Gene Information

Name : pykF (CTA_0360)
Accession : YP_328143.1
Strain : Chlamydia trachomatis A/HAR-13
Genome accession: NC_007429
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 376577 - 378034 bp
Length : 1458 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATCGCTAGAACGAAAATTATTTGTACGATAGGCCCTGCAACGAATACCCCTGAGATGCTGGAAAAGCTTCTTGATGC
AGGGATGAATGTAGCTCGCCTTAATTTTAGCCACGGGACCCATGAAAGCCATGGCCGGACCATCGCTATTCTTAAAGAAC
TACGAGAGAAGCGCCAAGTTCCTTTAGCTATTATGCTAGATACAAAAGGTCCCGAAATTCGTTTAGGCCAAGTAGAATCT
CCTATAAAAGTACAGCCTGGGGATCGTCTTACTCTCGTTAGCAAAGAAATTTTAGGATCCAAAGAAAGCGGCGTTACTCT
TTATCCAAGTTGTGTATTCCCTTATGTTAGAGAACGAACTCCTGTTCTCATTGATGATGGGTATATCCAAGCAGTGGTGG
TCAATGCTCAAGAGCATATGGTGGAAATAGAGTTTCAAAATTCAGGAGAAATAAAATCCAACAAATCTCTTAGCATCAAA
GATATCGATGTTGCTCTTCCTTTCATGACAGAGAAGGATATTGCAGACTTAAAATTTGGGGTAGAACAAGAACTCGATCT
TATCGCTGCTTCGTTCGTCAGATGTAATGAAGATATTGACAGCATGCGTAAAGTTTTGGAAAGCTTTGGTCGTCCTAATA
TGCCCATCATTGCTAAAATAGAAAATCATTTAGGAGTACAAAATTTCCAAGAGATCGCTAGAGCTGCTGATGGTATCATG
ATTGCACGCGGGGATCTTGGTATTGAATTGTCTATTGTTGAAGTTCCTGGACTACAAAAATTTATAGCCCGAGCATCGAG
GGAAACGGGTCGGTTTTGTATCACTGCAACGCAAATGCTCGAGTCAATGATTCGCAACCCCCTTCCTACACGAGCCGAAG
TCTCTGACGTTGCCAACGCCATTTACGATGGAACCTCTGCAGTCATGTTGTCTGGAGAAACTGCCTTAGGAGCCCATCCT
GTACATGCAGTAAAAACAATGCGTTCCATTATCCAAGAGACTGAGAAGACTTTCGATTACCACGCTTTTTTCCAGCTGAA
CGACAAAAACAGCGCTCTCAAAGTTTCTCCTTATCTTGAAGCCATTGGGTTTTCTGGAATCCAAATTGCAGAAAAAGCAT
CTGCCAAAGCCATTATTGTGTATACCCAGACGGGAGGATCTCCGATGTTTTTATCCAAATATCGACCTTATCTCCCTATT
ATTGCTGTTACCCCTAACCGCAATGTGTACTATCGTTTAGCTGTAGAATGGGGAGTATATCCTATGCTAACCCTAGAATC
GAACCATACAGTCTGGCGTCACCAAGCTTGTGTATATGGAGTAGAAAAAGGAATTCTTTCTAACTATGATAAAATTCTTG
TCTTCAGCCGCGGAGCTGGGATGCAAGATACCAACAATCTCACCTTGACAACTGTGCATGATGTGCTATCCCCCTCTCTT
GACGAGATAGTTCCATAA

Protein sequence :
MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPLAIMLDTKGPEIRLGQVES
PIKVQPGDRLTLVSKEILGSKESGVTLYPSCVFPYVRERTPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIK
DIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRPNMPIIAKIENHLGVQNFQEIARAADGIM
IARGDLGIELSIVEVPGLQKFIARASRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIYDGTSAVMLSGETALGAHP
VHAVKTMRSIIQETEKTFDYHAFFQLNDKNSALKVSPYLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPI
IAVTPNRNVYYRLAVEWGVYPMLTLESNHTVWRHQACVYGVEKGILSNYDKILVFSRGAGMQDTNNLTLTTVHDVLSPSL
DEIVP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-62 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-62 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-62 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-62 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_328143.1 pyruvate kinase VFG0479 Protein 6e-63 43