Gene Information

Name : murD (Bcep18194_A3643)
Accession : YP_367888.1
Strain :
Genome accession: NC_007510
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 527338 - 528849 bp
Length : 1512 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGTTTGGAGATCGGCAACGGCCGATGGTGCTCGTACTGGGGCTCGGGGAATCGGGTCTCGCGATCGCGCGATGGTGCGC
GAGGCACGGGTGCCGGCTGCGTATTGCCGATACCCGCGAGGCGCCGCCGAACCTTGCCGCGCTGCAGGCCGAAGGCATCG
ATGCGGAATTCGTCGGCGGGGCGTTCACGCCTGCGCTGCTCGACGGCGGTATCGAGCTCGTCGGGCTGAGCCCCGGGCTG
TCGCCGCTCGAACCGGCACTCGCAGCGCTGGTCGCAGCTGCGAACGAGCAGGGCGTCGCGGTGTGGGGCGAGCTGGAATT
CTTCGCGCAGGCGCTGCGTGCACTCGGCACGAGCGGCTACCAGCCGAAGGTGCTCGCGATCACGGGCACCAACGGCAAGA
CTACGACGACGAGCCTCACGGGCCTGCTGTGCCAGCGCTCGGGCAAGAAGGTCGCCGTCGCGGGCAACATCAGCCCCGCG
ATGCTCGACCGGCTCGCCGCCGCGATCGACGAAACCGCGCTGCCCGACGTGTGGGTGCTCGAACTGTCGAGCTTCCAGCT
CGAGACCGCGCGCACGTTCGCGCCCGATGCGGCCGCGATCCTCAACATCACGCAGGACCACCTCGACTGGCACGGCAGCT
TCGACGCGTACGCGCAGGCAAAGGGCCGGATCTTCGGCGCAACGACCACGCGCGTGCTGAACCGCGACGATGCGGCCGTA
ATGAAGTTCGCGCCGGCAGCCGGCGCGGCCGATGCGCCGCGCACGGTCACGTTCGGCCTGAACGAACCGGTGCAGGACGG
CGACTACGGGCTGTCGCGCGACAACGGCATCGCGTGGCTGGTGGAAGCCGTCGATCGCGACGCCCCGGATGAAGCTGCGA
CGACGACCCGTCGGCGCAAGCGCGACGCCCATACGCCCGACATCGCGCAGAAGCGCCTGATGCCGGCCGACGCCCTGCGC
ATCCGCGGGCTGCACAACGCGGCGAACGCGCTGGCCGCATTCGCGCTCGCACGCGCGATCGACCTGCCGGCCGCGCCGCT
GCTGCACGCGCTGCGCGAATACCGCGGCGAGGCGCATCGCGTCGAAGTGATCGCGACGATCGACGACGTGGACTACGTCG
ACGACAGCAAGGGTACGAACGTCGGCGCGACGGTTGCCGCGCTCGACGGGCTGGCACAGAAGATCGTGCTGATCGCGGGC
GGCGACGGCAAGGGGCAGGATTTCGCACCGCTGGTTGCGCCGGTCGCGCGCTGGTGCCGCGCGGTGATGCTGATCGGCCG
TGATGCGCCGGCGATCCGCGACACGCTCGCCGAAACGGGTGTGCCGCTCGCCGACCACGTGACGCTCGAAGGGGCGGTGC
ACGCGGCAGCCGACCTCGCCGAACCGGGCGATGCAGTGCTGCTGTCGCCTGCATGCGCGAGCCTCGACATGTTCAGGAAC
TACGCCCATCGCGCGGATGTGTTCCGCGCGGCGGTCGACGAAATCGCCATCGACAAAGGAGCGACGCCATGA

Protein sequence :
MFGDRQRPMVLVLGLGESGLAIARWCARHGCRLRIADTREAPPNLAALQAEGIDAEFVGGAFTPALLDGGIELVGLSPGL
SPLEPALAALVAAANEQGVAVWGELEFFAQALRALGTSGYQPKVLAITGTNGKTTTTSLTGLLCQRSGKKVAVAGNISPA
MLDRLAAAIDETALPDVWVLELSSFQLETARTFAPDAAAILNITQDHLDWHGSFDAYAQAKGRIFGATTTRVLNRDDAAV
MKFAPAAGAADAPRTVTFGLNEPVQDGDYGLSRDNGIAWLVEAVDRDAPDEAATTTRRRKRDAHTPDIAQKRLMPADALR
IRGLHNAANALAAFALARAIDLPAAPLLHALREYRGEAHRVEVIATIDDVDYVDDSKGTNVGATVAALDGLAQKIVLIAG
GDGKGQDFAPLVAPVARWCRAVMLIGRDAPAIRDTLAETGVPLADHVTLEGAVHAAADLAEPGDAVLLSPACASLDMFRN
YAHRADVFRAAVDEIAIDKGATP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 6e-42 41
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 6e-42 41