Gene Information

Name : serS (CHY_2697)
Accession : YP_361479.1
Strain : Carboxydothermus hydrogenoformans Z-2901
Genome accession: NC_007503
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2386430 - 2387704 bp
Length : 1275 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATATTAAAAAAGTACGGCAAAACCCGGAAATAGTGGTGGAAGCATTAAAAAAGCGGGGGGCAAACTTAAACCT
CGATGAGTTTTTGCGCTTGGATGAAGAGCGAAGAAAGCTTTTGGTGGATGTTGAGCAAAAAAAATATAAGAGAAACACCG
TTTCCGAAGAAATTGGCAGGCTTAAAAAACAGGGGCTCCCGGCGGATGATTTAATCTTAGAAATGCGGGCGTTATCCGAT
GAAATTAAGAAACTTGATGATGAAGTGGCCCAAATTGAAGAAAAGTTACATGCCATCCTTCTTACTATTCCCAATATCCC
CCACGAGTCGGTGCCGGTTGGTAAAGACAGCAGCGAAAATGTAGAAGTGCGGCGGTGGGGTGAACCGCGAAAGTTTACCT
TTACCCCAAAGGCCCACTGGGAAATAGGGGAAGAGTTAGATATCCTGGATTTTGCCCGGGGGAGTAAGGTAACCGGGGCC
CGCTTTACTTTCTACAAAGGTTTAGGGGCGATGTTGGAGCGGGCGGTTATTAACTTTATGCTTGACCTCCACACCCGGGA
ACACGGCTACGTCGAGGTATTTCCACCGTTTATCGTCAATGCCGATTCGATGATGGGTACCGGGCAGCTGCCAAAGTTTG
CTGAAGATATGTTTAAACTTGAAGGGTTAAATTATTACCTTATTCCCACGGCGGAAGTACCGGTAACTAACCTTTACCGG
GAAGAAATTTTAGACGGGGATAAGCTTCCCATATACCACTGTGCTTACAGCGCATGCTTTAGAGCGGAAGCGGGAGCGGC
CGGACGGGATACCCGGGGCTTAATCCGCCAGCACCAGTTTAATAAAGTAGAGTTAGTTAAGTTTGTCAAACCGGAAAACT
CGTATGAGGAGCTGGAAAAACTCACCCGGGATGCGGAAAGGGTCCTGCAACTTTTGGGACTACCTTACCGGGTGGTGGTG
CTTTGCACCGGGGACCTGGGCTTTAGTGCTGCCAAAACTTACGACATAGAAGTATGGCTTCCCAGTTACAATGATTATAA
AGAAATATCTTCCTGCAGTAATTTTGAAGATTTCCAGGCCCGGCGGGCTAAGATCCGCTACAAAGAGCATCCCAAGGCCA
AGCCGGAGTTTGTCCACACCTTAAACGGCTCGGGCCTGGCGGTGGGCCGGACGGTGGCGGCTATTTTAGAAAATTATCAG
AATGAAGATGGTTCGGTTACGGTACCGGAAGTTTTACGGCCTTATATGGGAGTGGACCGGATTTATAAAAAATAA

Protein sequence :
MLDIKKVRQNPEIVVEALKKRGANLNLDEFLRLDEERRKLLVDVEQKKYKRNTVSEEIGRLKKQGLPADDLILEMRALSD
EIKKLDDEVAQIEEKLHAILLTIPNIPHESVPVGKDSSENVEVRRWGEPRKFTFTPKAHWEIGEELDILDFARGSKVTGA
RFTFYKGLGAMLERAVINFMLDLHTREHGYVEVFPPFIVNADSMMGTGQLPKFAEDMFKLEGLNYYLIPTAEVPVTNLYR
EEILDGDKLPIYHCAYSACFRAEAGAAGRDTRGLIRQHQFNKVELVKFVKPENSYEELEKLTRDAERVLQLLGLPYRVVV
LCTGDLGFSAAKTYDIEVWLPSYNDYKEISSCSNFEDFQARRAKIRYKEHPKAKPEFVHTLNGSGLAVGRTVAAILENYQ
NEDGSVTVPEVLRPYMGVDRIYKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-129 65