Gene Information

Name : lcrD (CTA_0095)
Accession : YP_327889.1
Strain : Chlamydia trachomatis A/HAR-13
Genome accession: NC_007429
Putative virulence/resistance : Virulence
Product : low calcium response protein D
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 104050 - 106176 bp
Length : 2127 bp
Strand : -
Note : type III secretion inner membrane protein SCTV

DNA sequence :
ATGAACAAGCTACTCAACTTTGTCAGTAGAACATTCGGGGGAGATGCGGCCCTGAATATGATAAACAAGTCCAGTGACCT
GATCCTCGCCATGTGGATGTTAGGCGTGGTCTTGATGATCATTTTGCCATTGCCTCCAGCTATGGTGGACTTTATGATCA
CCATTAACTTGGCGATCTCTGTGTTCCTGCTGATGGTTGCCTTGTATATTCCCAGCGCATTACAACTTTCTGTTTTCCCC
TCCTTACTCTTAATCACCACAATGTTCCGATTGGGGATTAACATTTCTTCCTCCCGACAAATTCTCCTTCATGCTTATGC
TGGTCACGTGATCCAAGCCTTCGGAGACTTCGTCGTTGGAGGAAACTATGTCGTTGGATTTATTATCTTCCTAATCATCA
CCATCATTCAGTTTATCGTGGTAACAAAAGGTGCGGAGAGGGTCGCTGAGGTAGCTGCTCGATTCCGATTAGATGCCATG
CCTGGTAAACAGATGGCCATCGATGCCGACCTACGAGCAGGAATGATTGATGCGACACAAGCTCGTGATAAGCGATCTCA
GATTCAGAAAGAAAGTGAACTTTATGGAGCTATGGACGGAGCCATGAAGTTCATTAAGGGAGACGTGATCGCAGGGATTG
TTATCTCCTTGATTAACATCGTAGGAGGATTAGTCATCGGAGTGACCATGAAGGGCATGACGATGGCTCAAGCCGCGCAC
ATCTACACGTTGATTACGATCGGTGACGGGTTAGTTTCTCAAATCCCCTCTCTGTTAATCTCTTTAACAGCTGGTATCGT
AACCACTCGAGTATCTAGTGATAAAGACACTAACCTTGGTAAGGAAATTTCTAGCCAGTTGGTTAAAGAACCTCGGGCAC
TTCTCCTATCCGCAGGCGCAACCTTAGGAATCGGATTCTTCAAAGGTTTCCCTTTATGGTCATTTGCTTTAATGGCCGTT
CTCTTTGCAGTATTAGGTATTCTGTTAATCACTAAGAAAAACTCTCCAGGGAAAAAAGGCGGAGCCAGCTCTACTACTAC
AGTAGGTGCCGCTGATGGAGCTGCGGCTTCAGGAGAAAATTCTGATGATTATGCTCTGACTCTTCCTGTAATTCTTGAAC
TTGGAAAAGATCTTTCTAAACTCATCCAACAACGAACCAAATCGGGGCAAAGTTTTGTGGATGATATGATTCCTAAAATG
CGTCAGGCTCTCTATCAGGATATTGGAATTCGTTATCCAGGAATCCATGTACGTACAGACTCCCCTTCCTTGGAAGGTAA
TGACTATATGATTCTGCTGAATGAGGTTCCCTACGTTCGCGGAAAAATTCCACCAAATCATGTGTTAACAAATGAAGTAG
AAGAAAACTTATCTCGGTATAACTTACCTTTTATTACTTACAAAAATGCTGCAGGATTGCCTTCCACTTGGGTTAGTACA
GATGCTCTCACTATCTTAGAGAAAGCTGCGATTAAATACTGGTCTCCTTTGGAAGTGATTATTCTTCACTTGTCCTACTT
CTTCCATAGAAATTCTCAAGAGTTCTTAGGCATTCAGGAAGTACGCTCTATGATTGAATTTATGGAACGTTCCTTCCCTG
ATCTTGTTAAAGAGGTTACCCGTCTTATTCCTCTACAGAAGCTTACAGAAATCTTTAAGCGTTTAGTTCAAGAACAAATA
TCCATTAAGGATTTACGAACTATTTTGGAATCTTTGAGCGAATGGGCACAGACGGAAAAAGATACAGTATTACTTACTGA
ATATGTGCGCTCTTCCTTGAAACTCTATATCAGCTTCAAGTTCTCTCAAGGGCAATCCGCTATTTCTGTATATCTGCTCG
ATCCTGAAATTGAAGAGATGATCCGCGGAGCAATCAAACAAACTTCTGCAGGATCTTATTTGGCTTTAGATCCAGATTCT
GTAAACCTCATCTTAAAATCTATGCGGATGACTATTACTCCTACACCTCCTGGAGGACAGCCTCCTGTGCTGTTGACAGC
AATTGATGTCAGACGCTATGTACGGAAATTGATAGAGACAGAATTCCCTGATATCGCTGTGATTTCTTACCAAGAAGTTT
TACCTGAAATTAGAATCCAGCCTTTGGGAAGAATTCAAATTTTCTAA

Protein sequence :
MNKLLNFVSRTFGGDAALNMINKSSDLILAMWMLGVVLMIILPLPPAMVDFMITINLAISVFLLMVALYIPSALQLSVFP
SLLLITTMFRLGINISSSRQILLHAYAGHVIQAFGDFVVGGNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAM
PGKQMAIDADLRAGMIDATQARDKRSQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLVIGVTMKGMTMAQAAH
IYTLITIGDGLVSQIPSLLISLTAGIVTTRVSSDKDTNLGKEISSQLVKEPRALLLSAGATLGIGFFKGFPLWSFALMAV
LFAVLGILLITKKNSPGKKGGASSTTTVGAADGAAASGENSDDYALTLPVILELGKDLSKLIQQRTKSGQSFVDDMIPKM
RQALYQDIGIRYPGIHVRTDSPSLEGNDYMILLNEVPYVRGKIPPNHVLTNEVEENLSRYNLPFITYKNAAGLPSTWVST
DALTILEKAAIKYWSPLEVIILHLSYFFHRNSQEFLGIQEVRSMIEFMERSFPDLVKEVTRLIPLQKLTEIFKRLVQEQI
SIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYISFKFSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDPDS
VNLILKSMRMTITPTPPGGQPPVLLTAIDVRRYVRKLIETEFPDIAVISYQEVLPEIRIQPLGRIQIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lssD AAO18050.1 LssD Virulence TTSS locus Protein 2e-140 46
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 9e-96 42
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-95 41
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 9e-96 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lcrD YP_327889.1 low calcium response protein D VFG2126 Protein 0.0 100
lcrD YP_327889.1 low calcium response protein D VFG0384 Protein 7e-140 46
lcrD YP_327889.1 low calcium response protein D VFG0064 Protein 1e-143 46
lcrD YP_327889.1 low calcium response protein D VFG0198 Protein 1e-129 46