Gene Information

Name : guaA (Plut_1946)
Accession : YP_375831.1
Strain : Chlorobium luteolum DSM 273
Genome accession: NC_007512
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2162435 - 2163976 bp
Length : 1542 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAATCTGTCCTGGTACTGGATTTCGGATCACAATACACCCAGCTGATCGCCCGCCGTATCCGCGAACTCGGCATCTA
TTCCGAGATCCTCCCATACAGCACCACGCCTGAGGCCATACGGGAACATGATCCCAAGGCGATCATTCTTTCCGGCGGCC
CTACGAGCGTCTACGGCGAATCGGCCATCCTGCCGCACCCCGGCATTTTCTCGCTCGGCCTCCCCATCCTCGGCATCTGC
TACGGCCTGCAGGCCATTGCCAACCATTTCGGGGGTGCGGTTGAAAGCTCTTCAAAGCAGGAGTTCGGCCGTGCGAAAAT
CCTGGTCGACAGGACGGAAGGCCACGAAAGCATGCTGTTCAAGGACATTCCGGATTCGGACGTATGGATGAGCCACGGCG
ACAAGGTGACCCGCATGCCTGAAGGGTTCCAGATTACCGCCAGCAGCGGCAACTCGGAAATGTGCGCCATCGAGAGCTTC
GGCCCGAAGGCCGCCCTCAAGATCTACGGCCTGCAGTTCCACCCCGAGGTACAGCATACCCTCTACGGCAAACAGCTTCT
TTCGAACTTCCTCATCAACATTGCCGGCATACGGCCCGACTGGTCGTCGAAAAGCTTCATCGAGCACCAGATCGAGGATA
TCCGCCAGCGCGCCGACAAAGGAACGGTCATCTGCGGCATCAGCGGCGGCGTCGACTCCACCGTGGCGGCAGTCCTTGTC
AGCAAAGCCATCGGCAAGCAGCTGCACTGCGTCTTCGTCGACAACGGCCTGCTCCGCAAGAACGAAGCCCGGAAGGTGAT
GGAGTTCCTTAAACCCCTCGGCCTGAACATCACCCTTGCCGACTCCGCGGACCTCTTCCTCGGACGCCTTAAAGGGGTGG
CCTCTCCCGAAAAGAAACGCAAGATCATCGGACGCACCTTCATCCGCGTCTTTGAAGAGCATATCAACGAGGAGAAGTTC
CTCGTCCAAGGGACCCTGTACCCCGACGTCATTGAAAGCCAGAGCGTGAAAGGACCTTCGGAGACGATCAAGTCGCACCA
CAACGTGGGCGGCCTGCCGAAGCGCATGAAACTGAAACTCATCGAACCGCTCCGTGAGCTCTTCAAGGACGAGGTCCGCG
CCGTCGGCCGCGAGCTCGGCATTCCGGAAGACATCCTCATGCGCCACCCCTTCCCGGGCCCGGGCCTCGCCGTCAGGGTG
CTCGGCTCACTCACCAGGGAGCGGCTTGACATACTCCGCGAAGCCGATGAAATCTACATCGACGAGTTGAAGTCCAGCGG
GCTCTACCAGCAGGTATGGCAGGCGTTCTCCGTACTGCTTCCTGTCCAGTCGGTCGGCGTGATGGGTGACAAGCGCACCT
ACGAGAACGTGCTTGCACTGCGTGCCGTGGAGTCCACCGACGGCATGACGGCCGACTGGGCCCACCTCCCGCACGACTTC
CTCGCAAAAGTATCGAACAGGATCATCAACGAGGTCCGCGGCATCAACCGTGTCGCCTACGACATCTCATCGAAACCCCC
GGCCACAATCGAATGGGAATAA

Protein sequence :
MQSVLVLDFGSQYTQLIARRIRELGIYSEILPYSTTPEAIREHDPKAIILSGGPTSVYGESAILPHPGIFSLGLPILGIC
YGLQAIANHFGGAVESSSKQEFGRAKILVDRTEGHESMLFKDIPDSDVWMSHGDKVTRMPEGFQITASSGNSEMCAIESF
GPKAALKIYGLQFHPEVQHTLYGKQLLSNFLINIAGIRPDWSSKSFIEHQIEDIRQRADKGTVICGISGGVDSTVAAVLV
SKAIGKQLHCVFVDNGLLRKNEARKVMEFLKPLGLNITLADSADLFLGRLKGVASPEKKRKIIGRTFIRVFEEHINEEKF
LVQGTLYPDVIESQSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIPEDILMRHPFPGPGLAVRV
LGSLTRERLDILREADEIYIDELKSSGLYQQVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESTDGMTADWAHLPHDF
LAKVSNRIINEVRGINRVAYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-132 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-132 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-132 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-125 50