Gene Information

Name : leuS (SAK_1995)
Accession : YP_330587.1
Strain : Streptococcus agalactiae A909
Genome accession: NC_007432
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1987441 - 1989942 bp
Length : 2502 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACATTCTATAATCACAAAGAAATCGAACCCAAATGGCAAGCCTTTTGGGCAGATAATCATACTTTTAAAACAGGAAC
AGATGCATCAAAACCTAAGTTTTATGCCCTAGATATGTTCCCATACCCATCTGGAGCTGGTCTCCACGTTGGTCACCCAG
AAGGCTATACAGCAACTGATATTCTCAGCCGTTTCAAACGTGCCCAAGGTCACAATGTCCTCCACCCAATGGGTTGGGAT
GCCTTTGGACTTCCTGCTGAGCAGTACGCTATGGATACTGGTAATGACCCAGCCGAGTTTACAGCTGAAAACATCGCTAA
CTTTAAGCGCCAGATTAACGCTCTTGGCTTCTCATACGACTGGGATCGCGAAGTCAACACAACTGACCCTAACTACTACA
AGTGGACACAGTGGATCTTTACTAAGCTTTATGAAAAAGGCCTAGCCTATGAAGCTGAAGTTCCCGTTAACTGGGTTGAA
GAATTGGGAACGGCCATCGCCAACGAAGAGGTTCTTCCAGATGGCACATCAGAACGTGGCGGCTACCCAGTTGTCAGAAA
ACCAATGCGCCAATGGATGCTCAAAATCACTGCCTATGCAGAGCGCTTGCTAGAAGACTTGGAAGAAGTTGACTGGCCAG
AATCAATTAAGGACATGCAACGCAACTGGATTGGTAAATCAACTGGTGCCAATGTAACCTTCAAGGTTAAGGATACAGAT
AAGGACTTCACTGTCTTCACAACACGTCCTGACACCCTTTTTGGTGCAACTTACGCAGTTCTTGCTCCTGAACATGCCTT
GGTTGATGCTATTACAACAGCTGACCAAGCAGAAGCTGTTGCCGAATACAAACGTCAAGCAAGTCTTAAATCAGATCTTG
CCCGTACAGACCTTGCTAAAGAAAAAACAGGTGTCTGGACAGGTGCCTATGCTATTAACCCAGTTAATGGTAAAGAAATT
CCAGTTTGGATTGCGGACTATGTCCTTGCCAGCTACGGTACAGGTGCTATCATGGCTGTTCCAGCCCACGATGAACGTGA
CTGGGAATTCGCAAAACAATTTAAGCTAGACATCATTCCAGTTCTTGAAGGTGGTAATGTTGAAGAGGCTGCCTTTACAG
AAGACGGTCTTCACATCAACTCAGACTTCCTAGATGGTCTCGATAAAGCGTCAGCTATTGCCAAAATGGTCGAATGGCTT
GAAGCAGAAGGTGTTGGTAATGAGAAAGTCACTTACCGTCTCCGCGACTGGCTCTTCAGCCGTCAACGTTACTGGGGTGA
GCCAATCCCAATCATCCACTGGGAAGATGGGACATCAACAGCGGTTCCTGAGAGTGAATTGCCACTGGTTCTTCCAGTAA
CCAAGGATATCCGTCCTTCAGGTACTGGTGAGAGCCCACTTGCTAACTTGACAGACTGGTTGGAAGTGACTCGTGAAGAT
GGTGTTAAAGGTCGTCGTGAGACTAACACCATGCCACAATGGGCAGGTTCAAGCTGGTACTATCTCCGTTACATTGATCC
ACACAACACCGAAAAACTGGCTGATGAGGAACTTCTCAAACAATGGTTGCCAGTTGATATCTATGTCGGTGGTGCAGAGC
ATGCCGTGCTTCACCTTCTCTACGCTCGCTTCTGGCACAAGGTTCTTTACGATCTCGGTGTCGTACCTACCAAAGAGCCA
TTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACAAGCTACCGCGACAGCCGTGGTGCACTTGTGGCAACTGACAA
GGTTGAAAAACGTGATGGTAGCTTCTTCCATGTGGAAACTGGGGAAGAGCTTGAACAAGCACCAGCTAAGATGTCTAAAT
CACTTAAGAACGTTGTCAACCCAGATGATGTTGTTGAACAGTACGGTGCTGACACCCTTCGTGTTTACGAGATGTTCATG
GGACCACTTGACGCTTCAATCGCTTGGTCTGAGGAAGGTCTTGAAGGCTCACGTAAGTTCTTGGACCGTGTTTACCGTTT
GATCACGACTAAAGAGATTACTAAGGAAAATAGCGGAGCCCTTGACAAGGTTTACAACGAAACCGTTAAGGCTGTTACTG
AGCAAGTTGACCAAATGAAATTCAACACAGCTATCGCTCAGCTCATGGTCTTTGTCAATGCAGCTAACAAGGAAGACAAA
CTCTTTAGCGACTATGCCAAAGGCTTTGTTCAATTGATTGCACCATTCGCACCACACTTAGGTGAGGAGCTCTGGCAAGT
CTTGACAGCCTCAGGTGAGTCAATCTCTTACGTGCCATGGCCAAGCTATGACGAAAGTAAATTGGTTGAAAACGAAATTG
AAATCGTTGTCCAAATCAAAGGTAAGGTCAAAGCTAAACTTGTAGTTGCTAAAGACCTTTCACGCGAAGAATTACAAGAT
CTTGCCCTTGCTAACGAAAAAGTCCAATCCGAAATCGCTGGCAAAGACATCATCAAAGTCATCGCAGTACCAAACAAACT
GGTTAATATTGTGGTGAAATAA

Protein sequence :
MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWD
AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD
KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEI
PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWL
EAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED
GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP
FQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM
GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITKENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK
LFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDESKLVENEIEIVVQIKGKVKAKLVVAKDLSREELQD
LALANEKVQSEIAGKDIIKVIAVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 98