Gene Information

Name : lysS (Plut_1357)
Accession : YP_375259.1
Strain : Chlorobium luteolum DSM 273
Genome accession: NC_007512
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1533644 - 1535149 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGCACCAGGACAACGAACAGCTTTCCCTGAATGACCAGATGCAGCGCCGTTTCGACGAGCGGCGCCACCTTCAGGAATC
AGGCATCAACCCCTATCCCTGCAGCTTTGAGGTAACCGGCCATTCCAGGCAGATCATCGAGCACTTCAAGGAAGACGCTG
AGGAAAAAGTATCGGTTGCCGGTCGCATCATGGCCATCCGCAGGATGGGCAAAGCCTCCTTCTTCCATATTCAGGACAGC
GATGGCCGCATGCAGATCTACCTGAAAAAGGACGAAGTCGGAGACGATGCCTACGCCACATTCAAGCTGCTCGACATAGG
TGACATCGTCGGAGTCAACGGCTACACGTTCCGTACCAGAACCGGTGAAATTTCGGTGCATGCCGAGTCCTTCGAACTGC
TCTGCAAATCGCTGCGTCCCATTCCCGTCGCCAAGGAAAAAGAGGTGGAGGGAGAAAAAGTGGTATTCGACGCATTCGCC
GACCGCGAACTGCGCTACCGCCAGCGCTACGTTGACCTCATCGTCAACCCCGAAGTCCGCAGCACCTTCATCAAGAGAAG
CGCCATCGTATCACACATCCGCAGCTTCTTCACGTCCCAAGGGTGGCTCGAGGTTGAAACCCCCATCCTCCAGCCCATTT
ACGGAGGAGCGGCGGCACGCCCGTTCACTACCCACCACAATGCGCTTGACATGCAGCTCTATCTGCGCATTGCCAACGAG
CTCTACCTCAAACGCCTCATTGTCGGCGGCTTCGACGGCGTATTCGAGTTTGCAAAGGACTTCCGCAACGAAGGCATCGA
CCGCTTCCACAACCCGGAATTCACCCAGGTCGAACTCTATGTCGCCTACAAAGATTACGACTGGATGATGCGGCTCGTCG
AGGAACTCTTCCAACAGACCGCCATTGCCGTAAACGGAACGGCAATGACAACGTTCCTCGGCCATGAGATAAGCCTTGAA
GCACCCTTCCGCCGCCTCACCATCGCTGATTCCATTCGGGAGTACACCGGTGCCGAGATTGAAGGTAAAACCGAAACGGA
ACTCCGCAACCTGGCCAAGGACCTCGGACTGGAACTCGATCCGAAAATAGGATCCGGAAAAATCATCGATGAAATCTTCG
GCGAATTCGTAGAGCCGAAGCTCATCCAGCCGACCTTCATTACCGACTACCCGACCGAGATGTCTCCCCTTGCCAAGCCC
CACCGCTCCAAACCGGGACTTGTCGAGCGCTTCGAACTTATCGCCGGCGGCAAGGAGATATGCAACTCCTTCTCGGAACT
CAACGATCCCGTGATCCAGCGCCAGCGGCTTGAAGAGCAGGCGAGCCTCCGCCAGCGCGGTGACGATGAAGCCATGGTGG
TCGACGAAGACTTCCTCCGTGCCCTTGAATACGGCATGCCTCCCACGGCAGGCCTCGGCATCGGCATCGACCGCCTCGTC
ATGCTCATCACCGGAGAGGAATCAATACGCGATGTCATTTTCTTCCCGCACCTTAAGCCGGAATAA

Protein sequence :
MHQDNEQLSLNDQMQRRFDERRHLQESGINPYPCSFEVTGHSRQIIEHFKEDAEEKVSVAGRIMAIRRMGKASFFHIQDS
DGRMQIYLKKDEVGDDAYATFKLLDIGDIVGVNGYTFRTRTGEISVHAESFELLCKSLRPIPVAKEKEVEGEKVVFDAFA
DRELRYRQRYVDLIVNPEVRSTFIKRSAIVSHIRSFFTSQGWLEVETPILQPIYGGAAARPFTTHHNALDMQLYLRIANE
LYLKRLIVGGFDGVFEFAKDFRNEGIDRFHNPEFTQVELYVAYKDYDWMMRLVEELFQQTAIAVNGTAMTTFLGHEISLE
APFRRLTIADSIREYTGAEIEGKTETELRNLAKDLGLELDPKIGSGKIIDEIFGEFVEPKLIQPTFITDYPTEMSPLAKP
HRSKPGLVERFELIAGGKEICNSFSELNDPVIQRQRLEEQASLRQRGDDEAMVVDEDFLRALEYGMPPTAGLGIGIDRLV
MLITGEESIRDVIFFPHLKPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-101 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_375259.1 lysyl-tRNA synthetase VFG1668 Protein 2e-101 47