Gene Information

Name : pyk (CHY_1144)
Accession : YP_359989.1
Strain : Carboxydothermus hydrogenoformans Z-2901
Genome accession: NC_007503
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1018022 - 1019773 bp
Length : 1752 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGAAACGCACCAAGATTGTTTGTACAATTGGGCCGGCTTCAAACGACGTAGGTATCTTAAAAGAAATGATTATATCCGG
AATGAATGTGGCCAGAATTAATTTTGCTCATGGCAGTCACGAGGAGCACCGGGAGAGAATTGAAAAGGTTAGACGGGCGT
CTTTAGAAGTAGGAATCCCGGTGGCAATTTTAATTGATACAAAAGGTCCGGAAATTCGCATTGGTAAAGTTGAAAACGGA
AAAATTGTCTTAAAAGAAGGGGACTTAGTGGTATTTGATCCGGATATAGCAGAGGGTCAAGGTTTGAGAGTTCCAGTAAA
TTATCCGGGATTAGCCCGGGATGTTAATGTCGGAGGAACTATTCTTTTAGATGATGGGTTAATAGAATTGAAAATCGAAG
ATATTCAGGGTAATAAAGTTATTGCCCGGGTTATAACCGGTGGTGAGTTATCCAATAACAAAGGAGTAAATTTACCGGGA
GTTAAAGTTAATCTTCCGGCGTTAACCGAAAAGGACCGGAAGGATATTGATTTTGGTATTGAAATTGGAGCGGACTTTAT
TGCCCACTCTTTTGTCCGAAAAGCAGCGGATGTGTTAGCTTTACGGCGTTACCTGGAAGAAAAAGGGGCGGATATGGAAA
TAATTGCTAAAATCGAAAACCAAGAAGGGGTCGAAAACATCGATGAAATCATCAAAGTTGCGGATGGGATAATGGTTGCC
CGGGGGGATCTGGGAGTAGAAATTCCAACGGAAGATGTGCCTTTGGTGCAAAAGGAAATAATTGAAAAGTGTAATAAAAA
TGGTAAACCGGTAATCACCGCCACCCAGATGTTAGATTCAATGATTAGAAATAAACGTCCGACCCGGGCCGAAGCTACCG
ATGTGGCTAATGCTATTTTTGACGGCACCGATGCGGTAATGCTGTCGGGAGAAACGGCTGCCGGGAAATATCCGGTAGAA
GCGGTTAAAACAATGGCCCGGATTGCGGAAAAAGCGGAAGAAAAATTACTCACGTTACGAAAACTAAATAAACCCACCAC
AAAATCTTTTAAAACTGTAACCGATGCCATAAGCCACGCCAGTGTTACCACCGCTGAAGAATTGGATGCGGGGGCAATTA
TCACGCCTACTTCTTCGGGCTATACGGCGCGAATGGTTTCCCGGTACCGCCCGGCGGTTCCTATTATTGCTGCCACACCG
GATATGAAGGTACTTAGAAAGTTGACGCTGGTTTGGGGGGTATTTCCCCTTTTGGTTAAAACCTCCGATTCTACCGATGA
AATGTTAAGTAAAGCAATAGAAGCCTCTTTAGAAAGTGGGCTTTTAAAACCTGGCGATTTGGTGGTGCTTACCGCCGGAG
TTCCGGTGGGCGTAAAAGGGACAACCAACCTTTTAAAAGTCCATGTAGCGGGAAATGTTTTGGCCAAAGGTGTGGGCATT
GGAACAAGGCCTATAACCGGAACGGCTCGGGTCTGTCGAACCGCCAGGGAAGCAATCGAGCGGATTCAGCCGGGAGATAT
TTTGGTAACCGAAGCAACCGACAGAGATTTTGTTTCGGCTATTGAAAAGGCCGCGGGACTGGTAGTTGAAGCGGGAGGAC
TTACGTCGCATGCGGCTATTGCGGGGTTAGAGTTTGGGATACCTGTAATAGTTGGGGTCGATGGTGCTACTTCGATAATT
AAAGATGGGGAAAAGTTAACTCTAGATCCCCAGAGGGGTCTGGTATACCACGGTTCTGCTAAAGTTTTATAA

Protein sequence :
MKRTKIVCTIGPASNDVGILKEMIISGMNVARINFAHGSHEEHRERIEKVRRASLEVGIPVAILIDTKGPEIRIGKVENG
KIVLKEGDLVVFDPDIAEGQGLRVPVNYPGLARDVNVGGTILLDDGLIELKIEDIQGNKVIARVITGGELSNNKGVNLPG
VKVNLPALTEKDRKDIDFGIEIGADFIAHSFVRKAADVLALRRYLEEKGADMEIIAKIENQEGVENIDEIIKVADGIMVA
RGDLGVEIPTEDVPLVQKEIIEKCNKNGKPVITATQMLDSMIRNKRPTRAEATDVANAIFDGTDAVMLSGETAAGKYPVE
AVKTMARIAEKAEEKLLTLRKLNKPTTKSFKTVTDAISHASVTTAEELDAGAIITPTSSGYTARMVSRYRPAVPIIAATP
DMKVLRKLTLVWGVFPLLVKTSDSTDEMLSKAIEASLESGLLKPGDLVVLTAGVPVGVKGTTNLLKVHVAGNVLAKGVGI
GTRPITGTARVCRTAREAIERIQPGDILVTEATDRDFVSAIEKAAGLVVEAGGLTSHAAIAGLEFGIPVIVGVDGATSII
KDGEKLTLDPQRGLVYHGSAKVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-103 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-104 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-104 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-104 51
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 4e-66 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_359989.1 pyruvate kinase VFG0479 Protein 1e-104 51