Gene Information

Name : cusR (PSHAb0012)
Accession : YP_341509.1
Strain :
Genome accession: NC_007482
Putative virulence/resistance : Virulence
Product : transcriptional activator of copper resistance (two-component regulatory system with CusS)
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 16187 - 16873 bp
Length : 687 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11004187, 8449873; Product type r : regulator

DNA sequence : 
ATGCGCATACTAATCGTTGAAGACGAGATTAAAACCGGTGATTACTTAAAACAGGGCTTAACCGAAGCCGGCTTTCAGGT
TTGTTTGGCGCGCAATGGCCTTGACGGTCACCATTTAGCAATGACCGAATTATTTGATGTGATTATATTAGATATAATGT
TGCCCGATGTATCTGGCTGGCGAATTTTAGAGTCGGTACGAGAAGCCAAAAACGACACGCCAGTATTATTTTTATCGGCT
CGCGATAGTGTTGATGACAGAGTAAAAGGGCTTGAACTTGGCGCAGATGATTACTTAATAAAACCGTTTGCTTTTTCAGA
AGTACTTGCCCGCGTACGTACGCTTATTCGCCGTGGTGGCGTGCAAAAAGTGGCCGACATACTCACGATTGCAGACTTAG
AAATGGATATACCAAAGCGTAAAATACAGCGAGCAGGCAAGCGTATTTTGCTCAGTAATAAAGAGTTTAGCTTATTAGAG
CTACTACTGCGCCGAGAAGGCGAAGTGCTATCTCGCTCACTTATAGCGTCGCAAGTATGGGATATGAACTTTGAAAGTGA
TACCAATGTAATAGATGTTGCGATTAGACGCCTGCGGGGCAAGGTTGACGATGAGTATAGTATTAAACTTATTCATACAG
TGCGCGGTATGGGCTATAAATTAGAGGTCGAAAATGCCCAAAATTAA

Protein sequence : 
MRILIVEDEIKTGDYLKQGLTEAGFQVCLARNGLDGHHLAMTELFDVIILDIMLPDVSGWRILESVREAKNDTPVLFLSA
RDSVDDRVKGLELGADDYLIKPFAFSEVLARVRTLIRRGGVQKVADILTIADLEMDIPKRKIQRAGKRILLSNKEFSLLE
LLLRREGEVLSRSLIASQVWDMNFESDTNVIDVAIRRLRGKVDDEYSIKLIHTVRGMGYKLEVENAQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-48 56
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-47 55

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cusR YP_341509.1 transcriptional activator of copper resistance (two-component regulatory system with CusS) BAC0197 Protein 2e-53 64
cusR YP_341509.1 transcriptional activator of copper resistance (two-component regulatory system with CusS) BAC0111 Protein 7e-59 63
cusR YP_341509.1 transcriptional activator of copper resistance (two-component regulatory system with CusS) BAC0638 Protein 2e-58 63
cusR YP_341509.1 transcriptional activator of copper resistance (two-component regulatory system with CusS) BAC0083 Protein 7e-56 62
cusR YP_341509.1 transcriptional activator of copper resistance (two-component regulatory system with CusS) BAC0308 Protein 3e-51 62
cusR YP_341509.1 transcriptional activator of copper resistance (two-component regulatory system with CusS) BAC0347 Protein 1e-52 61
cusR YP_341509.1 transcriptional activator of copper resistance (two-component regulatory system with CusS) BAC0125 Protein 2e-51 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cusR YP_341509.1 transcriptional activator of copper resistance (two-component regulatory system with CusS) VFG0596 Protein 5e-49 56
cusR YP_341509.1 transcriptional activator of copper resistance (two-component regulatory system with CusS) VFG1389 Protein 4e-26 43