Gene Information

Name : Plut_0339 (Plut_0339)
Accession : YP_374270.1
Strain : Chlorobium luteolum DSM 273
Genome accession: NC_007512
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 348140 - 348895 bp
Length : 756 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAACGCCGTCATCCTCATTCCCGCCCGCCTCGATTCCAGCCGCCTTCCCCGCAAAATGCTTGCCGACCTTGAGGGTGA
ACCGCTCATCGTGCGTACCTGGCGTCAGGCGCTCCGCTCAAACCTCGCCTCGCGCGTTGTCGTGGCTGCCGACAGCCCTG
AAATCGCCGCCGTGCTCGAACCCCTCGGAGCTGAAGTGGTGCTGACCTCGCCAACGGCCTCCTGCGGCACCGAGCGCATC
GCCGAGGCGGCCCGCAGCATTGAAGCCGATGTCTTCCTGAACCTCCAGGGTGATGAGCCGCTTATCAGTCCCGAGAACAT
CGATCTCGCCCTCCAGCCGTTTTTCGATGCTCCCGCCGGTTCGGCCCTCCCTGACTGCACGACGCTGGTCTTCCCGCTCG
GTCCCGATGACCGGACCCAGATCGATGATCCTCATGTGGTGAAGGTGGTGATGGATGGCGAAGGAAATGCGCTGTACTTC
TCCCGGAGCCCTATCCCTTATGTGCGCAACAGCTCCCCTTCCTTGAGGTTATACCGCCATGTGGGGCTGTATGCCTTCAC
GGCCGAAGTGCTTCAGCGCTTTGCCGCGATGCCGGTGTCGATGCTCGAGGAGGCCGAGTCGCTCGAGCAGCTGCGGCTGC
TTGAAAGCGGGTTCCGCATCCGCTGCGTGAATACAGCCGTCGACAATCCCGGAGTGAATACCCCTGAAGACCTGGAGCTG
GTGAGGAGCCTCCTTCGTCGCGCCTCAAGGGCGTGA

Protein sequence :
MNAVILIPARLDSSRLPRKMLADLEGEPLIVRTWRQALRSNLASRVVVAADSPEIAAVLEPLGAEVVLTSPTASCGTERI
AEAARSIEADVFLNLQGDEPLISPENIDLALQPFFDAPAGSALPDCTTLVFPLGPDDRTQIDDPHVVKVVMDGEGNALYF
SRSPIPYVRNSSPSLRLYRHVGLYAFTAEVLQRFAAMPVSMLEEAESLEQLRLLESGFRIRCVNTAVDNPGVNTPEDLEL
VRSLLRRASRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-36 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-36 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 6e-37 44
unnamed AAK15335.1 unknown Not tested Not named Protein 5e-23 41