Gene Information

Name : Tbd_1603 (Tbd_1603)
Accession : YP_315361.1
Strain : Thiobacillus denitrificans ATCC 25259
Genome accession: NC_007404
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis/type III secretory pathway ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1688374 - 1689780 bp
Length : 1407 bp
Strand : +
Note : -

DNA sequence :
ATGAACACCCACGTGCACGCCGCCCGCTGGCAAGCCTACCTGCAAGACTGCACCGAACTGCTCGCGATCGCCGAGCCGAT
GCGGCTGTCCGGGCGGATTACGCGCGTCGCGGGACTCGTGATGGAGGCGGTGGGCTTGAAGCTTCCGGTCGGCAGCGCCT
GTACCGTGCCGCTGCCCAACGGCTCGCACCTCGAAGCCGAGGTCGTCGGGTTCGAAGGCGAGCGCTTGTTCCTGATGCCG
CAGAGCGACGTCGAGGGCATCGTCCCGGGCGCCCGGGTGTTTCCGGTCGAAGTCATCCCCACTTTGCCTGGCTTGGGCCA
GGTCAATCATCCCCGGCGACGCCCGAGCGATCGCACGCGCCACCTGCCCGTGGGCGAGGTCCTGCTGGGCCGCGTGCTCG
ACAGCAACGGGCGCCCACTCGATGGCCTCGGCTCGGTCCATACCTCGGCGACAGCACCGCTCAACAACCGCGCGGCGAAC
CCGCTCTCGCGCGCCCCGATCAGCGAGATCCTCGACGTCGGCGTGCGCGCGATCAACAGCATGCTGACGATCGGTCGCGG
CCAGCGCATGGGCCTCTTCGCCGGCTCGGGCGTCGGCAAGAGCGTGCTACTCGGCATGATGGCGCGCTACACCAGCGCCG
ACGTGATCGTCGTCGGCCTGATCGGCGAACGCGGCCGCGAAGTAAAGGAATTCATCGAGCAAATCCTCGGCGAAGAAGGC
CTGGCCCGCGCGGTCGTCGTCGCCGCCCCGGCCGACACGCCGCCGCTCATGCGTCTGCAAGGGGCGGCCTACGCCACGGC
GATCGCCGAGCATTTCCGCGACGAGGGCAAGAACGTCTTGCTGATCATGGATTCGCTGACGAGATATGCCATGGCGCAGC
GCGAAATCGCGCTCGCGATCGGCGAGCCGCCGGCGACAAAGGGCTATCCGCCGTCGGTTTTCGCCAAGCTGCCGGCGCTG
GTCGAACGCGCCGGCAACGGCAAGCCGGGCGGCGGGTCGATCACTGCCTTTTACACCGTGCTCACCGAGGGCGACGACCA
GCAGGACCCGATCGCCGACTCGGCGCGCGCGATCCTCGACGGCCATATCGTGCTGTCGCGCGACCTCGCCGAAAGCGGCC
ACTACCCGGCGATCGACATCGAGCAATCGATCAGCCGCGCGATGCACGGCATCACGAGCGCGGCGCACCAGCAGATGGCG
CGCCGCCTGAAGAAGCTCTATTCGCGTTACGCGCGCAGCCGCGACCTGATCAACGTCGGCGCCTATGCCCCCGGGACCGA
TCCGCTGCTCGACGAGGCGATCCGCCTGCAGGAGGGCATCGAGGCCTTCCTCCAGCAGAACATCCCCGAACGCGCGGGCG
TCGAGGAGAGCCTGGCCGCGTTGTCCACCCTCTTCCCGTCCACCTGA

Protein sequence :
MNTHVHAARWQAYLQDCTELLAIAEPMRLSGRITRVAGLVMEAVGLKLPVGSACTVPLPNGSHLEAEVVGFEGERLFLMP
QSDVEGIVPGARVFPVEVIPTLPGLGQVNHPRRRPSDRTRHLPVGEVLLGRVLDSNGRPLDGLGSVHTSATAPLNNRAAN
PLSRAPISEILDVGVRAINSMLTIGRGQRMGLFAGSGVGKSVLLGMMARYTSADVIVVGLIGERGREVKEFIEQILGEEG
LARAVVVAAPADTPPLMRLQGAAYATAIAEHFRDEGKNVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPAL
VERAGNGKPGGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRDLAESGHYPAIDIEQSISRAMHGITSAAHQQMA
RRLKKLYSRYARSRDLINVGAYAPGTDPLLDEAIRLQEGIEAFLQQNIPERAGVEESLAALSTLFPST

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-69 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-69 49
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-81 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 5e-81 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-82 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-82 47
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-81 47
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-68 46
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-75 46
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-77 46
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-77 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-73 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-72 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-66 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-66 46
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-66 46
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-66 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-66 46
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-81 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-81 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-66 45
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-77 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 6e-71 45
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-60 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-69 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-72 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-72 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 8e-72 43
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-71 43
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-72 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 5e-67 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 5e-67 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-61 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-61 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-61 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-61 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-75 42
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-72 42
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-72 42
escN AAK26715.1 EscN Virulence LEE Protein 3e-72 42
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-72 42
escN AAL57542.1 EscN Virulence LEE Protein 3e-72 42
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-72 42
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-72 42
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-72 42
escN AAC38383.1 EscN Virulence LEE Protein 9e-72 42
escN AAC31513.1 L0034 Virulence LEE Protein 4e-72 42
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-72 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-55 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-54 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG2499 Protein 6e-142 68
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG2331 Protein 3e-129 64
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG1254 Protein 3e-119 61
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0048 Protein 6e-82 47
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0390 Protein 2e-78 46
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG2144 Protein 4e-80 46
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0515 Protein 2e-66 46
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0192 Protein 9e-80 45
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG1778 Protein 4e-61 45
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0555 Protein 1e-61 43
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0812 Protein 2e-72 42
Tbd_1603 YP_315361.1 flagellar biosynthesis/type III secretory pathway ATPase FliI VFG0730 Protein 5e-72 42