Gene Information

Name : tktB (CTA_0819)
Accession : YP_328578.1
Strain : Chlamydia trachomatis A/HAR-13
Genome accession: NC_007429
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 884168 - 886168 bp
Length : 2001 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGCTGGCAATAGTGATTTAGATATAGACATCTTAGAAAAGATTGCAGGAACTATTAAACAGTTGAGCATAGAAAGTAT
TCAGAAAGCATCTTCAGGTCATCCAGGAATGCCTTTAGGATGCGCAGAGCTCGCTGCTTATTTATATGGTTACGTATTGC
GATATAATTCTAAAGATTCTCGATGGGTGAATAGGGATCGCTTTGTTCTCTCTGCTGGACATGGTTCTGCTCTTCTTTAC
TCTTGTTTGCATTTAGCAGGATTCGATGTAAACCTAGAGGATCTGCAACAATTTCGTCAGCTCCAATCTCGAACTCCCGG
GCATCCAGAATTTAGAGAAACTGATGGTGTAGAAGCCACTACAGGACCTCTAGGACAAGGAGTAGGAAATGCTGTTGGAA
TGGCTCTTTCATTAAAAATGTTAGGAGCCAGATTTAATCAGCCTGCGAATTCTATCTTTGATGCAAAAGTGTATTGCTTA
GCAGGAGATGGGTGCTTCATGGAAGGCGTGAGTCATGAAGCTTGTAGTTTCGCGGGTTCTTTAGGCTTGGATAATCTCGT
TTTGATTTATGATCATAATGAGATTATTTTAGACGGGACTCTTCACGATGTAAGTATTGAGGATACAAAACAGAGATTCT
TAGCATATGGCTGGGATGTGTTTGAAACTGACGGACATGATTTTGAGAGCTTGCATCAGGTTTTCACACAGATCAAGAAA
AGCCAATGCAAACCTACGTTGATTATTGCACATACTATTATTGGACACGGCTCCCCTAAAGAAGGAACCAATAAAGCACA
TGGGTCTCCTTTAGGAGAGGATGGTGTTGCTCAAACTAAAAGTTTCTGGCATCTCCCAGAAGAAAAGTTTTTCGTTCCTT
CGGCAGTGAAGATGTTCTTTGCTGCAAAACAACAGGAAGGTAAGAAATTACAGGAAGAATGGCAAGAACGCTTCCGAGTC
TGGTCTAAACAAGCTCCCGAGCAACATCAAGAATATCTTCGATTGATTCAAGAGATCTCGATTCAAGAACTCGAAGAAAT
TTTGAATCTTATTGATATGCCAGAGTCTATAGCCGGGCGTGCAGCTTCGAATAAAGTCATTCAGGTATTAGCAGAGGATA
TTCCATCCCTCGTAGGGGGATCGGCGGATCTCTCTAGTTCAGATGGTACCTGGATAGCTAAAGAAGGAACTATTAGTGCT
AGCGATTTTCTTGGGCGGAATATTCGCTATGGAGTGCGCGAATTCGGAATGGGCACGATTATGAACGGATTAGCGTATAG
TCAAGTATTCCGTCCTTTTGGGGGAACTTTTTTAGTCTTTTCCGATTATTTGCGTTCCGCGATTCGATTAGCAGCATTAT
CTAAATTGCCGGTAATTTATCAGTTCACTCATGATTCGATTTTTGTTGGAGAGGATGGACCTACACATCAGCCTATAGAG
CAAATCATGTCGCTGCGGGCTATTCCAGGGCTAAGAGTGATTCGTCCTGCGGATGCGAATGAAGTGAAAGGAGCATGGTT
AACTGCTTTAGAAAGCGCTGGTCCAACAGCGTTAATTTTATCTCGACAAAATCTACCTACTCTTAAAGAGACGAAACGTT
CTTTCAGAGAAGGAGTAAGAAAGGGTGCTTATATTCTGGTTAAAGAGGAAGGAGATCGCCCAGACTATACGCTGTGTGCT
TCTGGATCCGAGGTGCATTTGGCTATAGAGGTTGCACAAAGTCTTATGGCTTTAGATAATCGTGTGCGAGTGATTTCATT
CCCTTGTTGGGAGCTATTCGAGAGACAAGACGTTGAGTATCGTGAATCCGTAATAGGAGGAGATTTAGGGTTGCGTGTTT
CTATAGAAGCAGGTACCGCCTTGGGTTGGTACAAATACATCGGTAGCAATGGCTTAGCCATTGCCATAGATGGGTTTGGA
ATGTCCGGAGCTCCCAATGAGGTGGCAGAGACTTGCGGTTTCACTGTAGATAATATTGTGCAGAGAATCCTTTCTGTTTA
G

Protein sequence :
MAGNSDLDIDILEKIAGTIKQLSIESIQKASSGHPGMPLGCAELAAYLYGYVLRYNSKDSRWVNRDRFVLSAGHGSALLY
SCLHLAGFDVNLEDLQQFRQLQSRTPGHPEFRETDGVEATTGPLGQGVGNAVGMALSLKMLGARFNQPANSIFDAKVYCL
AGDGCFMEGVSHEACSFAGSLGLDNLVLIYDHNEIILDGTLHDVSIEDTKQRFLAYGWDVFETDGHDFESLHQVFTQIKK
SQCKPTLIIAHTIIGHGSPKEGTNKAHGSPLGEDGVAQTKSFWHLPEEKFFVPSAVKMFFAAKQQEGKKLQEEWQERFRV
WSKQAPEQHQEYLRLIQEISIQELEEILNLIDMPESIAGRAASNKVIQVLAEDIPSLVGGSADLSSSDGTWIAKEGTISA
SDFLGRNIRYGVREFGMGTIMNGLAYSQVFRPFGGTFLVFSDYLRSAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPIE
QIMSLRAIPGLRVIRPADANEVKGAWLTALESAGPTALILSRQNLPTLKETKRSFREGVRKGAYILVKEEGDRPDYTLCA
SGSEVHLAIEVAQSLMALDNRVRVISFPCWELFERQDVEYRESVIGGDLGLRVSIEAGTALGWYKYIGSNGLAIAIDGFG
MSGAPNEVAETCGFTVDNIVQRILSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 4e-122 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-113 44