Gene Information

Name : Pfl01_4173 (Pfl01_4173)
Accession : YP_349901.1
Strain : Pseudomonas fluorescens Pf0-1
Genome accession: NC_007492
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 4711200 - 4711964 bp
Length : 765 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGACCACCGCCTTCACCGTTGTCATCCCGTCGCGTTACGCCTCGACCCGTCTGCCGGGCAAGCCGCTGCTGGACATCGC
CGGCAAGCCGATGATCCAGCACGTCTGGGAGCAGGCGAGCAAAAGCAGCGCCAGCCGTGTGGTGGTGGCGACCGACGATG
CGCGGATTGTCGAGGCCTGCAAGGCCTTCGGCGCCGAAGTGGTGCTGACCCGTGAAGATCACAACTCCGGCACCGATCGT
CTGGCTGAAGTGGCTGCCAAGCTGGGTCTGGAGCCGGATGCCATCGTGGTCAACGTGCAGGGTGACGAACCGCTGATCCC
GCCGAGCGTGATCGATCAGGTCGCCGCCAACCTCGCGGCCCACACCGAAGCGCGCATGGCCACCTTGGCCGAGCCGATCG
AAGACGTGGAAACCTTGTTCAACCCGAACGTGGTCAAGGTCGTCAGCGACCTCAACGGTCTGGCGCTGACCTTCAGTCGC
GCGACCCTGCCATTGGCTCGCGATGCGTTCGCCAAGCGCCGCGACGTGCTGCCGGAAGGCGTACCGTATCGTCGCCACAT
CGGCATCTATGCCTACCGCGCCGGTTTCCTTCAGGACTTTGTGAGCTGGGGCCCGTGCTGGCTGGAAAACACCGAATCCC
TCGAACAACTGCGTGCCCTGTGGCACGGCGTGCGGATTCATGTGGCGGACGCGTTGATCGCGCCGCCGACCGGGGTCGAC
ACCGCCGAAGACCTCGAGCGCGTCCGTCGCCTGCTGGAGGCCTGA

Protein sequence : 
MTTAFTVVIPSRYASTRLPGKPLLDIAGKPMIQHVWEQASKSSASRVVVATDDARIVEACKAFGAEVVLTREDHNSGTDR
LAEVAAKLGLEPDAIVVNVQGDEPLIPPSVIDQVAANLAAHTEARMATLAEPIEDVETLFNPNVVKVVSDLNGLALTFSR
ATLPLARDAFAKRRDVLPEGVPYRRHIGIYAYRAGFLQDFVSWGPCWLENTESLEQLRALWHGVRIHVADALIAPPTGVD
TAEDLERVRRLLEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-38 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-38 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-38 44