Gene Information

Name : leuS (Ava_4936)
Accession : YP_325428.1
Strain : Anabaena variabilis ATCC 29413
Genome accession: NC_007413
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 6205668 - 6208286 bp
Length : 2619 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGACTCCCGATACAACCCCGCAATACTTGAGGAAAAATGGCAAAAAACATGGGTAGAACTTGGTTTAGATAAGACCCA
AACACAAAGCAATAAACCAAAATTCTACGCTCTATCCATGTTTCCCTATCCATCGGGCAGCCTACACATGGGTCACGTCC
GTAATTACACAATTACAGATGTGATTGCCCGCCTCAAACGAATGCAAGGGTATCGGGTACTGCATCCAATGGGATGGGAT
GCCTTTGGCTTACCAGCAGAAAACGCCGCCATTGACCGTGGTGTACCTCCTGCCAACTGGACTTATCAAAACATTACCCA
AATGCGGCAACAATTGCAGCGTCTTGGTTTATCTATTGACTGGGATAGCGAAGTTGCCACCTGTTCGCCAGACTATTACA
AATGGACACAGTGGATTTTCTTACAGTTCTTGCAAGCGGGGTTAGCTTACCAAAAAGAAGCAGCCGTCAACTGGGACCCC
ATTGACCAAACCGTATTGGCAAACGAGCAGGTTGATAACGAAGGTCGTTCTTGGCGCAGTGGCGCGATCGTTGAGCGTAA
ATTGCTCAGGCAGTGGTTTTTAAAGATTACCGACTACGCTGAAGAATTATTAAACGACTTAGATAAATTGACCGGTTGGC
CAGAACGCGTCAAATTGATGCAGGCGAACTGGATAGGGAAATCTGTAGGCGCATATTTAGAATTTCCCATTGTCGGCAGC
ACTGAGAAAATTGCTGTGTATACCACCCGGCCTGATACAGTTTACGGTGTTAGCTATGTAGTATTGGCACCAGAACACCC
CCTCACCAAACAAGTCACCAGCAAAACTCAACAAGCAGTAGTAGACACCTTTATTCAAGAGGTGACAAATCAAAGCGAGT
TGGAACGTACCGCCGAAGATAAACCTAAACGCGGTGTAGCAACCGGCGGTAAGGCAATCAACCCGTTTACAGGGGAAGAA
GTACCCATTTGGATTGCCGACTATGTACTGTACGAGTATGGTACTGGGGCTGTGATGGGTGTACCTGCCCATGATGTACG
GGATTTTAAATTTGCTCAGAGATATGATTTACCCATTGATTTTGTCATTGCAGCCCCTGATGATGTAGCAGGTTTTGACT
TAAGCCCGACATCAGAGACAGAAGAAGTCACACAAGTCGTGCAAATAGAATATAACCAAGCATACACAGAGCCAGGAATC
TTAATTAATTCCGGGGCTTTTACTGGTATGACTTCCACAGATGCCAAGCAAGCGATTGTGAAATATGCCACAGAAAAAGG
TTTTGGCAAAGAACGTATTCAATATCGCTTGCGGGACTGGTTGATTTCTCGGCAACGTTATTGGGGCGCACCAATTCCTG
TAATTCATTGTCCCAACTGTGGGATAGTACCAGTGCCAGACAAAGATTTGCCAGTTATCTTACCAGAAGAAGTGGAATTT
ACTGGACGTGGTGGTTCACCGTTGGCACAGTTGGAAAGCTGGGTAAATGTGCCTTGTCCTACCTGTGGTAGTCCTGCCAA
ACGGGAAACTGACACGATGGATACCTTTATTGATTCCTCGTGGTATTTCTTGCGGTTTACTGATGCTAGGAACGAAGCAC
AGGTATTTGAATCAGCAAAAACCAATGACTGGATGCCCGTAGACCAATATGTAGGCGGTATTGAACACGCGATTTTACAC
TTATTGTATTCCCGGTTTTTTACTAAAGTGCTGCGCGATCGCGGCTTGTTGAACTTTGATGAACCTTTTGAACGTTTGTT
AACTCAAGGGATGGTACAAGGTTTAACTTACTTCAATCCGAACAAGGGGGGGAAAGATAAGTGGGTTCCTTCCCATTTAG
TTAACCCCAATGACCCTCGTGACCCCCAAACAGGTGAACCATTGCAACGGCTTTATGCCACCATGTCCAAATCTAAAGGC
AACGGTGTCGCACCAGAAGATGTGATTGCTAAATATGGTGTAGACACAGCACGGATGTTCATCTTATTTAAAGCGCCGCC
AGAAAAAGATTTGGAATGGGATGAAGCTGATGTAGAAGGACAATTCCGCTTTTTAAATCGGGTTTGGCGTTTGGTGACAG
ATTATGTTGCATCTGGGGTCAACCCTAAAAATAAATCTGGTGAATTGAGCAAGTCAGAAAAAGATTTACGGCGGGCAATT
CACAGTGCAATTCAGTCGGTGACAGAAGATTTAGAGGATGAGTATCAGTTTAATACTGCTATTTCTGAGTTGATGAAGTT
AAGCAATGCCCTTACTGATGCTAACGGCAAAGATTCACGGGTCTATGCTGAAGGTATCCACACATTAGTGGTGTTGCTGG
CTCCCTTTGCGCCACATATTGCTGAAGAATTGTGGCAACTATTGGGTAATAGCGAATCAGTGCATACGCAAACCTGGCCT
GCTTTTGACCCAGCCGCTTTAGTTGCCGATGAAATCACTTTGGTGATTCAAGTGAATGGTAAGAAGCGTGCTGATATTCA
AGTTCCGTCACAAGCTGATAAAGCTGAGTTGGAGAAATACGCCCGCGAATCAGAAGTTGTGCAGCGTCACCTGGAAGGTA
AGGAAATTAAAAAGGTAATTGTCGTACCTGGAAAGTTAGTTAATTTTGTCGTTGGTTAA

Protein sequence :
MDSRYNPAILEEKWQKTWVELGLDKTQTQSNKPKFYALSMFPYPSGSLHMGHVRNYTITDVIARLKRMQGYRVLHPMGWD
AFGLPAENAAIDRGVPPANWTYQNITQMRQQLQRLGLSIDWDSEVATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDP
IDQTVLANEQVDNEGRSWRSGAIVERKLLRQWFLKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSVGAYLEFPIVGS
TEKIAVYTTRPDTVYGVSYVVLAPEHPLTKQVTSKTQQAVVDTFIQEVTNQSELERTAEDKPKRGVATGGKAINPFTGEE
VPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAQRYDLPIDFVIAAPDDVAGFDLSPTSETEEVTQVVQIEYNQAYTEPGI
LINSGAFTGMTSTDAKQAIVKYATEKGFGKERIQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVILPEEVEF
TGRGGSPLAQLESWVNVPCPTCGSPAKRETDTMDTFIDSSWYFLRFTDARNEAQVFESAKTNDWMPVDQYVGGIEHAILH
LLYSRFFTKVLRDRGLLNFDEPFERLLTQGMVQGLTYFNPNKGGKDKWVPSHLVNPNDPRDPQTGEPLQRLYATMSKSKG
NGVAPEDVIAKYGVDTARMFILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYVASGVNPKNKSGELSKSEKDLRRAI
HSAIQSVTEDLEDEYQFNTAISELMKLSNALTDANGKDSRVYAEGIHTLVVLLAPFAPHIAEELWQLLGNSESVHTQTWP
AFDPAALVADEITLVIQVNGKKRADIQVPSQADKAELEKYARESEVVQRHLEGKEIKKVIVVPGKLVNFVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-172 44