Gene Information

Name : Tbd_2039 (Tbd_2039)
Accession : YP_315797.1
Strain : Thiobacillus denitrificans ATCC 25259
Genome accession: NC_007404
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 2128195 - 2128698 bp
Length : 504 bp
Strand : -
Note : -

DNA sequence :
ATGAGCGGGACGGGGCAGCCGCGCGTGAGCGTCATCGCCGCGCTGGCAAAGAATCGCGTCATCGGCATCGAGAACCGGCT
GCCGTGGCGTCTGCCCGAAGACCTCGCCCACTTCAAGGCGCTGACGCTCGACCATCCCGTCCTGATGGGGCGCAAGACCT
TCGAGTCGCTCGGGCGGCCCTTGCCGCGGCGCACCAACGTCGTCATCACCCGCAACGCCGACTACCGGCCCGACGGCTGC
CTCGTCGCGGCGTCGATGCCGGCGGCGATCGCGCTATGCCAGGGCGCCGACGAAATCTTCTTCATCGGCGGCGCCGAGCT
CTATGCGCAGGCGATTCCGCTCGCCGATCGCCTGTATCTGACCGAAGTCGACGCCGAGCCCGAGGGCGATGCCTGGTTTC
CCGAGTTCGACCGGGCGGCGTTCCGCGAAATCTCGCGCGCCTCGCACGTGGGCGAGAAAGGCGACGTGCTGCGCTTCGAC
TTCGTCGTGTACGAACGCCGCTGA

Protein sequence :
MSGTGQPRVSVIAALAKNRVIGIENRLPWRLPEDLAHFKALTLDHPVLMGRKTFESLGRPLPRRTNVVITRNADYRPDGC
LVAASMPAAIALCQGADEIFFIGGAELYAQAIPLADRLYLTEVDAEPEGDAWFPEFDRAAFREISRASHVGEKGDVLRFD
FVVYERR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
folA-2 YP_189146.1 dihydrofolate reductase Not tested ¥ÕSP¥â Protein 1e-23 43
dfrA5 AET25387.1 dihydrofolate reductase Not tested PAGI-2(C) Protein 3e-14 42
dfrA5 AFG30110.1 dihydrofolate reductase Not tested PAGI-2 Protein 3e-14 42
unnamed AEL12695.1 DfrA5 Not tested AbaR21 Protein 2e-15 42
dfrA1 ADZ05803.1 trimethoprim-insensitive dihydrofolate reductase Not tested AbaR3 Protein 2e-15 42
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 1e-28 41