Gene Information

Name : Ava_1125 (Ava_1125)
Accession : YP_321644.1
Strain : Anabaena variabilis ATCC 29413
Genome accession: NC_007413
Putative virulence/resistance : Resistance
Product : Cd/Co/Hg/Pb/Zn-translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.3
Position : 1373914 - 1376169 bp
Length : 2256 bp
Strand : -
Note : -

DNA sequence :
ATGACTCAAACTCCTGAATTGAAAACCGAGATTCTGCAAGTGAGTGGTATGGACTGTGGTAGTTGTGCCAAGACCATTGA
AGTTGGTTTGCAACAATTAAGCGGTGTCACGGAAGCATCAGTGAGTTTTGCCACTGGTAAAGTCAGGGTGTCTTACAACC
AAGAGCATTTGAGTCAGAAGACGATCTGCGATCGCATTCAAGCTTTAGGTTATACAGTAGAACAGAGTTCTCAGGTAGAG
TCAGAGCAGAAAACTCATACCTGTGACCATGACCATGATCATCACAATCATCATCATTCCCTAGCCCATGACCATCAGCT
TGTGCAGGTAGCTGAGGCTAAAATCCCTGGTATGAATTGTGGTACTGATTCCACAAACTGGAAATTCTGGCTGACTAACC
GCCGGGGACAGAGTGTGATTTTGACAGGTATAGGGTTAGGGTTGGGCTTACTGGCACAATATTTAGGATTACCCATTTGG
ATAGCACGGGCTTTTTATAGTGTTGGTATAGTCATTGCCGGTTATCCCATTGCCAAGGCTGGTTTATTTGAGTTGCGCTT
GCGTCGCGCCGATATGAATCTGCTGATGACGATTTCTGTGATTGGCGCAGTAATTTTGGGAGACTGGTTTGAAGCCGCCT
TAGTCTTGTTTTTGTTCTCCTTTGGGACGACACTGCAAATTTTTACCTTTGGTCGCACCCGCCACGCCATCAGCGCCTTG
ATGGATTTGACACCACCTACAGCTACCGTTAGGCGGGGGAATCAGGAAGTTACAGTTCCCGTGGAAAGTGTGCAAGTTGG
AGAAATTTTGACAATTCGCCCCGGAGGGCGTATAGCCTTGGATGGCGTAGTTGTTTCTGGTGCAAGTACCATTGACCAAT
CATCAATTACAGGCGAGTCCATCCCCGAAGATAAACAAAAAGGTGATACCGTCTTTGCGGGAACGGTGAATCAGTCGGGC
TTTTTGGAAGTCAAGGTTACCCACACGGCTAATGATACCACTGTGGCTAAAATTATCCATTTAGTAGAACAAGCCCAAGA
AAGCCGCGCACCTTCTCAGCAGTGGGTAGATCGGTTTGCAGAAAGATACACACCCATTGTCATTTTCATGGCGATCGCCA
TTGCTGTAATTCCCCCCTTAGCCTTTGCTCAACCTGGGGACGTTTGGTTTTATCGAGCGCTGGTCATGCTTGTAATTGCT
TGTCCCTGTGCCTTAGTGATTTCTACCCCAGTTTCCATCGTCAGCGCCATCGGTGCAGCAACTCGTCAAGGTGTGTTATT
TAAGGGCGGTAATGCACTAGAGACAGCCGGACGTTTGACTACCCTGGCTTTTGATAAGACAGGTACGATTACTCAAGGGT
TACCTGTTGTACAGCAGATTTATAATTTTGGGGCGGCGAATGCAAACATGGTGTTACAAATTGCCGCTTCCCTAGAACAA
CACTCTGAACATCCACTAGCCAAGGCGATTGTCACCAAGGCTGATGAATTGGGTATGGAATTGGCAATACCGATTAAATT
CACCGCCTTACCAGGTAAAGGGATTCAAGCAAATCTAGGTAAAATATTATACTTAGTTGGTAATCGTCGGCTGTTTTCCG
AGCAAGATATTCCCTTATCTGGTGAAGCCGAGTCTCTGCTGACAAAAATCGAACAACAGGGGCAAATTCCCGTACTGGTA
GGGACGAAACAAGAATTATTAGGAGCGATCGCCCTCTCAGATGGTATCCGCTTAGAAGCCACAGAAGCCTTACGACAGTT
GAAGCGCATGGGATTAAACAGGTTAGTGATGTTAAGTGGCGATCGCACTCCCGTTGCCCAGCAAATTGCCCAACAAGTAG
GTATTACAGAATACAGAGCAGAACTATTACCACAAGATAAACTCCAAGAAATTCAACAGTTGCGTCAAACAGGGGTGGTA
GGTATGGTTGGGGATGGGATTAACGACACTCCGGCGCTGGCGGCGGCGGATATCAGTTTTGCCGTTGGGGGAATAGATAT
TGCCCTAGAGACAGCCGATGTAGTCATCGTGGGCAGTGACCTCAGACGACTTGCCTATGCAGTAGACTTAAGCCGTCGCA
CGGTATCAGTGATTCAGCAGAATGTCATATTTTCCCTAGTCACAAAAGCTTTGTTTTTACTGTTAGGAACCTTTGGATTT
GTGGGGTTAGCTGTAGCAGTTTTAGCTGATACAGGAACTTCCTTATTAGTGACTGCAAATGGAATGCGGTTATTCACAAC
GAAAAAAATAATTTAA

Protein sequence :
MTQTPELKTEILQVSGMDCGSCAKTIEVGLQQLSGVTEASVSFATGKVRVSYNQEHLSQKTICDRIQALGYTVEQSSQVE
SEQKTHTCDHDHDHHNHHHSLAHDHQLVQVAEAKIPGMNCGTDSTNWKFWLTNRRGQSVILTGIGLGLGLLAQYLGLPIW
IARAFYSVGIVIAGYPIAKAGLFELRLRRADMNLLMTISVIGAVILGDWFEAALVLFLFSFGTTLQIFTFGRTRHAISAL
MDLTPPTATVRRGNQEVTVPVESVQVGEILTIRPGGRIALDGVVVSGASTIDQSSITGESIPEDKQKGDTVFAGTVNQSG
FLEVKVTHTANDTTVAKIIHLVEQAQESRAPSQQWVDRFAERYTPIVIFMAIAIAVIPPLAFAQPGDVWFYRALVMLVIA
CPCALVISTPVSIVSAIGAATRQGVLFKGGNALETAGRLTTLAFDKTGTITQGLPVVQQIYNFGAANANMVLQIAASLEQ
HSEHPLAKAIVTKADELGMELAIPIKFTALPGKGIQANLGKILYLVGNRRLFSEQDIPLSGEAESLLTKIEQQGQIPVLV
GTKQELLGAIALSDGIRLEATEALRQLKRMGLNRLVMLSGDRTPVAQQIAQQVGITEYRAELLPQDKLQEIQQLRQTGVV
GMVGDGINDTPALAAADISFAVGGIDIALETADVVIVGSDLRRLAYAVDLSRRTVSVIQQNVIFSLVTKALFLLLGTFGF
VGLAVAVLADTGTSLLVTANGMRLFTTKKII

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 5e-116 44
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 5e-116 44
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-114 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ava_1125 YP_321644.1 Cd/Co/Hg/Pb/Zn-translocating P-type ATPase BAC0298 Protein 4e-102 47
Ava_1125 YP_321644.1 Cd/Co/Hg/Pb/Zn-translocating P-type ATPase BAC0100 Protein 3e-62 41