Gene Information

Name : CHY_2348 (CHY_2348)
Accession : YP_361153.1
Strain : Carboxydothermus hydrogenoformans Z-2901
Genome accession: NC_007503
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2103669 - 2106104 bp
Length : 2436 bp
Strand : -
Note : identified by similarity to SP:P37571; match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGTTTGACAAGTTTACCCAAAGAGCCCAAAAAGTTATTAGAATGGCTCAGGAAGAAGCAAGAAAAATGAATTATCCTTA
TGTAGCTACGGAACATCTGCTTTTGGGAATTATAAATGAAGGAGAAAGTGTTGCGGCAAAAGTTTTAGAAAACCTTGGTA
TTGATGGCCAGAAAGTTCGGGAAAAAATTTTAGAACTGGTTGGCCCCGGGGAAGGGCCGATGCCGGCGGAGATTGCTTTT
ACCCCAAGGGCAAAAAGAGTTTTGGAACTATCGGTAGATGAGGCGGCCCGGTTTGGCCATAACTATGTTGGTACTGAACA
TTTGCTTTTGGGTTTAATCCGGGAAGGAGAAGGGGTGGCCGCCAGAGTTTTGGTAAGCCTCGGTGCTGATTTGGAAAGGG
TACGGGCTGAAATTACCCAGGTGCTAAGTGGTGGCCCAATTCCCGGAACCTCCGGCCAGGCCGGTGGACAAGCAAAGAAG
AAAGCTGTTAGAACTCCCACCCTTGATGAGCATGGCCGGGATTTAACGGCTTTAGCCCGGGAAAATAAATTAGACCCGGT
GGTAGGCCGGGAGAAGGAAATTGAAAGGGTAATTCAAGTTTTATCCCGCAGAACCAAAAACAATCCGGTTTTAATTGGGG
AGCCGGGAGTAGGTAAGACGGCAATTGTGGAGGGGCTTGCCCAGAGAATTGTGCAAAAGAAAGTTCCCGAGATTTTAATT
GATAAACGGGTTGTGACCCTCGATTTAGCATCAATGGTTGCCGGAACTAAATATCGGGGAGAATTTGAGGAAAGGCTTAA
AAAGGTCTTAGAAGAAATTAAAAATGCTGGAAACGTTATCGTATTTATTGATGAAATCCATACCTTAATTGGGGCAGGGG
CTGCCGAAGGGGCGATTGATGCTGCCAATATCTTAAAACCGAGCCTTGCCCGGGGTGAAATTCAGTGTGTAGGTGCGACC
ACTTTAGATGAATATCGGAAATATATAGAAAAGGACCCGGCTTTAGAACGGCGGTTCCAGCCAATAATGGTAGATGAACC
AACGGTTGAAGAAACAGTTGAAATCTTAAAAGGCTTAAGGGACCGGTACGAAGCTCACCACCGGGTAAAAATTACCGATG
AAGCCATTATTGCCGCTGCAAAGCTTTCGGATCGGTATATTACCGATCGCTTCCTACCGGATAAGGCTATTGACTTGATT
GATGAAGCGGCATCAAGAGTTCGTTTAAATGCCTTTACTGCACCGCCCAATTTAAAAGAGTTAGAAGAAAAAATTAACGA
AATCCGCAAGGAAAAGGAAGCGGCGGTAGCTGCTCAGGAGTTTGAAAAAGCAGCCAAATTAAGAGACCAGGAGCAAAAGC
TTAAAGCAGAGCTTGAGGAAAAGAAGAAAGAGTGGGAAAAAGAGCAAAGCGACCATTTATTATCGGTTACCGAAGACGAT
ATTGCCCAGATTGTTTCGCAGTGGACCGGTATTCCGGTCAAAAAACTTGCCGAAGAAGAATCGGAACGATTACTTAAGCT
TGAGGAAATTTTGCACCAGCGGGTAATAGGCCAGGATGAAGCAGTAAAAGCTGTAGCCCGGGCAGTGAGAAGAGCACGGG
CGGGTCTTAAAGATCCCAAGCGACCCATCGGATCGTTTATTTTCTTAGGTCCGACGGGTGTTGGGAAAACTGAGCTGGCA
CGGGCATTAGCCGAAGCTTTATTTGGAGATGAAGATGCGTTAATTCGGATAGATATGTCAGAGTATATGGAAAAACACAC
GGTAGCTCGCCTAATCGGTGCACCGCCGGGCTATGTTGGTTATGAAGAAGGAGGGCAGCTCACCGAAGCGGTAAGGCGGA
AGCCTTATTCGGTGATCTTACTTGACGAAATTGAGAAAGCTCACCCCGAGGTCTTTAACATCTTGTTGCAGGTATTAGAA
GATGGGCGACTTACCGACTCTAAAGGGCGTACGGTAGACTTTAAAAATACCGTAATAATCATGACCTCCAACATCGGAGC
ACATCTAATAAAGAAAGAAGCCCGTTTAGGCTTTAAAAATGTAGCCGACGAGAAAAAAGAAGAGGATATCAAGGAGAAGT
TAATGGCGGAACTCAAGCGTACTTTCCGGCCGGAATTTTTAAACCGGATTGATGAGATTATTGTCTTCCATTCGTTAACA
GAAGAACACTTAAAGCAAATAGTCCGGTTGATGCTAAAAGAAGTAGGCAAACGTTTGGAAGAACAGGAGATGAAGGTAGA
ATTTGACGACTCCTTAATTGAAGTAATACTTAAAGAAGGTTATGATGAAGCTTTTGGTGCTCGACCGCTGCGGCGGGCTA
TTCAAAAGATAGTAGAAGATAAGTTGTCGGAAGAGCTTCTTTTGGGAAACATCAAAAAAGGAGATACGGTAAAACTGTAT
GCGGAAGATGGGCAAATCAAGGTAGCAAAAATTTAA

Protein sequence :
MFDKFTQRAQKVIRMAQEEARKMNYPYVATEHLLLGIINEGESVAAKVLENLGIDGQKVREKILELVGPGEGPMPAEIAF
TPRAKRVLELSVDEAARFGHNYVGTEHLLLGLIREGEGVAARVLVSLGADLERVRAEITQVLSGGPIPGTSGQAGGQAKK
KAVRTPTLDEHGRDLTALARENKLDPVVGREKEIERVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVQKKVPEILI
DKRVVTLDLASMVAGTKYRGEFEERLKKVLEEIKNAGNVIVFIDEIHTLIGAGAAEGAIDAANILKPSLARGEIQCVGAT
TLDEYRKYIEKDPALERRFQPIMVDEPTVEETVEILKGLRDRYEAHHRVKITDEAIIAAAKLSDRYITDRFLPDKAIDLI
DEAASRVRLNAFTAPPNLKELEEKINEIRKEKEAAVAAQEFEKAAKLRDQEQKLKAELEEKKKEWEKEQSDHLLSVTEDD
IAQIVSQWTGIPVKKLAEEESERLLKLEEILHQRVIGQDEAVKAVARAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELA
RALAEALFGDEDALIRIDMSEYMEKHTVARLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQVLE
DGRLTDSKGRTVDFKNTVIIMTSNIGAHLIKKEARLGFKNVADEKKEEDIKEKLMAELKRTFRPEFLNRIDEIIVFHSLT
EEHLKQIVRLMLKEVGKRLEEQEMKVEFDDSLIEVILKEGYDEAFGARPLRRAIQKIVEDKLSEELLLGNIKKGDTVKLY
AEDGQIKVAKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CHY_2348 YP_361153.1 negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 67