Gene Information

Name : hemC (Plut_1427)
Accession : YP_375329.1
Strain : Chlorobium luteolum DSM 273
Genome accession: NC_007512
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1610516 - 1611457 bp
Length : 942 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAAAAAACAGCTTATCATCGGCACCAGGTCCAGCCCCCTCGCTCTCTGGCAGGCAGAGTTCACCAAAGCGGAACTCTC
CAGGCACTTTCCTGATCTTGAAATCACACTGAAACTGGTCAAGACCACGGGCGACGTGCTTCTCGACTCTCCCCTGTCAA
AGATCGGCGACATGGGACTGTTCACGAAAGACATCGAAAAGTTCCTGATTGCCAAGGAGATCGACCTTGCCGTCCACAGC
CTCAAGGATGTTCCGACCGCAACCCCTGAAGGGCTGATCATCAGCGCCTTCACCGAACGCGAAGACACCCGCGACGTCAT
CATATCCAAAACGGGCGCCAAACTGCTCGACCTGCCGAAAAACGCCAAGGTAGCGACCAGCAGCCTTCGTCGCATGTCAC
AGCTCAAAAGCCTCCGCCCCGACTTCGAGATCTGCGACATCCGCGGCAACCTCAACACCCGTTTCAAGAAGTTCGACGAA
GGCGAATTCGATGCAATGATGCTTGCCTATGCCGGCGTCTACCGCCTGAACTTCAGCGACCGCATCTCCGAGATCCTGCC
GCATGAAATCATGCTGCCTGCCGTCGGTCAGGGTGCGCTCGGCATAGAGACCCGTGTCGACGACGAACAGACCCGCGAGA
TCGTCAAGGTCATGAACCACAGCACCACCGAGTACTGCTGCAAAGCAGAGCGCGCGCTGCTCCGCCACCTCCAGGGAGGA
TGCCAGATCCCGATCGGCGCCTACGCGTCGTTCAAGAACGGCACCCTGCACCTTCTGGCGTTCGTAGGCTCCACCGACGG
CACCATCGGCATCCGGGACGAAATCACCAAAACAGGACTCACCTCGCCGAGCCAGGCTGAAGAAGCCGGCATTGAACTGG
CCAAGGAGCTCCTGAAGCAGGGCGCCGAAAAGATCCTTTCGGAAATCCGCAAGAGCTGCTGA

Protein sequence :
MKKQLIIGTRSSPLALWQAEFTKAELSRHFPDLEITLKLVKTTGDVLLDSPLSKIGDMGLFTKDIEKFLIAKEIDLAVHS
LKDVPTATPEGLIISAFTEREDTRDVIISKTGAKLLDLPKNAKVATSSLRRMSQLKSLRPDFEICDIRGNLNTRFKKFDE
GEFDAMMLAYAGVYRLNFSDRISEILPHEIMLPAVGQGALGIETRVDDEQTREIVKVMNHSTTEYCCKAERALLRHLQGG
CQIPIGAYASFKNGTLHLLAFVGSTDGTIGIRDEITKTGLTSPSQAEEAGIELAKELLKQGAEKILSEIRKSC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-60 48
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-60 48