Gene Information

Name : leuS (CTA_0229)
Accession : YP_328017.1
Strain : Chlamydia trachomatis A/HAR-13
Genome accession: NC_007429
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 238022 - 240481 bp
Length : 2460 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCGCTATGATCCCGGTCTCATAGAAGAAAAATGGCAAAAGTTTTGGAAGAACGAGCAAGTTTTTAAGGCTGAGGAGGA
TGAAACTAAAACAAAATACTATGTTTTAGATATGTTTCCTTATCCATCTGGGGCAGGGTTGCACGTGGGGCATCTAATTG
GCTATACAGCAACAGATATTGTCGCAAGGTATAAGCGAGCCCAGGGGTTTTCAGTTTTACATCCTATGGGTTGGGATAGT
TTTGGGTTGCCTGCAGAGCAGTATGCTATACGCACGGGGACACACCCAAGAGAGACCACAGAGAAAAACATCGCTAATTT
CAAGAAACAGTTAACTGCAATGGGGTTCTCTTACGACGAAAGTCGAGAGTTCGCTACTTCAGATCCAGAATATTATAAAT
GGACTCAAAAGCTTTTTTTAATCCTTTATGAGAAAGGATTAGCCTATATGGCCGATATGGCTGTTAACTATTGTCCTGAG
TTGGGGACTGTTTTATCGAATGAAGAGATTGAAAACGGATTTTCTGTTGATGGGGGGTATCCTGTTGAAAGGAGAATGCT
TCGCCAATGGGTGCTGCGTATTACAGCATTCGCGGATCAGCTCCTAGAAGGACTAGATGAGCTGGATTGGCCAGAAAGTG
TCAAACAATTGCAGAAGAATTGGATTGGGAAGTCTTCAGGAGCTTCTGTTAATTTTGCCACAGAACATGGAGCAATAGAA
GTTTTCACAACAAGACCGGACACTTTGATAGGAGTTTCTTTTTTAGCCTTAGCTCCTGAACATCCCTTGGTCGATCTCCT
CACTTCTGATGAGCAAAAGGCTGTTGTGGCACAGTATATTAAAGAAACACAAAGTAAAAGCGAAAGAGATCGCATCAGCG
AGATGAAAACTAAGAGCGGGGTCTTTACGGGATCTTACGCAAAACATCCTGTCACTCACGAACTTATCCCTATCTGGATC
GCAGATTATGTATTAATCGGCTTTGGTTCAGGAGCTGTCATGGGAGTTCCTGCTCATGACGAACGTGATTTGCTTTTTGC
CGAACAGTTTAATTTACCTGTAGTCTCCGTGCTTAATAAAGAAGGTGTCTGTATTAATAGCTGTTGTGAAGGGTTCCATT
TGGATGGATTGTCCGGAGAAGAAGCTAAGCAATATGTGATTAACTTTTTAGAAGAGAATCATCTTGGAGCAGCAAAAATC
GCTTATAAGTTGCGAGACTGGCTATTCTCGCGTCAACGTTATTGGGGGGAGCCTATACCGATTATCCATTTTGAAGATGG
CTCTTGTCGTCCTTTAAGAGACTATGAACTTCCATTGTTACCTCCGGAAATTCAAGATTATCGACCAGAAGGGGTCGGAC
AAGGACCTTTGGCTAAGGTGCGAGAGTGGGTACAAGTTTTCGACACGGAGACACAACGAGCTGGGAAACGTGAAACACAT
ACCATGCCTCAATGGGCAGGCTCTTGCTGGTACTATTTACGTTTTTGCGATGCCCACAACTCGGCCGCTCCCTGGGCAAA
GGAAAAGGAACAATATTGGATGCCAGTAGATCTGTATATTGGAGGTGCAGAACATGCTGTACTGCACTTACTTTATGCGC
GTTTCTGGCATCAGATTTTCTATGAAGCTGGGATTGTTTCAACACCCGAGCCTTTTAAGAAGCTTGTCAATCAAGGCTTG
GTATTGGCGACATCTTATCGCATTCCTGGGAAAGGATATATATATCCTGAAATAGCAAAAGAAGAAAACGGGAAATGGGT
TGCTCCTTCGGGAGAAGAGTTGGATGTCCGTCAAGAAAAGATGTCGAAATCCAAATTAAATGGGGTGGATCCTCAGATCT
TGATAGATGAATTTGGAGCTGACGCTGTTCGGATGTACGCAATGTTTTCAGGGCCTTTAGATAAAAATAAACTCTGGTCT
AACCAAGGAGTTGCTGGTTGCAGACGATTTTTGAATCGTTTTTATGAAATGGTCTCTTCTGATCGAGTTAAGGAAGATAA
CAATTTTGAAGGCTTATCATTAGCGCATAAGCTTGTGCAGCGAGTAACAGATGCTATTGAAAAATTGTCTTTGAATACGA
TACCGTCCTCTTTTATGGAGTTTATCAATGACTTTGTGAAGCTCGCTGTATATCCGAAGAGTGCTGTAGAAATGGCTGTT
CGGGCTTTGGCTCCAATTGCCCCTCACATTAGTGAAGAGTTGTGGGTGTTGTTAGGCAATTCTCCTGGTGTTCAGAAGTC
CGGATGGCCGAGTGTTTTGCCTGAGTATTTAGAAGGACAGACAGTTACTATTGTAGTTCAGGTAAATGGTAAACTTCGAG
CTCGACTAGATATTATGAAGGATGCTTCTAAAGAAGAAGTCCTAGCGTTAGCAAGGGAATCTGCATCTAAGTACTTAGAG
GGGTGTGAAGTGAAAGAGGCTATTTTTGTTCCTGCTCGATTGGTAAACTTTGTTGTATGA

Protein sequence :
MRYDPGLIEEKWQKFWKNEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVARYKRAQGFSVLHPMGWDS
FGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESREFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPE
LGTVLSNEEIENGFSVDGGYPVERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGAIE
VFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKSGVFTGSYAKHPVTHELIPIWI
ADYVLIGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLNKEGVCINSCCEGFHLDGLSGEEAKQYVINFLEENHLGAAKI
AYKLRDWLFSRQRYWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQRAGKRETH
TMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYARFWHQIFYEAGIVSTPEPFKKLVNQGL
VLATSYRIPGKGYIYPEIAKEENGKWVAPSGEELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWS
NQGVAGCRRFLNRFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVKLAVYPKSAVEMAV
RALAPIAPHISEELWVLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQVNGKLRARLDIMKDASKEEVLALARESASKYLE
GCEVKEAIFVPARLVNFVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 50