Gene Information

Name : murD (Noc_2863)
Accession : YP_344839.1
Strain : Nitrosococcus oceani ATCC 19707
Genome accession: NC_007484
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 3242179 - 3243540 bp
Length : 1362 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
GTGTTGAATGAACCCCTACAGCCCCAAGTGGCGGCAACTAGCGTGATTCTTGGTCTCGGCAAAACCGGACTATCTAGTGC
CCGCTTCCTAGCTAGCCGCGGCTTCTCGATAGCAGTCATGGACAGTCGTAAGTCCCCGCCAGGACTGGCTGCCCTCCAGG
AGCAAAATCCTGATGCGGTGCTCCGGCTGGGTGGTTTTGATGCTGCCCTGATAGCGGAGGCCGAACAATTGGTCGTCAGT
CCTGGCGTAGCCTTGAGTGAGCCAGCAATCCTGGCAGCTCGGGCAAGAGGAATACCTGTGGTAGGGGATATTGAATTATT
TGCTTCCTATGTCAAGGCGCCCGTGATAGGGATCACCGGCTCTAATGGTAAAAGCACTGTGACCTCGCTTCTTGAAGCGA
TGGCGCGCCAGGCAGGCAGGCAGGTACTCGCGGGTGGCAATTTGGGAACCCCCGCCTTGGAATTGCTAGAAAAGCCGGTG
CCGGATCTTTATATCCTGGAATTATCCAGCTTTCAATTGGAAACTACGTATACCCTAGATGCCGTTGCTGCTTGCGTCCT
TAATATCAGTCCCGATCATATGGATCGATACCCCGATCTAGATGCCTATTGTCAGGCGAAAGCCAGAATTTACCGGGGGA
CTGGGACGATGGTTATTAACGCCGATGATTTTCGTGTGGCAAGCCTCGTCCAACCCCATCGGCCTTGCCTTCGATTTACC
TTGGGGATGCCGGCTGTTGATGAATACGGCTTACAAGAGCGGGCCGGTGAAACTTGGCTGGTCCGCGGCCATGAGCGGCT
GCTATCGGCTCGGCGGTTACCTTTAGCTGGGCGCCATAATCTAGCCAATGCCTTGGCCGCGCTGGCGCTGGGGGAGGCCG
TGGGATTGCCTCGCGCTGCGATGTTGTCGGCTTTACAGGCATTCTCCGGTTTACCTCACCGTTGCGAGTGGTTGGCAGAG
GTAAACGGGGTGCGCTGGTACAACGACTCCAAAGGAACCAATGTAGGTGCCACGGTAGCTGCGATTGAAGGAATTCCCTG
CCAAGGCAAGCTGATACTTATTGCAGGAGGTGTCGGCAAGGGCGCGGATTTTTCTCCTTTATCCAAGCCTTTGATCCAGC
GGGCCAGGGCAGTTGTCTTGATGGGTCAAGATGCTTCCCGGTTGGAAGCGGTGTTAGCCAGTGGCCCCCCCCTCTATCGG
GTTAATAGCATGGATGAGGCGGTGGTTAAAGCGAATGTCTTGGCCCAATCTGGTGATTGCGTCCTGTTATCGCCTGCCTG
CGCTAGCTTCGATATGTATGCTGATTTTGAAGCTCGCGGTCAAGCGTTTAGGCAAGCTGTACGGGAGATCTTGTCATGTT
GA

Protein sequence :
MLNEPLQPQVAATSVILGLGKTGLSSARFLASRGFSIAVMDSRKSPPGLAALQEQNPDAVLRLGGFDAALIAEAEQLVVS
PGVALSEPAILAARARGIPVVGDIELFASYVKAPVIGITGSNGKSTVTSLLEAMARQAGRQVLAGGNLGTPALELLEKPV
PDLYILELSSFQLETTYTLDAVAACVLNISPDHMDRYPDLDAYCQAKARIYRGTGTMVINADDFRVASLVQPHRPCLRFT
LGMPAVDEYGLQERAGETWLVRGHERLLSARRLPLAGRHNLANALAALALGEAVGLPRAAMLSALQAFSGLPHRCEWLAE
VNGVRWYNDSKGTNVGATVAAIEGIPCQGKLILIAGGVGKGADFSPLSKPLIQRARAVVLMGQDASRLEAVLASGPPLYR
VNSMDEAVVKANVLAQSGDCVLLSPACASFDMYADFEARGQAFRQAVREILSC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 9e-79 49
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 9e-79 49