Gene Information

Name : mxiA (SSON_P109)
Accession : YP_313364.1
Strain :
Genome accession: NC_007385
Putative virulence/resistance : Virulence
Product : MxiA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 99964 - 102030 bp
Length : 2067 bp
Strand : +
Note : innermembrane protein; component of the Mxi-Spa secretion machinery

DNA sequence :
ATGAAAGTGATCCAGTCTTTTCTTAAGCAAGTAAGTACTAAGCCTGAATTAATTATATTAGTGCTTATGGTTATGATCAT
TGCTATGTTGATCATACCATTACCTACATACCTTGTTGATTTTTTAATAGGGCTTAATATTGTACTTGCTATTCTCGTTT
TTATGGGATCATTTTATATTGAAAGAATATTGAGTTTTTCTACATTCCCTTCGGTTTTGTTGATAACGACATTATTTCGT
CTCGCTTTATCAATAAGTACTAGTCGACTAATTTTAGTTGATGCGGATGCGGGTAAAATTATTACTACATTTGGCCAGTT
TGTCATTGGTGATAGTCTGGCTGTAGGTTTTGTTATTTTTTCAATAGTAACTGTTGTGCAGTTCATTGTTATAACAAAAG
GATCTGAAAGGGTTGCGGAGGTAGCTGCTCGCTTTTCTCTTGACGGTATGCCGGGGAAACAAATGAGCATTGATGCGGAT
TTAAAGGCTGGAATTATTGATGCCGCAGGAGCTAAAGAAAGACGCAGTATTCTGGAACGTGAGAGTCAATTGTATGGTTC
ATTTGATGGAGCAATGAAGTTCATTAAAGGTGATGCAATTGCTGGCATCATTATTATTTTTGTCAATTTAATAGGAGGTA
TTTCTGTTGGTATGAGTCAACATGGAATGTCCCTATCTGGTGCATTATCTACTTATACCATACTAACTATTGGTGACGGA
TTGGTCTCTCAGATTCCTGCTCTGTTAATTTCTATAAGTGCAGGATTTATCGTTACAAGAGTTAATGGTGATAGCGATAA
TATGGGACGTAACATAATGTCCCAGATATTTGGGAATCCTTTTGTTCTCATTGTTACATCAGCTCTTGCCTTGGCGATAG
GGATGTTGCCAGGTTTTCCGTTTTTTGTTTTTTTCCTGATAGCAGTTACTTTGACGGCTTTATTCTATTATAAAAAGGTC
GTAGAAAAAGAAAAAAGTCTGTCTGAGTCTGATTCTAGTGGCTATACTGGTACATTTGATATTGATAATAGCCATGACTC
ATCTTTGGCAATGATAGAAAATCTGGATGCTATTAGTTCAGAAACCGTTCCTTTAATTTTATTATTTGCCGAAAATAAGA
TAAATGCAAATGATATGGAAGGTCTTATTGAAAGGATAAGAAGTCAGTTCTTTATTGATTATGGTGTCAGGCTTCCAACT
ATTTTATATAGAACAAGCAATGAGCTTAAGGTCGATGATATTGTTTTGTTAATAAATGAGGTGCGTGCCGATAGTTTTAA
TATATATTTTGACAAAGTGTGTATTACAGATGAAAATGGAGATATAGATGCTCTAGGTATTCCTGTTGTTTCAACTTCAT
ATAATGAACGTGTTATTTCTTGGGTAGACGTTTCATATACAGAAAATCTAACTAATATTGATGCTAAAATTAAAAGTGCT
CAAGATGAATTTTATCACCAGTTGTCACAAGCTTTATTAAACAACATAAATGAGATTTTTGGTATACAAGAAACAAAAAA
TATGTTAGATCAGTTTGAAAATCGGTATCCTGATCTATTAAAGGAAGTCTTCCGACATGTGACTATACAGAGAATTTCTG
AGGTATTACAAAGATTGCTTGGAGAAAATATTTCTGTTCGCAATTTAAAACTTATTATGGAGTCTTTGGCGCTTTGGGCT
CCCAGAGAAAAAGATGTCATAACATTAGTTGAACATGTCCGTGCATCACTTTCTAGGTATATTTGTAGTAAAATAGCTGT
TTCTGGTGAGATTAAAGTTGTGATGCTTTCCGGATATATTGAGGATGCAATAAGAAAAGGGATAAGGCAAACCTCTGGTG
GCTCTTTCTTGAATATGGATATAGAGGTTTCGGATGAGGTAATGGAAACTTTAGCACATGCTTTGAGAGAATTGAGAAAT
GCAAAAAAAAATTTCGTTCTTTTGGTATCAGTAGATATACGTAGGTTTGTTAAAAGACTTATAGATAACAGATTTAAGAG
TATACTCGTTATATCGTATGCTGAGATTGATGAAGCATATACCATTAATGTATTAAAGACTATTTAG

Protein sequence :
MKVIQSFLKQVSTKPELIILVLMVMIIAMLIIPLPTYLVDFLIGLNIVLAILVFMGSFYIERILSFSTFPSVLLITTLFR
LALSISTSRLILVDADAGKIITTFGQFVIGDSLAVGFVIFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDAD
LKAGIIDAAGAKERRSILERESQLYGSFDGAMKFIKGDAIAGIIIIFVNLIGGISVGMSQHGMSLSGALSTYTILTIGDG
LVSQIPALLISISAGFIVTRVNGDSDNMGRNIMSQIFGNPFVLIVTSALALAIGMLPGFPFFVFFLIAVTLTALFYYKKV
VEKEKSLSESDSSGYTGTFDIDNSHDSSLAMIENLDAISSETVPLILLFAENKINANDMEGLIERIRSQFFIDYGVRLPT
ILYRTSNELKVDDIVLLINEVRADSFNIYFDKVCITDENGDIDALGIPVVSTSYNERVISWVDVSYTENLTNIDAKIKSA
QDEFYHQLSQALLNNINEIFGIQETKNMLDQFENRYPDLLKEVFRHVTIQRISEVLQRLLGENISVRNLKLIMESLALWA
PREKDVITLVEHVRASLSRYICSKIAVSGEIKVVMLSGYIEDAIRKGIRQTSGGSFLNMDIEVSDEVMETLAHALRELRN
AKKNFVLLVSVDIRRFVKRLIDNRFKSILVISYAEIDEAYTINVLKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 65
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 65
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 65
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 65
ECs3731 NP_311758.1 EivA Not tested LIM Protein 3e-178 61
invA AAS66860.1 InvA Not tested SSR-2 Protein 2e-170 57
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 2e-147 53
unnamed AAL06368.1 EscV Virulence LEE Protein 2e-99 42
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 5e-99 42
escV CAC81861.1 EscV protein Virulence LEE II Protein 3e-98 42
escV AAK26714.1 EscV Virulence LEE Protein 2e-98 42
escV AAL57541.1 EscV Virulence LEE Protein 2e-98 42
escV CAI43875.1 EscV protein Virulence LEE Protein 1e-98 42
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 2e-98 42
escV YP_003223476.1 translocator EscV Virulence LEE Protein 2e-98 42
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-96 41
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 2e-96 41
escV AAC38382.1 EscV Virulence LEE Protein 7e-99 41
escV AAC31514.1 L0035 Virulence LEE Protein 4e-99 41
escV NP_290269.1 hypothetical protein Virulence LEE Protein 5e-99 41
escV ACU09459.1 EscV protein Virulence LEE Protein 4e-99 41
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 5e-99 41
lssD AAO18050.1 LssD Virulence TTSS locus Protein 2e-113 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mxiA YP_313364.1 MxiA VFG1006 Protein 0.0 99
mxiA YP_313364.1 MxiA VFG0557 Protein 0.0 65
mxiA YP_313364.1 MxiA VFG1780 Protein 1e-149 51
mxiA YP_313364.1 MxiA VFG0729 Protein 4e-99 41
mxiA YP_313364.1 MxiA VFG0813 Protein 2e-99 41
mxiA YP_313364.1 MxiA VFG0384 Protein 9e-110 41