Gene Information

Name : clpC (CTA_0308)
Accession : YP_328094.1
Strain : Chlamydia trachomatis A/HAR-13
Genome accession: NC_007429
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 320221 - 322785 bp
Length : 2565 bp
Strand : +
Note : ClpC/MecB

DNA sequence :
ATGTTTGAGAAGTTTACCAATCGCGCAAAGCAAGTGATTAAGTTGGCGAAAAAAGAGGCTCAACGACTCAATCACAACTA
TCTAGGAACCGAGCACATCTTGTTAGGATTACTAAAATTAGGCCAGGGTGTGGCTGTTAATGTATTACGCACTCTTGGTG
TTGACTTCGATACAGCAAAGCACGAAGTAGAAAGGCTGATTGGCTATGGCCCCGAGATTCAAGTTTACGGAGATCCAGCT
CTTACTGGAAGAGTGAAGAAATCTTTTGAATCCGCTAATGAAGAAGCTGCTCTTTTAGAACACAATTATGTTGGAACTGA
ACATCTTTTGTTAGGTATTCTCAATCAATCCGATGGAGTGGCTTTGCAAGTATTAGAAAATTTGCACGTGGATCCTAAAG
AAATCCGAAAAGAGATTTTAAAAGAATTAGAAACATTTAATTTACAACTCCCCCCCTCTTCCTCCATCACTCCTAGAAAT
ACTAATAGCTCTTCTTCTTCGAAATCTTCTTCTCCTTTAGGAGGTCATACTTTGGGCGGAGATAAACCTGAAAAACTTTC
AGCTTTGAAGGCGTACGGTTACGACTTAACAGAAATGTTTAAAGAATCGCGCCTCGATCCAGTGATCGGGCGTTCTGCAG
AAGTCGAACGATTAATTTTAATTCTTTGTCGTCGAAGAAAAAATAACCCAGTCTTAGTTGGAGAAGCTGGAGTAGGGAAA
ACAGCCATTGTAGAAGGCCTCGCTCAGAAAATTGTCTCAGGAGAAGTTCCTGAAGCTCTTCGTAAAAAACGCTTGATCAC
TTTAGATTTGGCTCTAATGATTGCAGGAACCAAATACAGAGGGCAGTTTGAAGAACGCATCAAAGCTGTGATGGATGAAG
TTCGTAAACATGGGAACATCCTCTTATTTATTGATGAGCTTCACACGATTGTTGGTGCAGGAGCTGCTGAAGGAGCTATC
GATGCTTCTCATATTCTAAAACCAGCTCTAGCTCGAGGAGAAATTCAGTGCATTGGCGCTACGACCCTAGATGAATACCG
TAAACATATAGAAAAAGATGCCGCTTTAGAACGTCGGTTCCAAAAAATCGTTGTTCAACCTCCTAGCGTCGATGAAACAG
TAGAAATTCTCAGAGGTTTAAAGAAAAAATACGAAGAGCATCACAATGTCTTCATCACTGATGAAGCACTAGTTGCTGCA
GCTAAACTCTCTGACCAATATGTTCATGGTCGATTTCTTCCTGATAAAGCAATTGACCTCTTGGATGAAGCTGGAGCTCG
TGTACGAGTCAATACGATGGGACAACCTTCGGACCTGGTGCGTCTAGAAGCTGAGATAGAAAAAACAAAACAAGCTAAAG
AGCAAGCTATCGGAACTCAGGAATACGAAAAAGCTGCTAGCCTTCGTGATGAAGAGAAGAAGTTAAGAGAAAAATTAGGA
AATATGAAACAACAGTGGGAGTCCAATAAGGAAGAACATCAAGTTCCCGTTGATGAAGAAGCTGTTGCACAAGTAGTTTC
CGTACAAACAGGAATTCCTGCAGCTCGTTTAACAGAAGCTGAAAGCGAAAAACTTTTAACCTTAGAAACGACTCTACAAA
AGAAAGTAATCGGCCAAAGTCAAGCTGTTGCTAGTATCTGTAGAGCTATCCGTCGTTCTAGAACAGGCATCAAAGATCCT
AATAGACCTATGGGATCCTTCCTATTTTTGGGCCCAACTGGTGTCGGGAAGACTTTATTAGCGCAGCAAATCGCAATTGA
GATGTTTGGAGGAGAAGATTCTCTTATTCAAGTGGACATGTCTGAGTACATGGAAAAATTTGCAGCCACTAAGATGATGG
GATCTCCTCCAGGATATGTCGGTCATGAGGAAGGGGGTCATCTAACAGAGCAAGTCCGTCGCCGCCCTTACTGTGTTGTG
TTGTTTGATGAAATTGAAAAAGCACATCCAGATATTATGGACCTTATGCTTCAGATTTTGGAGCAAGGGCGTTTAACAGA
CTCATTTGGACGTAAGATCGATTTTCGTAATACCATCATCATTATGACTTCTAACCTAGGAGCAGATTTAATTCGGAAAA
GTGGTGAAATAGGGTTTGGGCTTCGTTCTCACATGGACTATGCAGTTATTAAAGAGAAAATAGATGCTGCAGTTAAGAAG
CATTTAAAACCCGAGTTTATCAACCGTTTAGATGAGAGTGTTATCTTTAAGCCTCTTGAAAAAGAAGCTCTTTCAGAGAT
TATCCATCTAGAAATTAATAAGCTGGGCTCTCGTTTACAAAACTATCAAATGGATCTTAATATTCCTGATTCAGTGATTT
CCTTTTTGGTAACTAAAGGGCATTCGCCAGAAATGGGAGCTCGACCTTTAAGACGTGTTGTGGAGCAGTATCTGGAGGAT
CCTTTGGCAGAAATGCTATTGAAAGAGTCTTGCCGACAAGAAGCTAGAAAATTACGCGCGCGCCTCACAGAAGAACGCGT
TGTTTTCGAAAGAGAAGAAGAAGCTGTTTCTGCTTTAGCTATAGAAGGCGATGGCTCAGAGCCTATTACAGCTGATGAAT
CATAG

Protein sequence :
MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRTLGVDFDTAKHEVERLIGYGPEIQVYGDPA
LTGRVKKSFESANEEAALLEHNYVGTEHLLLGILNQSDGVALQVLENLHVDPKEIRKEILKELETFNLQLPPSSSITPRN
TNSSSSSKSSSPLGGHTLGGDKPEKLSALKAYGYDLTEMFKESRLDPVIGRSAEVERLILILCRRRKNNPVLVGEAGVGK
TAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAI
DASHILKPALARGEIQCIGATTLDEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKKYEEHHNVFITDEALVAA
AKLSDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSDLVRLEAEIEKTKQAKEQAIGTQEYEKAASLRDEEKKLREKLG
NMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESEKLLTLETTLQKKVIGQSQAVASICRAIRRSRTGIKDP
NRPMGSFLFLGPTGVGKTLLAQQIAIEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVV
LFDEIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKSGEIGFGLRSHMDYAVIKEKIDAAVKK
HLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNYQMDLNIPDSVISFLVTKGHSPEMGARPLRRVVEQYLED
PLAEMLLKESCRQEARKLRARLTEERVVFEREEEAVSALAIEGDGSEPITADES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-169 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_328094.1 negative regulator of genetic competence VFG0079 Protein 0.0 51
clpC YP_328094.1 negative regulator of genetic competence VFG0080 Protein 1e-140 50