Gene Information

Name : Nwi_2233 (Nwi_2233)
Accession : YP_318839.1
Strain : Nitrobacter winogradskyi Nb-255
Genome accession: NC_007406
Putative virulence/resistance : Resistance
Product : dihydropteroate synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0294
EC number : 2.5.1.15
Position : 2428648 - 2429526 bp
Length : 879 bp
Strand : +
Note : -

DNA sequence : 
ATGACCTCGGCGGATTCCATGTCCAGAGCTGTGACGGATGATGCACGTCATCCCGCGCTTGAGGCGCTGCTGTCGCGCCC
CTGCCCGGCGGTCATGGGGATCCTGAACATCACCCCCGACTCGTTCTCCGATGGCGGTCAGTTCATGACGCCCGACCGGG
CCGTGGCGCAGGCGCGCCGCATGATCGCGGACGGGGCCGACATCATCGATATCGGCGCGGAGTCAACCCGCCCCTACGGA
GCGCAGCCGATCTCGCGCGACGAGGAAATGCGGCGGCTGGAGCCGGTGCTCGCCGCGGTGGTCGCGCTTGGAATTTCCGT
CTCCATCGACAGCATGAAGTCCCCGGTGGTGGAGTGGGCGCTCGGGAACGCGGCCGCGATCGCCAACGACGTGTGGGGAT
TGCAGCGCGATCCCGACATGGCCCGCGTCGTCGCCGCGCGCAACGCGCCCGTCGTCGTCATGCATAACCGGGACAAGCCC
GATGGTACGCTCGACATCATGCGGGACATCACAGCGTTCTTCGAACGATCGCTGAAGATCGCGGCGCAAGCCGGCATACC
CGCCAGCCGCATCATCCTTGATCCCGGTATCGGATTCGGCAAGACGCCGGAACAGAGCATGATCGCGCTGGCCCGGCTCG
GCGAATTGCAGACCTTCGGATTGCCGGTTCTCGTGGGCGCGTCCCGCAAGCGCTTCATCAGCATGGTGACGCCATCAGAG
CCGCAACAACGGCTCGGCGGCTCGCTCGCCGCGCATCTGATCGCGGCAAGAAGCGGCGCGCGCATCATCCGCACACACGA
TGTGGCCGAGACGGTGCAGGCGCTGCGGGTGGCGCACGCCATCGAGACCGCAACACAGCCGGGATCTTTTGAACCATGA

Protein sequence : 
MTSADSMSRAVTDDARHPALEALLSRPCPAVMGILNITPDSFSDGGQFMTPDRAVAQARRMIADGADIIDIGAESTRPYG
AQPISRDEEMRRLEPVLAAVVALGISVSIDSMKSPVVEWALGNAAAIANDVWGLQRDPDMARVVAARNAPVVVMHNRDKP
DGTLDIMRDITAFFERSLKIAAQAGIPASRIILDPGIGFGKTPEQSMIALARLGELQTFGLPVLVGASRKRFISMVTPSE
PQQRLGGSLAAHLIAARSGARIIRTHDVAETVQALRVAHAIETATQPGSFEP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 2e-27 45
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 2e-27 45
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 2e-27 45
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 1e-27 44
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 1e-27 44
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 2e-27 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nwi_2233 YP_318839.1 dihydropteroate synthase AM180355.1.gene1650. Protein 6e-43 47
Nwi_2233 YP_318839.1 dihydropteroate synthase CP000647.1.gene3624. Protein 5e-34 44
Nwi_2233 YP_318839.1 dihydropteroate synthase DQ464881.1.gene2.p01 Protein 2e-27 44
Nwi_2233 YP_318839.1 dihydropteroate synthase CP001138.1.gene3456. Protein 2e-33 43
Nwi_2233 YP_318839.1 dihydropteroate synthase NC_002516.2.881715.p Protein 1e-33 43
Nwi_2233 YP_318839.1 dihydropteroate synthase NC_002695.1.916103.p Protein 2e-33 42
Nwi_2233 YP_318839.1 dihydropteroate synthase CP002695.1.gene1085. Protein 8e-30 42
Nwi_2233 YP_318839.1 dihydropteroate synthase CP004022.1.gene3451. Protein 9e-34 42
Nwi_2233 YP_318839.1 dihydropteroate synthase NC_011586.7045137.p0 Protein 5e-20 42
Nwi_2233 YP_318839.1 dihydropteroate synthase NC_010410.6003232.p0 Protein 5e-20 42
Nwi_2233 YP_318839.1 dihydropteroate synthase NC_011595.7059722.p0 Protein 5e-20 42
Nwi_2233 YP_318839.1 dihydropteroate synthase CP000034.1.gene3358. Protein 2e-32 42
Nwi_2233 YP_318839.1 dihydropteroate synthase CP000675.2.gene3019. Protein 2e-36 42