Gene Information

Name : SSON_2794 (SSON_2794)
Accession : YP_311642.2
Strain : Shigella sonnei Ss046
Genome accession: NC_007384
Putative virulence/resistance : Unknown
Product : insertion element IS2 transposase InsD
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG2801
EC number : -
Position : 2939070 - 2939975 bp
Length : 906 bp
Strand : -
Note : IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats

DNA sequence :
GTGGATAGCGCACGCGCCCTTATTGCCCGGGGATGGGGAGTAAGCTTAGTCAGCCGTTGTCTCCGGGTGTCGCGTGCGCA
GTTGCACGTCATTCTCAGACGAACCGATGACTGGATGGATGGCCGCCACAGTCGTCACACTGATGATACGGATGTGCTTC
TCCGTATACACCATGTTATCGGAGAGCTGCCCACGTATGGTTATCGTCGGGTATGGGCGCTGCTTCGCAGACAGGCAGAA
CTTGATGGTATGCCTGCGATCAATGCCAAACGTGTTTACCGGATCATGCGCCAGAATGCGCTGTTGCTTGAGCGAAAACC
TGCTGTACCGCCATCGAAACGGGCACATACAGGCAGAGTGGCTGTGAAAGAAAGTAATCAGCGATGGTGCTCTGACGGGT
TCGAGTTCCGCTGTGATAACGGAGAAAAACTGCGAGTCACGTTCGCGCTGGACTGCTGTGACCGTGAGGCACTGCACTGG
GCGGTCACTACGGGCGGCTTCAACAGTGAAACAGTACAGGACGTCATGCTGGGAGCGGTGGAACGCCGCTTCGGCAACGA
GCTTCCGGCGTCTCCAGTAGAGTGGCTGACGGATAATGGTTCATGCTACCGGGCTAATGAAACACGGCAGTTTGCCCGGA
TGTTGGGGCTTGAACCGAAGAGCACGGCGGTGCGGAGTCCGGAGAGTAACGGCATAGCAGAGAGCTTCGTGAAAACGATA
AAGCGTGACTACATCAGTGTCATGCCCAAACCAGACGGGTTAACGGCAGCAAAGAACCTTGCAGAGGCGTTCGAGCATTA
TAACGAATGGCATCCGCATAGTGCACTGGGTTATCGCTCGCCACGGGAATATCTACGGCAGCAAGCCAGTAATGGGTTAA
GTGATAACAGGTGTCTGGAAATATAG

Protein sequence :
MDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWMDGRHSRHTDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAE
LDGMPAINAKRVYRIMRQNALLLERKPAVPPSKRAHTGRVAVKESNQRWCSDGFEFRCDNGEKLRVTFALDCCDREALHW
AVTTGGFNSETVQDVMLGAVERRFGNELPASPVEWLTDNGSCYRANETRQFARMLGLEPKSTAVRSPESNGIAESFVKTI
KRDYISVMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQQASNGLSDNRCLEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAC39284.1 hypothetical protein Not tested LPA Protein 2e-121 99
S4061 NP_839230.2 insertion element IS2 transposase InsD Not tested SHI-2 Protein 7e-137 98
unnamed AAL67379.1 transposase-like protein Not tested PAI II CFT073 Protein 1e-118 97
S3189 NP_838472.2 insertion element IS2 transposase InsD Not tested SHI-1 Protein 1e-135 97
tnpF AAD44739.1 TnpF Not tested SHI-2 Protein 8e-119 97
insD YP_002414033.1 insertion element IS2 transposase InsD Not tested Not named Protein 2e-136 97
S4050 NP_839218.2 insertion element IS2 transposase InsD Not tested SHI-2 Protein 1e-136 97
SF3708 NP_709447.1 IS2 transposase TnpB Not tested SHI-2 Protein 1e-136 97
SF3721 NP_709460.1 IS2 transposase TnpB Not tested SHI-2 Protein 1e-136 97
SF2985 NP_708759.1 insertion element IS2 transposase InsD Not tested SHI-1 Protein 9e-117 96
ECO111_3773 YP_003236109.1 putative IS2 transposase InsAB Not tested LEE Protein 4e-122 95
aec49 AAW51732.1 Aec49 Not tested AGI-3 Protein 6e-122 84
unnamed CAC39283.1 hypothetical protein Not tested LPA Protein 6e-84 62
c5197 NP_757045.1 transposase insD Not tested PAI II CFT073 Protein 6e-62 60
insD YP_854263.1 IS2 transposase Not tested PAI I APEC-O1 Protein 1e-65 60
insD AAZ04432.1 IS2 transposase Not tested PAI I APEC-O1 Protein 8e-66 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SSON_2794 YP_311642.2 insertion element IS2 transposase InsD VFG1732 Protein 8e-137 97
SSON_2794 YP_311642.2 insertion element IS2 transposase InsD VFG0621 Protein 6e-137 97
SSON_2794 YP_311642.2 insertion element IS2 transposase InsD VFG0608 Protein 6e-137 97
SSON_2794 YP_311642.2 insertion element IS2 transposase InsD VFG0649 Protein 4e-117 96