Gene Information

Name : cvrA; nhaP2; ycgO (Pfl01_0446)
Accession : YP_346179.1
Strain : Pseudomonas fluorescens Pf0-1
Genome accession: NC_007492
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 506031 - 507773 bp
Length : 1743 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGAATGCGACGACCATCAACAGCCTGTTCTTGATCGGCGCGTTGCTGGTAGGCGCAAGCATTCTTGTCAGCTCCCTGTC
TTCCCGTCTCGGCATCCCGATTCTGGTGATCATTCTCGCGGTCGGCATGAGTGCCGGGGTCGATGGCGGCGGCATCATTT
TCGATAACTACCCGACGGCCTATCTGGTCGGCAACCTCGCACTGGCAGTGATCCTGCTCGACGGTGGCTTGCGCACCCGG
GTGTCCAGTTTCCGCGTGGCGTTGTGGCCGGCCTTGTCGCTGGCCACGGTCGGTGTCCTTATCACCACCGGCCTCACCGG
CATGGCCGCCGCGTGGCTGTTTGATCTCAATCTGATCCAAGGCCTGCTGATCGGCGCTATCGTCGGTTCCACGGACGCCG
CGGCGGTGTTCTCGCTGCTCGGCGGAAAGGGCCTGAACGAACGGGTGACCGCCAGCCTGGAAATCGAATCCGGCAGCAAC
GACCCGATGGCGGTGTTCCTCACCGTGACCCTGATCGACATGCTCGCCAGCGGCCAGACCGGTCTGCACTGGAGCCTGCT
GACCCACCTGATCCGCGAGTTTGGCATTGGCGGTGTGATCGGCCTGGGTGGCGGCTGGCTGATGCTGCAACTGGTCAACC
GGATCAACCTGGCCACCGGTCTGTATCCGATTCTGGTGATCGCCGGCGGGCTGGTGGTGTTCGCCCTGACCAACGCCCTG
CACGGCAGCGGTTTCCTCGCCGTGTACCTGTGCGGTCTGGTGATCGGCAACCGCCCGGTGCGCAGCCGTCATGGCATTCT
GCACATGCTCGACGGCATGGCGTGGCTGGCGCAGATCGGCATGTTCCTGGTGCTGGGCCTGCTGGTCACCCCGCATGACT
TGCTGCCGATCGCCCTGCCTGCGCTGGGTCTGGCGCTGTGGATGATTCTGTTCGCTCGGCCGCTATCGGTGCTGGTCGGG
CTGCTGCCGTTCAAGGCCTTCCATGGCCGCGAAAAGGCGTTCATTTCCTGGGTCGGCCTGCGTGGCGCGGTGCCGATCAT
TCTGGCGGTGTTCCCGCTGATGGCCGGGCTGCCGAATGCGCAGCTGTACTTCAACCTCGCGTTCTTCATCGTGCTGGTGT
CGCTGCTGGTGCAGGGCACGAGCCTGCCGTGGGTGGCCAAGCTGCTCAAAGTGACGGTACCGCCGGAGCCGGCGCCGATT
TCCCGCGCCGCCCTCGAAGTGCACGTCACCAGCGAGTGGGAACTGTTCGTTTACAAGCTCGGCGCGGAAAAATGGTGCAT
CGGTTCGCCCCTGCGCGAACTGAAAATGCCCGAAGGCACCCGTATCGCCGCCCTGTTTCGCGGTCAGCAACTGCTCCATC
CGTCGGGTAGTACGGTGCTGGAAGTCGATGATTTGCTGTGTGTCATCGGCCATGAGCACAACCTGCCGGCCCTCGGAAAA
CTGTTCAGCCAGGCGCCGCAACGCGGCCTCGATCTGCGCTTCTTCGGCGATTTCGTACTCGAAGGAGACGCCCAGCTCAA
AGCGGTTGCCGCCCTGTACGGCCTGCCGGCCGAAGGCATCGATCCAGACATGACCCTGGGCCACTTCATTGCCCAGAAAG
TCGGCGGTGCACCGATCGTTGGCGACCAGGTGGAATGGAACAACACCCACTGGACGGTTGCGGTCATGGACGGGAACAAG
ATCGGCAAAGTGGGCGTCAGATTCCCCGAAGGAAGTCGCCCGGGCCCCGGGCTCTTCCTCTAA

Protein sequence :
MNATTINSLFLIGALLVGASILVSSLSSRLGIPILVIILAVGMSAGVDGGGIIFDNYPTAYLVGNLALAVILLDGGLRTR
VSSFRVALWPALSLATVGVLITTGLTGMAAAWLFDLNLIQGLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSN
DPMAVFLTVTLIDMLASGQTGLHWSLLTHLIREFGIGGVIGLGGGWLMLQLVNRINLATGLYPILVIAGGLVVFALTNAL
HGSGFLAVYLCGLVIGNRPVRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIALPALGLALWMILFARPLSVLVG
LLPFKAFHGREKAFISWVGLRGAVPIILAVFPLMAGLPNAQLYFNLAFFIVLVSLLVQGTSLPWVAKLLKVTVPPEPAPI
SRAALEVHVTSEWELFVYKLGAEKWCIGSPLRELKMPEGTRIAALFRGQQLLHPSGSTVLEVDDLLCVIGHEHNLPALGK
LFSQAPQRGLDLRFFGDFVLEGDAQLKAVAALYGLPAEGIDPDMTLGHFIAQKVGGAPIVGDQVEWNNTHWTVAVMDGNK
IGKVGVRFPEGSRPGPGLFL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 2e-149 66
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 2e-149 66