Gene Information

Name : spaP (SSON_P115)
Accession : YP_313370.1
Strain :
Genome accession: NC_007385
Putative virulence/resistance : Virulence
Product : surface presentation of antigens protein SpaP
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4790
EC number : -
Position : 105916 - 106566 bp
Length : 651 bp
Strand : +
Note : component of the Mxi-Spa secretion machinery; part of a type III secretory system probably involved in invasion into eukaryotic cells

DNA sequence : 
ATGCTGAGTGACATGTCCCTCATCGCTACACTTTCTTTTTTTACGCTATTACCATTTTTAGTTGCTGCTGGTACCTGTTA
TATAAAGTTTTCTATTGTTTTTGTAATGGTACGAAATGCACTTGGTTTGCAGCAGGTTCCATCAAATATGACTCTCAATG
GTATTGCATTGATTATGGCTTTGTTCGTGATGAAACCCATTATTGAAGCTGGTTATGAAAATTATCTAAATGGCCCTCAA
AAATTTGATACAATATCTGATATTGTCCGTTTTTCTGATTCTGGCTTGATGGAATATAAGCAATACTTGAAAAAGCATAC
AGATCTTGAGTTAGCACGTTTTTTCCAAAGGTCTGAAGAAGAAAATGCTGATTTAAAGAGTGCAGAGAATAATGATTATT
CATTGTTTTCCCTCTTGCCTGCATATGCGCTAAGTGAAATCAAAGATGCGTTCAAAATAGGTTTTTATTTATATTTGCCA
TTTGTTGTTGTTGATCTTGTTATTTCAAGCATTTTACTTGCACTTGGTATGATGATGATGAGTCCAATCACAATATCAGT
ACCAATAAAACTTGTATTATTTGTTGCGCTTGATGGGTGGGGTATCCTGTCTAAGGCCTTGATTGAACAATATATCAATG
TTCCTGCTTAG

Protein sequence : 
MLSDMSLIATLSFFTLLPFLVAAGTCYIKFSIVFVMVRNALGLQQVPSNMTLNGIALIMALFVMKPIIEAGYENYLNGPQ
KFDTISDIVRFSDSGLMEYKQYLKKHTDLELARFFQRSEEENADLKSAENNDYSLFSLLPAYALSEIKDAFKIGFYLYLP
FVVVDLVISSILLALGMMMMSPITISVPIKLVLFVALDGWGILSKALIEQYINVPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaP YP_217809.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 9e-55 61
spaP NP_461811.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 9e-55 61
spaP NP_311752.1 surface presentation of antigens protein SpaP Not tested LIM Protein 1e-55 61
spaP NP_806493.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 2e-54 60
spaP NP_457284.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 2e-54 60
epaP AAZ31293.1 EpaP Virulence ETT2 Protein 5e-54 59
spaP AAS66865.1 SpaP Not tested SSR-2 Protein 4e-57 59
ysaR AAS66846.1 YsaR Not tested SSR-1 Protein 1e-50 58
escR AAC31528.1 L0049 Virulence LEE Protein 2e-33 44
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 2e-33 44
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 3e-33 44
escR AAK26700.1 EscR Virulence LEE Protein 2e-33 44
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 3e-33 44
escR AAL57527.1 EscR Virulence LEE Protein 2e-33 44
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 3e-33 44
escR CAC81847.1 EscR protein Virulence LEE II Protein 2e-33 44
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 3e-33 44
escR CAI43889.1 EscR protein Virulence LEE Protein 2e-33 44
escR AAC38369.1 EscR Virulence LEE Protein 1e-32 44
ECs4583 NP_312610.1 type III secretion system protein Virulence LEE Protein 2e-33 44
lscR AAO18040.1 LscR Virulence TTSS locus Protein 4e-31 43
unnamed AAL06354.1 EscR Virulence LEE Protein 1e-30 43
hrcR AAP34349.1 HrcR Virulence Hrp PAI Protein 4e-28 41
hrcR BAB07862.1 HrcR Virulence Hrp PAI Protein 4e-28 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaP YP_313370.1 surface presentation of antigens protein SpaP VFG1012 Protein 3e-90 99
spaP YP_313370.1 surface presentation of antigens protein SpaP VFG0551 Protein 3e-55 61
spaP YP_313370.1 surface presentation of antigens protein SpaP VFG2455 Protein 8e-54 58
spaP YP_313370.1 surface presentation of antigens protein SpaP VFG1773 Protein 4e-54 57
spaP YP_313370.1 surface presentation of antigens protein SpaP VFG0394 Protein 7e-33 46
spaP YP_313370.1 surface presentation of antigens protein SpaP VFG0827 Protein 1e-33 44
spaP YP_313370.1 surface presentation of antigens protein SpaP VFG0715 Protein 5e-33 44
spaP YP_313370.1 surface presentation of antigens protein SpaP VFG0188 Protein 4e-32 43