Gene Information

Name : guaA (Ava_1054)
Accession : YP_321573.1
Strain : Anabaena variabilis ATCC 29413
Genome accession: NC_007413
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1283341 - 1284963 bp
Length : 1623 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAATACAGCGGTGACTCTACTAACCGAACAAGCCCCTCAACCAATAGAAGAGTTTGGGCAGCTTGAGCGTCAAATCAT
TATCATATTAGACTTCGGCTCTCAGTATTCAGAACTGATTGCCCGGCGCATCCGCGAGACTCAAGTATACTCTGAAGTTT
TGTCTTATCGCACCTCTGCTGAACATTTACGCCAACTAAATCCCAAGGGCATCATTCTTTCTGGTGGTCCCAGTTCAGTT
TATAGCGATCGCGCTCCCCATTGTGACCCAGAAATTTGGAATTTGGGAGTTCCCATTTTGGGTGTCTGCTACGGAATGCA
GCTGATGGTCAACCAACTCGGCGGCGAAGTAGCCAAAGCTGACCGGGGTGAGTATGGCAAAGCATCATTACATATTGATG
ATCCCACCGACCTACTGACCAACGTTGAAGATGGCACAACGATGTGGATGAGTCATGGTGATTCAGTCACAAAAATGCCC
CCAGGGTTTGAAGTGCTGGCACATACAGATAATACTCCCTGTGCTGCTGTTGCTGACCACGACAAAAAGCTTTATGGCGT
GCAGTTCCATCCAGAAGTAGTCCATTCCATCGGTGGTTTGGCATTAATCCGCAACTTTGTGTATCACATCTGCGAGTGTG
AACCCACCTGGACAACAGCCGCTTTTGTGGAAGAAGCTATTCGGGAAGTTCGGGCTAAAGTTGGTGACAAGCGAGTACTA
TTGGCGCTTTCGGGAGGAGTCGATTCTTCTACACTGGCTTTCTTGATGCACAAAGCCATCGGCGACCAATTGACCTGTGT
ATTTATAGACCAAGGCTTTATGCGGAAGTATGAGCCAGAAAGGTTGGTGAAACTATTTCAAGAGCAGTTTCACATCCCTG
TTGAATATGTTAACGCCCGCGATCGCTTCTTAGATATCATGGTTGGCGTGACAGACCCAGAAGAAAAACGTCGTCGCATT
GGACATGAATTCATCCAGGTATTTGAAGAAACATCGAGAAATTTGGGACCCTTTGACTATCTAGCACAAGGGACTCTTTA
CCCAGATGTCATTGAATCAGCTGATACCAATGTTGACCCCCAAACCGGGGAACGGGTAGCAGTAAAAATCAAAAGCCATC
ACAACGTTGGTGGATTACCCAAAGACTTGAGATTTAAACTGGTTGAACCCCTGCGGAAACTATTTAAAGATGAAGTCCGT
AAAGTAGGGCGGTCTGTTGGCTTACCAGAAGAGATTGTCCAACGCCAGCCATTTCCTGGCCCTGGTTTAGCTATTCGGAT
TTTAGGTGAAGTCACCGCCGACAGATTGAACATTCTGCGCGATGCTGATTTGATTGTGCGCCAAGAAATTAACCAACGTG
GTTTATACAACGAATATTGGCAAGCATTCGCCGTCTTACTACCTATCCGTAGTGTGGGCGTAATGGGTGATCAACGCACC
TATGCTTATCCTATAGTCTTACGCATTGTTAAAAGCGAAGATGGCATGACAGCAGATTGGGCGCGTGTACCTTACGATGT
TTTAGAAGCAATTTCTAACCGCATTGTCAACGAGGTTAAAGGCGTTAATCGCGTAGTGTTTGATATTACCTCCAAGCCAC
CCGGAACCATCGAGTGGGAATAA

Protein sequence :
MNTAVTLLTEQAPQPIEEFGQLERQIIIILDFGSQYSELIARRIRETQVYSEVLSYRTSAEHLRQLNPKGIILSGGPSSV
YSDRAPHCDPEIWNLGVPILGVCYGMQLMVNQLGGEVAKADRGEYGKASLHIDDPTDLLTNVEDGTTMWMSHGDSVTKMP
PGFEVLAHTDNTPCAAVADHDKKLYGVQFHPEVVHSIGGLALIRNFVYHICECEPTWTTAAFVEEAIREVRAKVGDKRVL
LALSGGVDSSTLAFLMHKAIGDQLTCVFIDQGFMRKYEPERLVKLFQEQFHIPVEYVNARDRFLDIMVGVTDPEEKRRRI
GHEFIQVFEETSRNLGPFDYLAQGTLYPDVIESADTNVDPQTGERVAVKIKSHHNVGGLPKDLRFKLVEPLRKLFKDEVR
KVGRSVGLPEEIVQRQPFPGPGLAIRILGEVTADRLNILRDADLIVRQEINQRGLYNEYWQAFAVLLPIRSVGVMGDQRT
YAYPIVLRIVKSEDGMTADWARVPYDVLEAISNRIVNEVKGVNRVVFDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-139 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-139 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-139 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-130 53