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Name : spa40 (SSON_P117) Accession : YP_313372.1 Strain : Genome accession: NC_007385 Putative virulence/resistance : Virulence Product : surface presentation of antigens protein SpaS Function : - COG functional category : N : Cell motility COG ID : COG1377 EC number : - Position : 107618 - 108646 bp Length : 1029 bp Strand : + Note : component of the Mxi-Spa secretion machinery; Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins DNA sequence : ATGGCAAATAAAACAGAAAAGCCGACACCTAAAAAACTAAAGGATGCCGCAAAAAAAGGACAGTCATTTAAATTTAAGGA TTTAACGACTGTTGTTATTATTCTGGTAGGGACATTTACTATAATATCATTCTTTTCCTTAAGTGATGTAATGCTCTTAT ACAGATATGTAATAATTAATGACTTCGAAATTAATGAGGGTAAATACTTTTTTGCAGTGGTTATTGTCTTTTTTAAGATA ATTGGCTTCCCACTTTTTTTCTGTGTTCTTTCGGCTGTGTTGCCAACATTGGTTCAAACAAAGTTTGTTCTTGCGACTAA AGCTATCAAGATTGATTTTTCAGTATTAAACCCTGTTAAAGGGTTAAAAAAAATATTTAGTATAAAGACAATAAAAGAAT TTTTCAAAAGCATTCTGCTTCTTATTATTCTAGCATTAACAACCTATTTCTTTTGGATTAATGACCGAAAAATAATTTTT TCTCAGGTGTTTTCTAGTGTTGATGGCTTATATCTTATTTGGGGGGGGCTGTTTAAGGATATAATATTATTTTTCTTGGC ATTTTCTATTTTTGTTATTATTCTTGACTTTGTGATTGAGTTCATTTTATACATGAAAGATATGATGATGGATAAACAGG AGATAAAAAGAGAATATATAGAGCAAGAGGGACACTTTGAGACAAAGTCGAGAAGGCGTGAGTTGCATATCGAGATTCTT TCAGAGCAGACTAAATCTGATATACGTAATTCAAAATTAGTGGTAATGAACCCGACTCATATTGCAATTGGTATTTATTT TAATCCAGAAATAGCGCCTGCACCTTTTATTTCTCTCATTGAAACTAACCAGTGTGCCTTGGCTGTCAGAAAATATGCAA ATGAAGTTGGTATACCAACTGTGCGTGATGTGAAATTAGCTAGAAAACTATATAAAACACATACAAAATATAGTTTTGTT GATTTTGAACACTTGGATGAAGTCCTACGTCTTATTGTTTGGCTTGAGCAGGTTGAAAACACTCATTAA Protein sequence : MANKTEKPTPKKLKDAAKKGQSFKFKDLTTVVIILVGTFTIISFFSLSDVMLLYRYVIINDFEINEGKYFFAVVIVFFKI IGFPLFFCVLSAVLPTLVQTKFVLATKAIKIDFSVLNPVKGLKKIFSIKTIKEFFKSILLLIILALTTYFFWINDRKIIF SQVFSSVDGLYLIWGGLFKDIILFFLAFSIFVIILDFVIEFILYMKDMMMDKQEIKREYIEQEGHFETKSRRRELHIEIL SEQTKSDIRNSKLVVMNPTHIAIGIYFNPEIAPAPFISLIETNQCALAVRKYANEVGIPTVRDVKLARKLYKTHTKYSFV DFEHLDEVLRLIVWLEQVENTH |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ECs3721 | NP_311748.1 | surface presentation of antigens protein SpaS | Not tested | LIM | Protein | 3e-72 | 52 |
| spaS | YP_217806.1 | surface presentation of antigens protein SpaS | Virulence | SPI-1 | Protein | 3e-67 | 50 |
| spaS | NP_457281.1 | secretory protein (associated with virulence) | Virulence | SPI-1 | Protein | 4e-68 | 50 |
| spaS | NP_806490.1 | surface presentation of antigens protein SpaS | Virulence | SPI-1 | Protein | 4e-68 | 50 |
| spaS | NP_461808.1 | surface presentation of antigens protein SpaS | Virulence | SPI-1 | Protein | 1e-68 | 50 |
| spaS | AAS66868.1 | SpaS | Not tested | SSR-2 | Protein | 3e-71 | 47 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| spa40 | YP_313372.1 | surface presentation of antigens protein SpaS | VFG1015 | Protein | 2e-142 | 99 |
| spa40 | YP_313372.1 | surface presentation of antigens protein SpaS | VFG0548 | Protein | 6e-69 | 50 |
| spa40 | YP_313372.1 | surface presentation of antigens protein SpaS | VFG1770 | Protein | 9e-50 | 41 |
| spa40 | YP_313372.1 | surface presentation of antigens protein SpaS | VFG2452 | Protein | 8e-56 | 41 |
