Gene Information

Name : clpL (SAK_1336)
Accession : YP_329946.1
Strain : Streptococcus agalactiae A909
Genome accession: NC_007432
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpL
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1320422 - 1322530 bp
Length : 2109 bp
Strand : +
Note : identified by similarity to SP:Q06716; match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF07724

DNA sequence :
ATGGCAAATAATAATTTTTATAATCGTGACCCTTTTGGAAATATGGATGATATTTTTAATTCTCTAATGGGAAATATGGG
GGGCTATAATAGTGAGAATAAACGATACTTAATCAATGGACGGGAAGTTACTCCTGAAGAATTCAGTCAATATCGTCAAA
CTGGAAAACTCCCCGGTCAAGAGCTAAATAACCAAAATACTCCTACAAACCAAGTCTCTGCAGATAGTGTTTTGACTAAA
TTAGGAACTAATTTAACCGATCAAGCACGTCAGCATTTGCTAGATCCAGTTATTGGACGAAACAAAGAAATTCAGGAAAC
TGCAGAAATTCTAGCTCGTCGTACTAAAAATAATCCTGTTCTAGTTGGTGATGCAGGTGTTGGTAAAACAGCTGTTATTG
AAGGTTTGGCACAAGCAATTATAAATGGTGATGTCCCTGCTGCTATCAAAAATAAAGAAATCATTTCGATAGATATCTCT
AGCCTTGAAGCTGGCACCCAATATAGGGGTAGTTTTGAAGAAAATATTCAAAATATCATAAAAGAAGTTAAGGAAACAGG
AAATATTATTCTCTTCTTTGATGAAATACACCAAATATTAGGAGCCGGTTCAACTGGTGGTGATAGTGGCTCTAAGGGGC
TCGCAGATATACTTAAGCCTGCACTTTCACGTGGTGAATTAACGGTTATAGGTGCAACTACTCAAGATGAATATCGTAAC
ACCATTCTCAAGAATGCTGCCTTAGCACGCCGCTTTAACGAAGTTAAAGTCAATGCACCTTCTGCACAAGATACTTTCAA
TATCCTTATGGGGATAAGAAACCTCTATGAGCAACATCATAATGTTGTTTTACCTGACTCTGTTTTGAAAGCAGCTGTAG
ATTTATCTATTCAATACATACCACAAAGAAGTCTCCCTGATAAAGCAATTGACCTTATTGATATGACTGCTGCACACCTA
GCTGCGCAACATCCCGTAACTGACCTTAAATCCTTAGAAAAAGAAATCGCTGCGCAAAGAGACAAGCAAGAAAAAGCTGT
CAATACTGAAGATTTTGAAGAAGCTCTTAAGGTCAAGACACGCATTGAAGAGTTACAAAACCAGATTGATAATCATACCG
AAGGACAAAAAGTCACTGCAACTATCAATGATATCGCTATGTCAATTGAGCGTCTAACTGGAGTTCCTGTATCAAATATG
GGTGCTAGTGATATTGAACGCTTAAAAGAACTTGGCAATCGTCTAAAAGGTAAAGTCATTGGTCAAAATGATGCTGTTGA
GGCAGTTGCAAGAGCTATTCGCCGAAATCGTGCTGGTTTCGATGATGGTAATCGTCCGATTGGTAGCTTTCTATTTGTTG
GACCAACTGGAGTTGGTAAAACTGAGCTAGCAAAGCAATTAGCTTTTGATATGTTCGGATCAAAGGATGCTATCGTTAGA
CTTGATATGTCTGAATATAATGATCGTACTGCAGTTTCTAAGCTAATTGGAGCGACTGCTGGTTACGTTGGTTATGACGA
CAATAGTAATACACTAACAGAACGTATCCGTCGAAATCCTTATTCTATTGTTCTTCTTGATGAAATCGAAAAAGCTGACC
CGCAAGTTATCACGCTTCTCCTTCAAGTTCTAGATGATGGTCGTTTAACTGATGGTCAAGGAAACACTATTAACTTTAAA
AATACTGTTATCATTGCAACCTCAAATGCAGGTTTTGGAAACGAAGCATTTACAGGTGACAGCGATAAAGACTTGAAAAT
TATGGAACGAATTTCTCCATATTTCCGTCCAGAATTTCTAAATCGTTTCAATGGTGTTATTGAATTCTCTCACCTAAGCA
AAGATGACTTAAACGAAATTGTAGATTTGATGCTTGATGAAGTTAACCAAACAATTGGCAAAAAAGGAATTGACCTTGTG
GTAGATGAAAATGTTAAATCACACTTAATTGACCTGGGTTATGACGAAGCAATGGGAGTACGTCCATTGCGCCGTGTCAT
CGAGCAAGAAATTCGAGATCGCATCACAGACTACTATCTCGATCATACAGATGTTAAACACCTAAAAGCTAATTTGCAAG
ATGGCCAAATCGTCATTTCTGAAAGATAA

Protein sequence :
MANNNFYNRDPFGNMDDIFNSLMGNMGGYNSENKRYLINGREVTPEEFSQYRQTGKLPGQELNNQNTPTNQVSADSVLTK
LGTNLTDQARQHLLDPVIGRNKEIQETAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIINGDVPAAIKNKEIISIDIS
SLEAGTQYRGSFEENIQNIIKEVKETGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAQDTFNILMGIRNLYEQHHNVVLPDSVLKAAVDLSIQYIPQRSLPDKAIDLIDMTAAHL
AAQHPVTDLKSLEKEIAAQRDKQEKAVNTEDFEEALKVKTRIEELQNQIDNHTEGQKVTATINDIAMSIERLTGVPVSNM
GASDIERLKELGNRLKGKVIGQNDAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAFDMFGSKDAIVR
LDMSEYNDRTAVSKLIGATAGYVGYDDNSNTLTERIRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFK
NTVIIATSNAGFGNEAFTGDSDKDLKIMERISPYFRPEFLNRFNGVIEFSHLSKDDLNEIVDLMLDEVNQTIGKKGIDLV
VDENVKSHLIDLGYDEAMGVRPLRRVIEQEIRDRITDYYLDHTDVKHLKANLQDGQIVISER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-132 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpL YP_329946.1 ATP-dependent Clp protease ATP-binding subunit ClpL VFG0080 Protein 8e-155 48
clpL YP_329946.1 ATP-dependent Clp protease ATP-binding subunit ClpL VFG0079 Protein 6e-138 43