Gene Information

Name : Nwi_2468 (Nwi_2468)
Accession : YP_319073.1
Strain : Nitrobacter winogradskyi Nb-255
Genome accession: NC_007406
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2690618 - 2692558 bp
Length : 1941 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACATTCGCTCCAATCCGGACACCACGCGCCCCGCCGTCACCACCGGTGCCCTGCCCTCGTCCCGCAAGATGTTCTC
CGCGCCCGACGCCGCGCCCGATCTGCGGGTGCCGCTGCGTGAGATCCTCCTGTCCGAGGGCGCGGGCGAGCCGAACCTGC
CGGTCTATGACACCTCCGGTCCGTATACCGATCCGAACGTCATCATTGATGTGAATGCCGGGCTGCCGCGCACGCGTCTC
GCCTGGGTGAAGGAACGCGGCGGCGTCGAGGAATATGACGGCCGAGAGATCAAGCCGGAGGACAACGGCAATGTCGGCGC
AAGCCACGCCGCGGCGGCGTTCAAGGCGCACCACAAGCCGCTGAGGGGCATCGGCGATGCGCCGATCACACAGCTGGAGT
TCGCCCGCGCCGGCATCATCACCAAGGAAATGATCTATGTGGCCGAGCGCGAGAATCTCGGACGCAAGAAGCAACTCGAA
CGCGCCGAAGCCGCGCTGGCCGACGGTGAAGCCTTCGGCGCCTCCGTACCCGCCTTCATCACGCCGGAATTCGTGCGCGA
GGAGATCGCGCGCGGCCGTGCCATCATTCCTTCCAACATAAACCACGCCGAACTGGAGCCGATGATCATCGGCCGCAATT
TCCTGGTGAAGATCAACGCCAATATCGGCAACTCGGCCGTGACCTCCTCGGTTGAAGAAGAGGTGGACAAGATGGTGTGG
GCGATCCGCTGGGGCGCCGACACGGTGATGGACCTCTCGACCGGCCGCAACATTCACACCACGCGCGAATGGATTTTGCG
CAACTCGCCCGTTCCGATCGGAACGGTGCCGATCTATCAGGCGCTGGAGAAATGCGACGGCGACCCGGTGAAACTGACGT
GGGAGCTTTATCGCGACACGCTGGTGGAGCAGTGCGAACAGGGCGTCGATTACTTCACCATCCATGCCGGCGTACGGCTG
CCCTACATCCACCTCACCGCCGACCGCGTCACCGGCATCGTCTCGCGCGGCGGCTCGATCATGGCGAAGTGGTGCCTCGC
CCACCACAAGGAGAGCTTCCTCTATACGCACTTCGAGGAAATCTGCGACCTCATGCGCAAGTATGACGTGTCGTTCTCGC
TCGGTGACGGCCTGCGCCCCGGCTCGATCGCGGACGCCAACGACCGCGCGCAGTTCGCCGAACTGGAAACGCTCGGCGAA
CTCACGCAGATCGCATGGAAGAAGGGCTGCCAGGTGATGATCGAAGGCCCCGGCCACGTGCCGATGCACAAGATCAAGAT
CAACATGGACAAGCAGCTGAAAGAATGCGGCGAAGCGCCGTTCTATACGCTAGGGCCGCTGACCACCGACATCGCGCCTG
GCTATGACCACATCACCTCGGGCATCGGCGCCGCCATGATCGGCTGGTTCGGCTGCGCGATGCTCTGCTACGTGACGCCG
AAGGAGCATCTCGGCCTGCCCAACCGCGACGACGTGAAGACCGGCGTGATTACCTACAAGATCGCGGCGCACGCCGCCGA
CCTCGCCAAGGGCCATCCGGCCGCGCAACTGCGCGATGACGCATTGAGCCGCGCGCGGTTCGACTTCCGCTGGCAGGACC
AATTCAACCTCGGTCTCGATCCTGACACCGCGGTCGCCTTCCACGACGAGACGCTGCCGAAGGACGCGCATAAGGTCGCG
CACTTCTGTTCGATGTGCGGACCGAAATTCTGCTCGATGAAGATCACGCAGGATGTGCGCGACTACGCTGCGACGCTCGG
CGATAACGAGAAGGCCGCGCTCTATCCGGACACCGCACCAAAGGCGAATGACGCCGCAGGCGTCCCCGAGCCGTCTTATC
GCGACCAGGGCATGAAAGAGATGAGCGCGAGGTTCAAGGAGATGGGAGGTAACGTGTATCTAGATGCCGAGAAGGTGAAG
GAGAGTAATCGGGTGTTGTGA

Protein sequence :
MNIRSNPDTTRPAVTTGALPSSRKMFSAPDAAPDLRVPLREILLSEGAGEPNLPVYDTSGPYTDPNVIIDVNAGLPRTRL
AWVKERGGVEEYDGREIKPEDNGNVGASHAAAAFKAHHKPLRGIGDAPITQLEFARAGIITKEMIYVAERENLGRKKQLE
RAEAALADGEAFGASVPAFITPEFVREEIARGRAIIPSNINHAELEPMIIGRNFLVKINANIGNSAVTSSVEEEVDKMVW
AIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCDGDPVKLTWELYRDTLVEQCEQGVDYFTIHAGVRL
PYIHLTADRVTGIVSRGGSIMAKWCLAHHKESFLYTHFEEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGE
LTQIAWKKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTP
KEHLGLPNRDDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFDFRWQDQFNLGLDPDTAVAFHDETLPKDAHKVA
HFCSMCGPKFCSMKITQDVRDYAATLGDNEKAALYPDTAPKANDAAGVPEPSYRDQGMKEMSARFKEMGGNVYLDAEKVK
ESNRVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 65
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 64
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 64