Gene Information

Name : guaA (BURPS1710b_2546)
Accession : YP_333938.1
Strain :
Genome accession: NC_007434
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2824935 - 2826578 bp
Length : 1644 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGTTCCTTTCCCCGTCCGCTGCCATGCACGACAAAATCCTGATTCTCGACTTCGGTTCGCAAGTCACTCAACTGATCGC
GCGGCGCGTCCGCGAAGCGCACGTCTACTGCGAGATCCATCCGAACGACGTTTCCGACGACTTCGTTCGCGAGTTCGCCC
CGAAGGGCGTGATTCTGTCCGGCAGCCACGCGAGCACCTACGAGGACCACCAGTTGCGCGCGCCGCAGGCGGTATGGGAT
CTCGGCGTGCCCGTGCTCGGCATTTGCTACGGGATGCAGACGATGGCCGTACAACTGGGCGGCAAGGTCGAGTGGAGCGA
CCACCGCGAGTTCGGCTATGCGGAAGTGCGCGCGCATGGCCGCACGCGCCTGCTCGACGGCATCCAGGATTTCGCGACGC
CCGAAGGCCACGGGATGCTGAAGGTCTGGATGAGCCACGGCGACAAGGTCGGCGAGATGCCGCCGGGCTTCGCGCTGATG
GCGTCGACGCCGAGCTGCCCGATCGCCGGCATGGCCGACGAGGCGCGCGGCTACTACGCGGTGCAGTTCCACCCGGAAGT
CACGCACACGGTGCAGGGCCGCAAGCTGCTCGAGCGCTTCGTGCTCGACATCGCCGGCGCGAAACCCGACTGGATCATGC
GCGACCACATCGAGGAGGCGGTCGCGCGGATTCGCGAGCAGGTCGGCGACGAGGAAGTGATCCTCGGCCTGTCGGGCGGC
GTGGATTCGAGCGTCGCGGCGGCGCTCATCCACCGTGCGATCGGCGATCAATTGACTTGCGTGTTCGTCGACCACGGCCT
GCTGCGCCTGAACGAAGGCAAGATGGTGCTCGACATGTTCGAAGGCCGGCTGCATGCGAAGGTCGTCCACGTCGACGCGT
CCGAGCAGTTCCTCGGCCATCTCGCGGGCGTCGCCGATCCGGAGCACAAACGCAAGATCATCGGCCGCGAGTTCGTCGAA
GTGTTCCAGGCGGAAGCGAAGAAGCTGACGAACGCGAAGTGGCTCGCGCAGGGGACGATCTACCCGGACGTGATCGAATC
GGGCGGCGCGAAGACGAAGAAGGCGACGACGATCAAGAGCCATCACAACGTGGGCGGCTTGCCGGAGACGCTCGGCCTGA
AGCTGCTCGAGCCGCTGCGCGATCTGTTCAAGGACGAAGTGCGCGAGCTTGGCGTCGCGCTCGGCTTGCCGGCGGAGATG
GTGTATCGCCATCCGTTCCCGGGCCCGGGCCTCGGCGTGCGGATTCTGGGCGAAGTGAAGCGCGACTACGCGGAGCTGCT
GCGCCGCGCGGATGCGATCTTCATCGAAGAGCTCTGCGGGACGCTCGCGACCGAGCAGGATGCGGCGGCGGGCCTGTGCG
AGCCGTCGCAGGTCGGCAAGAGCTGGTACGACCTGACGAGCCAGGCGTTCGCGGTGTTCCTGCCGGTGAAGTCGGTCGGC
GTGATGGGCGACGGCCGCACGTACGACTACGTGGCCGCGTTGCGCGCGGTGCAGACGACCGATTTCATGACGGCGCACTG
GGCGCATCTGCCGTATGCGCTGCTCGGCCGCGCGTCGAACCGGATCATCAACGAAGTGCGCGGGATCAATCGGGTGGTGT
ACGACGTGTCGGGTAAGCCGCCGGCGACAATCGAGTGGGAGTGA

Protein sequence :
MFLSPSAAMHDKILILDFGSQVTQLIARRVREAHVYCEIHPNDVSDDFVREFAPKGVILSGSHASTYEDHQLRAPQAVWD
LGVPVLGICYGMQTMAVQLGGKVEWSDHREFGYAEVRAHGRTRLLDGIQDFATPEGHGMLKVWMSHGDKVGEMPPGFALM
ASTPSCPIAGMADEARGYYAVQFHPEVTHTVQGRKLLERFVLDIAGAKPDWIMRDHIEEAVARIREQVGDEEVILGLSGG
VDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGKMVLDMFEGRLHAKVVHVDASEQFLGHLAGVADPEHKRKIIGREFVE
VFQAEAKKLTNAKWLAQGTIYPDVIESGGAKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVALGLPAEM
VYRHPFPGPGLGVRILGEVKRDYAELLRRADAIFIEELCGTLATEQDAAAGLCEPSQVGKSWYDLTSQAFAVFLPVKSVG
VMGDGRTYDYVAALRAVQTTDFMTAHWAHLPYALLGRASNRIINEVRGINRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-117 49
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-117 49
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-117 49
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-106 47