Gene Information

Name : hemC (CHY_1208)
Accession : YP_360051.1
Strain : Carboxydothermus hydrogenoformans Z-2901
Genome accession: NC_007503
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1074465 - 1075400 bp
Length : 936 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAAAAAGAAGTTATTGTGGGGAGTCGAGATAGTGCTTTAGCTTTGTGGCAAACAAATTGGGTGGTGGAAAGACTAAG
CAAAATTCACCCAGAAATAAATTTTAAAATTGTGACCATGAAAACAAAAGGGGATAAAATCCTGGACGTAGCTCTGGCCA
AAATTGGGGACAAAGGGCTTTTCACTAAAGAATTAGAACATGCCTTGTTAAATAAAACCATAGATATGGCTGTCCATAGC
ATGAAAGACTTACCAACAGTTTTGCCCGAAGGCTTGAAAATTGGTGCGTTTTGTGAAAGGGAGTACCCGGGAGATGTTTT
TATTTCCCCCAAGGGTTTTAAGTTTTTGGAACTACCTCAGGGGGCGAGAATTGGTACCAGCAGTTTGCGGCGGATAGCCC
AAATTTTAGCCGTAAGGCCGGATTTACAAGCCATACCGCTGCGCGGAAACCTACCTACACGTTTTCGTAAAATGGAGGAA
ATGGACTTAGATGGCATTATCTTGGCTTATGCCGGTGTGAAAAGATTGGGTTATGAGGATAAAATTACCGAGATGTTAAG
TTTTGACCTCTGTTTACCGGCGGTTGGTCAAGGTTCGATAGGTGTGGAAATCCGTGCCGATGATACTTTTATCGAAGAGC
TTTTAAAACCAATCGATCATTTTGCAACAAACCGAGCTATTAGAGCAGAAAGGGCCTTCTTAAAGCGCTTGGAAGGAGGA
TGTCAAATCCCCATTGGCGCCTATTCTGAAGTTAAAGAAAACCGACTTCATTTGAAAGGCGTTGTTGCCAGTTTAGATGG
GAAGTTAGTTATTAAAGGTGAAAAAGAGGGAAGTATTGAGGAACCGGAGAAAGTGGGGATTAGTTTAGCGGAGGAACTTT
TAACGAAAGGCGCCCAAAAAATCTTAGAGGAAATCAGGCGGGATGCCAATGAGTAA

Protein sequence :
MKKEVIVGSRDSALALWQTNWVVERLSKIHPEINFKIVTMKTKGDKILDVALAKIGDKGLFTKELEHALLNKTIDMAVHS
MKDLPTVLPEGLKIGAFCEREYPGDVFISPKGFKFLELPQGARIGTSSLRRIAQILAVRPDLQAIPLRGNLPTRFRKMEE
MDLDGIILAYAGVKRLGYEDKITEMLSFDLCLPAVGQGSIGVEIRADDTFIEELLKPIDHFATNRAIRAERAFLKRLEGG
CQIPIGAYSEVKENRLHLKGVVASLDGKLVIKGEKEGSIEEPEKVGISLAEELLTKGAQKILEEIRRDANE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-67 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-67 49