Gene Information

Name : panE (SAK_1382)
Accession : YP_329992.1
Strain : Streptococcus agalactiae A909
Genome accession: NC_007432
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 1369023 - 1369946 bp
Length : 924 bp
Strand : -
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGTTAGTTTATATTGCTGGTTCAGGCGCTATGGGATGTCGTTTTGGATATCAAATTTCTAAAACAAATCATGATGTTAT
TTTACTTGATAATTGGGCAGACCATATTATGGCTATTAAAGAAAATGGCTTGAAGGTAACAGGTGATACAGAGGACCTTG
TTAAACTTCCTATCATGAAGCCAACTGATGCGACAGAAGAAGCAGATTTAATTATTTTGTTTACTAAAGCAATGCAGTTG
CCAAATATGCTTCAAGATATTAAAAAAATTATTGGTAAGAAAACAAAGGTCTTATGTCTTTTAAATGGATTAGGACATGA
AGATGTCATTCGTCAATATATCCCTGAACACAATATTTTGATGGGAGTAACAGTTTGGACTGCAGGGTTGAAAGGACCAG
GGCATGCTCATCTGGAAGGAGTTGGTTCTGTAAATCTTCAAAGTATCGATCCTAACAATCAAGAAGCAGGTCATCGCGTT
ACTGAATTGCTTAATGAAGCAAAATTACAGGCTACTTATGACGAAAATGTTTTGCCAAATATTTGGAGAAAAGCTTGTGT
TAACGGAACGATGAATTCAACTTGCGCCTTGCTAGATTGTACAATTGGTCAACTCTTTGCTAGTGAAGACGGCGTAAATA
TGGTACATGAAATTATCCATGAATTTGTTACTGTTGGAAAAGCAGAAGGTGTAGAGCTTGATGAAGAAGAAATAACAAAG
TACGTTATGGATACATCTGTTAAAGCAGCCCATCATTACCCTTCAATGCATCAAGACTTAGTTCAAAATCAGCGCTTAAC
TGAAATTGATTTCTTAAATGGCGCAGTGAATAAAAAAGGTGAAAACCTAGGCATTGATACACCTTACTGTCGATTAATCA
CACAATTAATTCACACTAAAGAAAATGTACTTAGCATAAAATAA

Protein sequence :
MLVYIAGSGAMGCRFGYQISKTNHDVILLDNWADHIMAIKENGLKVTGDTEDLVKLPIMKPTDATEEADLIILFTKAMQL
PNMLQDIKKIIGKKTKVLCLLNGLGHEDVIRQYIPEHNILMGVTVWTAGLKGPGHAHLEGVGSVNLQSIDPNNQEAGHRV
TELLNEAKLQATYDENVLPNIWRKACVNGTMNSTCALLDCTIGQLFASEDGVNMVHEIIHEFVTVGKAEGVELDEEEITK
YVMDTSVKAAHHYPSMHQDLVQNQRLTEIDFLNGAVNKKGENLGIDTPYCRLITQLIHTKENVLSIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 3e-72 49
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 4e-72 49