTCGTGAAAACCG
ATCTCAGTGAAGCCGGTCCTGCTGATTTTGCCGGACGCCGTATGGTGCTCAACATTTTTCCGAGTCTGGATACAGCAGTC
TGCGCTGCTTCCGTCAGGCGCTTCAACCAGGAAGCCGCAGCACTCGACAACACGGTCGTGCTCTGTATTTCAGCAGATCT
TCCCTTCGCCCACAACCGGTTCTGCGAGCTTGAGGGGCTGACGGATGTCATTGCGCTTTCCGTGTTCCGTTCCCCCGAGT
TCGGCCGCGATTATGGCGTGACCCTCACCGACGGACCGCTGAAGGGCCTGCTTTCACGAGCCGTGGTCGTAGTCGACGCA
GACGGACGTGTGGCATACAGCGAGCAGGTGCCCGAAATCGTGCAGGAACCCGACTACGCAGCAGCCCTCAAGGCACTGCA
GTGA

Protein sequence : 
MTDGSFLLGVFFFFKPINDLFMATITLKGNPVHTSGTLPAVGTEAPFFCLVKTDLSEAGPADFAGRRMVLNIFPSLDTAV
CAASVRRFNQEAAALDNTVVLCISADLPFAHNRFCELEGLTDVIALSVFRSPEFGRDYGVTLTDGPLKGLLSRAVVVVDA
DGRVAYSEQVPEIVQEPDYAAALKALQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 4e-28 45
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-28 45
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 3e-28 45
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-28 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_374648.1 thiol peroxidase VFG0087 Protein 5e-29 45