Gene Information

Name : EHEC-hlyD (L7050)
Accession : YP_325610.1
Strain :
Genome accession: NC_007414
Putative virulence/resistance : Virulence
Product : hemolysin transport protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1566
EC number : -
Position : 44992 - 46431 bp
Length : 1440 bp
Strand : +
Note : 99 pct identical and equal length to EHEC-hlyD TRSW: Q47463

DNA sequence :
ATGCGCTTTTACATGAAAGGTTTATGGGATTTGGTTTGCCGTTATAAGACGGTTTTTTCTGATGTCTGGAAAATTCGTCA
CACACTTGATGCTCCTGTGAGAGAAAAAGATGAGTATGCATTTCTTCCTGCTCACCTTGAACTCATTGAAACACCAGTAT
CCAGACGTTCTCATTTTGTTGTATGGAGTATTTTATTATTTGTAATTATATCTCTTCTCTTATCTGTTCTTGGGAAAGTT
GAAGTGGTTTCAGTAGCAAATGGTAAGTTTACTCATAGTGGAAGAAGCAAAGAAATAAAACCGATAGAGAATGCGATTGT
AGAAAAAATAATGGTAAAAGATGGCTCTTTTGTAAAAAAAAATGATCCATTAGTTGAATTGACGGTGCCTGGTGTTGAAT
CTGATATTTTAAAATCAGAAGCATCTTTGTTGTATGAAAAAACAGAACAATATCGCTACGCAATTCTTTCTGAATCAATA
CAACGGAATGAGCTTCCTGAAATAAGGATAACAGATTTTCCTGGCGGAGAAGATAATGCGGGAGGTGAACATTTTCAGAG
GGTTAGCTCATTAATAAAAGAGCAATTCATGACATGGCAGAACAGAAAAAATCAAAAGCAGCTCACATTAAATAAAAAAA
TAGTTGAACGGGATGCAGCGCTTGCTCGTGTTAGCCTGTATGAGCATCAGGTATCACAGGAAGGAAGAAAACTCAATGAT
TTTAAGTATTTGTTGAATAAAAAAGCTGTTTCTCAACATTCAGTTATGGAGCAGGAAAATAGCTATATTCAGGCAAAAAA
TGAACATGCAGTCTGGCTTGCACAGGTTTCTCAACTTGAAAAAGAAATAGAACTTGTGCGGGAAGAACTGGCACTGGAGA
CGAATATCTTCAGAAGTGAAATTATCGAGAAGCACAGAAAATCAACAGATAACATTGTGTTGCTGGAGCATGAGCTTGAA
AAAAACAGGCAGAGAAAAGCATCATCTTTTATTAAAGCTCCTGTGAGTGGTACTGTTCAGGAGTTAAATATACATACAGA
AGGTGGTGTTGTCACAACAGCAGAAACGCTGATGATTATTGTCCCTGATAATGATATTCTCGAAGTAACAGCATCTGTAC
TTAACAAGGATATCGGTTTTATACAACCTGGACAGGAGGTCGTTATTAAAGTAGATGCATATCCATATACACGTCATGGT
TACCTTACAGGGAAAGTAAAAAATATAACTGCAGATTCTGTTTCTGTTCCGGATACAGGGCTTGTATTTAACGTGATTAT
ATCTGTTGATCGGAATGATATACAGGGAGAAAGAAAAAAAATCCCTGTTACAGCTGGAATGACTGTTATGGCAGAAATAA
AAACCGGGGTGCGTAGTGTTATCAGCTATCTTCTTAGTCCATTAAAGGAAACTATTAATGAAAGTTTACGTGAACGTTAG

Protein sequence :
MRFYMKGLWDLVCRYKTVFSDVWKIRHTLDAPVREKDEYAFLPAHLELIETPVSRRSHFVVWSILLFVIISLLLSVLGKV
EVVSVANGKFTHSGRSKEIKPIENAIVEKIMVKDGSFVKKNDPLVELTVPGVESDILKSEASLLYEKTEQYRYAILSESI
QRNELPEIRITDFPGGEDNAGGEHFQRVSSLIKEQFMTWQNRKNQKQLTLNKKIVERDAALARVSLYEHQVSQEGRKLND
FKYLLNKKAVSQHSVMEQENSYIQAKNEHAVWLAQVSQLEKEIELVREELALETNIFRSEIIEKHRKSTDNIVLLEHELE
KNRQRKASSFIKAPVSGTVQELNIHTEGGVVTTAETLMIIVPDNDILEVTASVLNKDIGFIQPGQEVVIKVDAYPYTRHG
YLTGKVKNITADSVSVPDTGLVFNVIISVDRNDIQGERKKIPVTAGMTVMAEIKTGVRSVISYLLSPLKETINESLRER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 5e-109 58
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 1e-117 57
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 2e-117 57
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 1e-117 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EHEC-hlyD YP_325610.1 hemolysin transport protein VFG0843 Protein 0.0 100
EHEC-hlyD YP_325610.1 hemolysin transport protein VFG1556 Protein 8e-118 57
EHEC-hlyD YP_325610.1 hemolysin transport protein VFG1502 Protein 1e-117 57
EHEC-hlyD YP_325610.1 hemolysin transport protein VFG0908 Protein 4e-118 57