Gene Information

Name : lysS (CTA_0851)
Accession : YP_328609.1
Strain : Chlamydia trachomatis A/HAR-13
Genome accession: NC_007429
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 918960 - 920540 bp
Length : 1581 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTGTAGAAGTTGAATACTTGCAACACGAAGATTATTTGTATAGAACAAGCAAGCTAAAGGAAATCAGAGATTTGGG
CATAAATCCTTACCCTTATCAATACACTGATTGTCTTGAAGTACAGGAAATTCGTAATCAGTTTGTAGATAACGAATTAG
GAGATAGCGAAGCGGCTTTTCGTAAAGAGACACCTAAGGTGCGTTTTGCCGGACGACTTGTTCTTTTCCGTTCTATGGGG
AAAAATTCTTTTGGGCAGATCCTCGATAATGATGCAAAGATTCAAGTGATGTTTAATCGAGATTTTTCTGCAGTGGCAGG
GTTAGCCGCGGATGCTGGGATTTCTCCGATTAAATTTATTGAGAAGAAACTTGATCTAGGAGACATCTTGGGTCTCGAAG
GGTATCTTTTCTTTACTCACTCAGGAGAATTAACGGTTCTCGTTGAAACGGTAACGTTGTTATGTAAATCCTTAATTTCT
TTGCCTGATAAGCATGCAGGATTAGCAGATAAAGAAATTCGCTATCGCAAACGTTGGGCAGATCTGATTTCCTCAGAGGA
TGTGCGTAAGACTTTCTTAACAAGAAGCCGGATTCTTAAGTTGATTCGTGAGTACATGGATCAGCAGAGCTTTTTAGAGG
TGGAAACTCCTATCCTGCAAACCATCTACGGAGGAGCAGAAGCAACTCCTTTTGTTACCACGCTGCAAGCGCTACATGCA
GAAATGTTCCTAAGAATTTCTCTAGAGATTGCTTTGAAAAAACTCCTTGTTGGAGGAATGTCCCGAGTTTATGAAATCGG
CAAAGTTTTCCGTAACGAAGGAATCGATAGAACGCATAATCCAGAGTTTACCATGATAGAGGCTTATGCGGCTTATTGGG
ATTACAATGATGTAATGAAATGTGTGGAAAACCTTGTTGAGTATATCGTACGTGCTTTGAATAACGGGGAAACTCAGGTT
CAGTATTCACATTTAAAATCAGGACCTCAGGTTGTTGATTTTAAAGCTCCATGGATCCGTATGACGATGAAAGAAAGTAT
CTCTGTCTATGGCGGCGTCGATGTAGACTTACATGCAGATCATGAATTACGTAAAATTTTAGAAACACAAACATCTCTTC
CAGAGAAAACGTATGTTCATGCTTCACGAGGAGAGCTGATCGCTTTGCTATTTGATGAGCTGGTTTGTGATAAGCTCATC
GCTCCGCATCACATTACAGATCATCCATTAGAAACAACGCCACTTTGTAAAACATTGCGTTCTGGGGATGAAACTCTGGT
AGAACGATTTGAGAGTTTTTGTTTAGGAAAAGAGTTGTGTAATGCTTATTCGGAACTCAATGATCCTTTACAACAACGAA
AATTGTTGGAAGAGCAAATGCGTAAAAAGGCTTTAAATCCTGACAGCGAATACCATCCTATAGATGAAGAATTTCTAGAA
GCTCTTTGCCAAGGAATGCCTCCTGCAGGAGGATTTGGAATAGGTATCGATCGATTGGTTATGATGTTGACAGACGCCGC
ATCCATTCGGGATGTCCTGTTTTTCCCTGTTATGCGGCGTATAGAAGCAAAAAAAGATTAA

Protein sequence :
MSVEVEYLQHEDYLYRTSKLKEIRDLGINPYPYQYTDCLEVQEIRNQFVDNELGDSEAAFRKETPKVRFAGRLVLFRSMG
KNSFGQILDNDAKIQVMFNRDFSAVAGLAADAGISPIKFIEKKLDLGDILGLEGYLFFTHSGELTVLVETVTLLCKSLIS
LPDKHAGLADKEIRYRKRWADLISSEDVRKTFLTRSRILKLIREYMDQQSFLEVETPILQTIYGGAEATPFVTTLQALHA
EMFLRISLEIALKKLLVGGMSRVYEIGKVFRNEGIDRTHNPEFTMIEAYAAYWDYNDVMKCVENLVEYIVRALNNGETQV
QYSHLKSGPQVVDFKAPWIRMTMKESISVYGGVDVDLHADHELRKILETQTSLPEKTYVHASRGELIALLFDELVCDKLI
APHHITDHPLETTPLCKTLRSGDETLVERFESFCLGKELCNAYSELNDPLQQRKLLEEQMRKKALNPDSEYHPIDEEFLE
ALCQGMPPAGGFGIGIDRLVMMLTDAASIRDVLFFPVMRRIEAKKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_328609.1 lysyl-tRNA synthetase VFG1668 Protein 1e-69 41