Gene Information

Name : Bcep18194_B0670 (Bcep18194_B0670)
Accession : YP_371428.1
Strain :
Genome accession: NC_007511
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase/ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 749524 - 751176 bp
Length : 1653 bp
Strand : -
Note : -

DNA sequence : 
ATGCAACCCTCCCTTCCCTCCGTGGCGCCGGCCCTCCCGGCCGATGCGCCCGACTGGCCCGACGACTTCGCGCGCCGCTA
TCGCGACGCCGGCTATTGGCAAGACACGACTTTCTTCGACGCACTCGACGCACAGGCGCAGCGCGATCCCGATGCGCTCG
CCATCGTCGACGGCACCTGCCGGCTCAGCTACCGCGACCTGCTGTCGCGCATCCGCCGGCTTGCGGGCGGCCTCGCCCGT
CTCGGCCTGACGCGCGGCGACGCGGTCGTCGTCCAGCTACCGAACGGCGCGCGCTTCATCGAGACCTGCTTCGCGCTGTT
CCAGCTCGGCGTGCGGCCGGTGCTCGCCCTCCCCGCTCACCGGCACTACGAGGTCGGCGCGTTCTGCCGCTTCGCCGGCG
CGCGTGCGTACCTGGGCGCGGCACAACTCGGCGAGTTCGACTGCCGGCCGCTCGCGGCCGCGTTGCAGGCCGACTGCCCG
ACGCTCGAGCACATCGTGATGGCCGGTGACGACCATGCGTTCACCCCATTCGACGCGCTGTACGACGCGCCGCCGCTGCG
CGAATGCGCGGCACGCGCCGACGACATCGCGTGCTTCCAGCTGTCGGGCGGCACAACCGGCACGCCGAAGCTGATCCCGC
GCCGCCATCGCGAATACCTGTACAACGTGCGCGCGTGCAGCGCCGCGAGCAGCTTCGACGCCGGCACCGTGTATCTCGCC
GCGCTGCCGATGGCGCACAACTTCACGCTGTGCTGCCCCGGCACGATCGGCGCGCTGCTCGCAGGCGGCCGCGTGGTCAC
GACCGGGCGGCCCGAGCCCGAACAGAGCTTCGCGCTGATCGCGCAGGAGCGCGTCACGCATACCGCGCTCGTGCCGCCGC
TCGCGCTGCTGTGGCTCGACGAGCAGCCGCAACGGCAGGCCGACCTGTCGAGCCTGCGCGTGCTGCAGGTCGGCGGCGCG
CGATTGATGGACCACGCGGCCGCGCGCGTCGCGCCCGTGCTCGGTTGCCGGCTTCAGCAGGTGTTCGGCATGGCCGAAGG
GCTCATCTGCTGCACGCGGCTCGACGATTCGCCCGAACGGATCGCGCAGACGCAGGGGCGCCCCGTATCGGACGGCGACG
AAGTGCGCATCGTGGACGATGCCGGCGAACCGGTCGCGCCCGGCGAGATCGGCGAGTTGCAGGTGCGTGGCCCGTACACG
ATCCGCGGCTACTACCGGCTCGCCGAGCACAACGCGACCGCGTTCACCGCCGACGGCTTCTATCGCAGCGGCGACCGCGT
GCGGCGCACCGCGGACGGCGACCTCGTCGTCGAAGGCCGCGACAAGGACCAGATCAATCGCGGCGGCGAGAAGGTCTCCG
CCGAGGAAGTGGAGAACCTGTTGCTCGCGCATCCGCAGGTGCACGACGCGGCGGTCGTCGCGATGCCCGACCCGCTGCTC
GGCGAGCGCACGTGCGCATTCGTCGTCGCCCGCGCGCCCGCACCGTCCAGGCTGGTGCTGAAACGCTACCTGCGCGACTG
CGGGCTCGCGGCGTTCAAGATTCCCGATCGCATCGAGTTCATGCCGCGCTTCCCGGAAACCGGCATCGGCAAGACCAGCA
AGAAATCGCTGCGCGACCTGCTGCGCCGTCAGTTGCAGGCGGCCGCCGCATGA

Protein sequence : 
MQPSLPSVAPALPADAPDWPDDFARRYRDAGYWQDTTFFDALDAQAQRDPDALAIVDGTCRLSYRDLLSRIRRLAGGLAR
LGLTRGDAVVVQLPNGARFIETCFALFQLGVRPVLALPAHRHYEVGAFCRFAGARAYLGAAQLGEFDCRPLAAALQADCP
TLEHIVMAGDDHAFTPFDALYDAPPLRECAARADDIACFQLSGGTTGTPKLIPRRHREYLYNVRACSAASSFDAGTVYLA
ALPMAHNFTLCCPGTIGALLAGGRVVTTGRPEPEQSFALIAQERVTHTALVPPLALLWLDEQPQRQADLSSLRVLQVGGA
RLMDHAAARVAPVLGCRLQQVFGMAEGLICCTRLDDSPERIAQTQGRPVSDGDEVRIVDDAGEPVAPGEIGELQVRGPYT
IRGYYRLAEHNATAFTADGFYRSGDRVRRTADGDLVVEGRDKDQINRGGEKVSAEEVENLLLAHPQVHDAAVVAMPDPLL
GERTCAFVVARAPAPSRLVLKRYLRDCGLAAFKIPDRIEFMPRFPETGIGKTSKKSLRDLLRRQLQAAAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 9e-99 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-97 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-98 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-98 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-98 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-98 50
ybtE CAA21394.1 - Virulence HPI Protein 1e-98 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 8e-98 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-98 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcep18194_B0670 YP_371428.1 AMP-dependent synthetase/ligase VFG0168 Protein 2e-169 69
Bcep18194_B0670 YP_371428.1 AMP-dependent synthetase/ligase VFG0932 Protein 3e-101 46
Bcep18194_B0670 YP_371428.1 AMP-dependent synthetase/ligase VFG1817 Protein 1e-89 46