Gene Information

Name : leuS (CHY_0393)
Accession : YP_359254.1
Strain : Carboxydothermus hydrogenoformans Z-2901
Genome accession: NC_007503
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 336058 - 338523 bp
Length : 2466 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAAAGGTATGATTTTAAAGCTATTGAAGCTAAGTGGCAGAAAAAATGGGAGGAATTAAAACTTTACGAAGTGGA
CGATTTTTCGGAAAAACCGAAATATTACTGTTTGGAAATGTTTCCTTATCCTTCGGGGAAACTTCATATGGGGCACGTCC
GCAATTACTCCATTGGGGATGTGGTAGCCCGGTACAAGCGGATGCGGGGCTATGCTGTGTTACACCCTATGGGCTGGGAT
GCTTTTGGGCTTCCGGCGGAAAATGCGGCGATTAAACACGGTAATGTTCATCCGGCGGATTGGACCTGGGATAATATTGC
CAATATGAGACGGCAGTTAAAGGAGTTAGGTATTTCTTACGACTGGCGGCGGGAGATAGCTACCTGTCATCCGGAATACT
ACCGGTGGACCCAGTGGCTCTTTTTACAGTTTTATAAAAAGGGGCTTGCCTACAAGAAAAAAGCTCCGGTAAACTGGTGC
CCCGGCTGTCAGACGGTTCTGGCTAACGAACAGGTGATAGACGGGGAGTGCGAACGCTGCCATTCCCGGGTGGAGAAAAA
GGAGTTAGAACAGTGGTTCTTTAAAATTACCGCTTATGCCGAAAGACTTCTGCAGGATATTAAAAAGCTTACCGGCTGGC
CGGAAAAGGTAAAAATCATGCAGGAAAACTGGATCGGAAGATCCGAAGGGGCGGAAATTACTTTTAAAATAAAGGGGCAT
GAGGAAACAATATCGGTGTTTACCACCCGGCCCGACACTATTTTCGGAGTAACCTATATGGTTTTGGCGCCGGAACATCC
TCTGGTTGAAAAAATTTCCCGGGGGACTCAGTACGAAAAGGATGTTTTGGAATTTAAACGGAAAATGATGTACTTGTCCG
AAATTGAAAGAACCGCCGAGACCGCAGAAAAAGAAGGGGTTTTTACGGGAGCTTATGCTATAAATCCCTTTACCGGGGAA
GAGATTCCCATACTTTTAGCCAACTATGTTTTAGTGGAGTACGGTACCGGTGCGGTTATGGGGGTGCCGGCCCACGACCA
GCGGGACTTCTTATTTGCCAAAAAATACAATTTGCCCATAAAAGTGGTAATAACCCCTCCGGGGCAAGAATTGAAAGCCG
AGGAGTTAACGGAAGCCTATACCGGAGAAGGAATTCTGGTCAATTCCGGCGAGTTTACCGGGTTAGCCAACAAAGAGGCA
ATCAGGATAATTACCCAAGAAGCGGAAAAGCGGGGATTTGGTAAATATCGAGTAAATTACAGGCTTCGGGACTGGCTTAT
TTCCCGGCAAAGGTACTGGGGTGCTCCCATTCCGGTGCTGTACTGTGAAAAGTGCGGAATTGTTCCCGTACCCGAGGACC
AGCTGCCGGTAGTTTTACCGTATAATGTAGAATTTCGTCCTACCGGGGAAAGTCCCTTAAAGTACGTTCCCGAGTTTTTA
AATGCCACCTGTCCCGAGTGCGGTGGACCTGCAACCCGGGAAACGGACACGATGGATACGTTTATTTGTTCGTCCTGGTA
TTACTATCGTTATACTTCGCCCCGGGATAAACAACAGCCCTGGAGCAAAGAAAAGGTGGAAAGATGGTTGCCGGTGGACC
AGTATATCGGCGGGGTAGAACATGCTATTTTGCACCTTTTATATTCCCGGTTTTTCACCAAAGTCCTCTATGACCTGGGA
TTGGTTCATGTGGACGAACCCTTTACCAATCTTTTGACCCAGGGCATGGTATTAAAAGATGGGGCCAAGATGAGTAAATC
CAAAGGAAATGTGGTAAGTCCCGAAGAAATCGTGGAAAAATACGGGGCCGATACCGCCCGGTTGTTTATTCTTTTTGCGG
CGCCCCCGGAACGGGATTTAGAGTGGAGCGACCAGGGGGTAGAGGGAAGCTTTCGCTTTTTAAACCGGGTGTGGCGGCTA
ATTTACCAGACCAAGGACCGGATATCCGATGAACTTCGGGAATTTTCGGCAAAAGATAAAGAATTAAATCGCCTGTTACA
CGCCACCATTAAAAAGGTAACCGAGGATATTGAAGAAAGGTTTAACTTTAATACGGCAATTTCGGCAATTATGGAGTTAG
TGAACGGTCTTTACCAGTACAAAGAAGGGGAAATTAATCCCGGCCTTTTAAAAGAAGCGTTAAACAAACTGGTGATACTT
CTGGCACCTTTTGCGCCTCATATTGCCGAGGAATTATGGGAGGCATTGGGCAATAAACAAAGTGTTCACTTAGAAAAATG
GCCAGAGTATGATGAAGAAGCTCTAATTACCGAGGAAGTGGAAATAGTTATTCAGGTTAACGGTAAAGTCAAGGACCGGG
TAATGGTTCCGAGAAATGCGGCGGAAGATGAGTTAAAGGAAATTGCCTTAAATACGCCGAAAATAAAAGAATTGACCGCC
GATAAAAAAATTATTAAAGTTATTATAGTACCGGAAAAATTAATTAATATTGTGGTAGCGGGGTAA

Protein sequence :
MQERYDFKAIEAKWQKKWEELKLYEVDDFSEKPKYYCLEMFPYPSGKLHMGHVRNYSIGDVVARYKRMRGYAVLHPMGWD
AFGLPAENAAIKHGNVHPADWTWDNIANMRRQLKELGISYDWRREIATCHPEYYRWTQWLFLQFYKKGLAYKKKAPVNWC
PGCQTVLANEQVIDGECERCHSRVEKKELEQWFFKITAYAERLLQDIKKLTGWPEKVKIMQENWIGRSEGAEITFKIKGH
EETISVFTTRPDTIFGVTYMVLAPEHPLVEKISRGTQYEKDVLEFKRKMMYLSEIERTAETAEKEGVFTGAYAINPFTGE
EIPILLANYVLVEYGTGAVMGVPAHDQRDFLFAKKYNLPIKVVITPPGQELKAEELTEAYTGEGILVNSGEFTGLANKEA
IRIITQEAEKRGFGKYRVNYRLRDWLISRQRYWGAPIPVLYCEKCGIVPVPEDQLPVVLPYNVEFRPTGESPLKYVPEFL
NATCPECGGPATRETDTMDTFICSSWYYYRYTSPRDKQQPWSKEKVERWLPVDQYIGGVEHAILHLLYSRFFTKVLYDLG
LVHVDEPFTNLLTQGMVLKDGAKMSKSKGNVVSPEEIVEKYGADTARLFILFAAPPERDLEWSDQGVEGSFRFLNRVWRL
IYQTKDRISDELREFSAKDKELNRLLHATIKKVTEDIEERFNFNTAISAIMELVNGLYQYKEGEINPGLLKEALNKLVIL
LAPFAPHIAEELWEALGNKQSVHLEKWPEYDEEALITEEVEIVIQVNGKVKDRVMVPRNAAEDELKEIALNTPKIKELTA
DKKIIKVIIVPEKLINIVVAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-175 47