Gene Information

Name : guaA (XCV2485)
Accession : YP_364216.1
Strain : Xanthomonas campestris 85-10
Genome accession: NC_007508
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2803985 - 2805550 bp
Length : 1566 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCAACATCCATACCGACAAGATCCTCATCCTCGACTTCGGTGCGCAGTACACCCAGCTGATTGCGCGGCGTATTCG
CGAGATCGGGGTCTACTGCGAGATTTGGGCGTGGGATCACGATCCGTCGGAGATTGCCGGTTTCGGTGCCAAGGGCATCA
TCCTGTCCGGCGGCCCGGAGTCGACCACGTCGCCGGGCGCACCGGTGGCGCCGCAGGAAGTGTTCGATAGCGGCCTGCCG
GTGTTCGGTATCTGCTACGGCATGCAGACCCTCGCCGCGCAATTGGGTGGTGCGACCGAGGCAGCGGATCAACGCGAATT
CGGCCATGCCGAAGTGGACGTGGTGGCGGCAGATGCCTTGTTCTCCGGCCTCACCGACCACGCCGGCGCCTCGCGCCTGA
ATGTATGGATGAGCCACGGCGACCACGTGTCGCAGGTGCCACCGGGCTTCACCATTACCGCCACGACCGACCGCATCCCG
GTGGCGGCCATGTCCAACGAAGCCAAGCGTTGGTACGGCGTGCAGTTCCATCCTGAGGTGACGCATACCTTGCAGGGCCA
GACCTTGCTGCGTCGCTTCGTGGTGGATGTCTGCGGCTGCCAGACGCTGTGGACCGCGGCCAACATCATCGAGGACCAGA
TCGCGCGCGTGCGCGAACAGGTGGGCGACGATGAAGTGATTCTTGGGTTGTCCGGCGGCGTCGATTCGTCGGTGGTGGCC
GCGCTGCTGCACAAGGCGATCGGCGACAAGCTGACCTGCGTGTTCGTCGATACCGGCTTGCTGCGTTGGCAGGAAGGCGA
CCAGGTGATGGCGATGTTCGCCGAGCACATGGGCGTCAAGGTGATTCGCGTCAACGCCGCCGACCGTTATTTCGCCAAGC
TTGAAGGCGTCAGCGACCCGGAAGCCAAGCGCAAGATCATCGGCAACCTGTTCGTGGAGATCTTCGACGAAGAATCCAAC
AAGCTGGCCAATGCCAAGTGGCTGGCGCAGGGTACGATCTATCCGGACGTGATCGAGTCGGCGGGCAGCAAGACCGGCAA
GGCGCACGTGATCAAGAGCCACCATAACGTCGGTGGCTTGCCCGAGCACATGAAGCTGGGCCTGGTCGAGCCGCTGCGCG
AATTGTTCAAGGACGAGGTGCGTCGCCTTGGCGTGGAACTCGGCCTGCCGCGCACCATGGTGTATCGCCACCCGTTCCCG
GGCCCCGGCCTGGGCGTACGCATCCTGGGCGAAGTGAAGCGCGAGTACGCCGAGTTGCTGGCCAAGGCCGACGCGATCTT
CATCGACGAACTGCGCAAGGCCGACCTGTACGACAAGACCAGCCAGGCCTTCGCCGTGTTCCTGCCGGTGAAGTCGGTCG
GCGTGGTCGGCGACGCCCGCGCCTACGAATGGGTGATCGCGCTGCGCGCGGTGGAGACCATCGACTTCATGACCGCGCAT
TGGGCGCACCTGCCGTACGACTTCCTCGGCACCGTGAGCAACCGCATCATCAACGAGCTGCGTGGTGTGTCGCGCGTGGT
CTACGACATCTCCGGCAAGCCGCCGGCGACGATCGAGTGGGAGTGA

Protein sequence :
MTNIHTDKILILDFGAQYTQLIARRIREIGVYCEIWAWDHDPSEIAGFGAKGIILSGGPESTTSPGAPVAPQEVFDSGLP
VFGICYGMQTLAAQLGGATEAADQREFGHAEVDVVAADALFSGLTDHAGASRLNVWMSHGDHVSQVPPGFTITATTDRIP
VAAMSNEAKRWYGVQFHPEVTHTLQGQTLLRRFVVDVCGCQTLWTAANIIEDQIARVREQVGDDEVILGLSGGVDSSVVA
ALLHKAIGDKLTCVFVDTGLLRWQEGDQVMAMFAEHMGVKVIRVNAADRYFAKLEGVSDPEAKRKIIGNLFVEIFDEESN
KLANAKWLAQGTIYPDVIESAGSKTGKAHVIKSHHNVGGLPEHMKLGLVEPLRELFKDEVRRLGVELGLPRTMVYRHPFP
GPGLGVRILGEVKREYAELLAKADAIFIDELRKADLYDKTSQAFAVFLPVKSVGVVGDARAYEWVIALRAVETIDFMTAH
WAHLPYDFLGTVSNRIINELRGVSRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-126 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-126 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-126 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-113 49