Gene Information

Name : hemC (Ava_4774)
Accession : YP_325266.1
Strain : Anabaena variabilis ATCC 29413
Genome accession: NC_007413
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 6001201 - 6002211 bp
Length : 1011 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAGAGTGAAATTATCGCCTGGTTTGACATATTGTTTTATGACTTCAGTTGTTTCCAGTGCTAGACGCACAATCCGTAT
AGGTTCTCGTAAAAGTCAACTCGCTCTAGTTCAGACATACTGGGTTAGAGAGCAATTACAAAACAGTTTCCCTGATATCA
ATTTTGAAGTCCACACCATGTCTACCCAAGGCGACAAAATCCTTGATGTAGCACTAGCCAAAATCGGTGATAAAGGACTA
TTCACCAAAGAACTAGAAGTGGGGATGATCAATGAGGAGATTGATTTTGCTGTTCATTCCCTCAAAGATTTGCCGACTAA
CTTACCAGAAGGGTTAGCACTAGCCGCCATTACAGAACGGGAAAACCCCGCCGATGCACTAGTAGTGCATGAAAATTTTA
AGGATAAGCAAATTGATACCTTACCAGCAGGCGCGGTAATTGGGACATCTTCTTTGCGACGCTTGGCGCAGTTACGCAAC
CAATTTCCCCACTTGACATTTAAAGATGTACGGGGAAATTTGAATACACGGTTAGCTAAACTTGATGCAGGCGAGTATGA
CGGTCTAATTTTAGCGGCTGCTGGGTTACAACGCTTAGGTATGGGCGATCGCATCCACCAAGTCCTCCCCAAAGAAGTTT
CGCTCCACGCCGTTGGTCAAGGCGCTCTAGGGATTGAATGCCGTGCTAATGATGCGGAATTAATCACTATACTCAAAGCC
ATTGAACACCCCCAAACACGCGATCGCTGTCTTGCTGAACGCTCCTTTTTACGCAGTTTAGAGGGCGGTTGTCAAGTACC
CATCGGTGTAAATACAGAAATCAATGGTGATGAATTAATCCTCACAGGTGTGGTTGCCAGTGTAGACGGTCAAAACTTAG
TGAAAGACACCGTTTCGGGTGATGCTAGTGATGCCGAAGCGATCGGTATAAGATTAGCCGAACTCCTCCGGGAACAAGGA
GCGCAAGAGATTTTAAATACAATCTTTGCAGAGATCCAACGTGGTTCTTAA

Protein sequence : 
MRVKLSPGLTYCFMTSVVSSARRTIRIGSRKSQLALVQTYWVREQLQNSFPDINFEVHTMSTQGDKILDVALAKIGDKGL
FTKELEVGMINEEIDFAVHSLKDLPTNLPEGLALAAITERENPADALVVHENFKDKQIDTLPAGAVIGTSSLRRLAQLRN
QFPHLTFKDVRGNLNTRLAKLDAGEYDGLILAAAGLQRLGMGDRIHQVLPKEVSLHAVGQGALGIECRANDAELITILKA
IEHPQTRDRCLAERSFLRSLEGGCQVPIGVNTEINGDELILTGVVASVDGQNLVKDTVSGDASDAEAIGIRLAELLREQG
AQEILNTIFAEIQRGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-64 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-64 50