Gene Information

Name : yfcU (SSON_2394)
Accession : YP_311272.1
Strain : Shigella sonnei Ss046
Genome accession: NC_007384
Putative virulence/resistance : Virulence
Product : PapC-like porin protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 2524198 - 2526840 bp
Length : 2643 bp
Strand : -
Note : involved in fimbrial biogenesis; Code: NU; COG: COG3188

DNA sequence :
ATGCCTGACCATTCTCTTTTTCGATTACGGATTCTTCCGTGGTGCATTGCGCTGGCAATGTCAGGGAGTTATAGCAGTGT
CTGGGCTGAAGACGACATTCAGTTTGATTCCCGTTTTCTGGAATTAAAAGGCGACACAAAAATTGATCTGAAGCGTTTTT
CCAGCCAGGGATATGTTGAGCCCGGAAAATACAATTTACAGGTTCAACTAAATAAACAGCCATTGGCGGAAGAGTACGAT
ATTTACTGGTATGCTGGTGAAGATGACGCGAGCAAAAGCTATGCTTGTCTGACACCGGAACTGGTAGCGCAGTTTGGTTT
AAAAGAAGACGTGGCGAAAAATCTGCAATGGAGCCACGATGCTAAATGCCTGAAATCCGGTCAACTGGAAGGCATGGAAA
TTAAGGCTGATTTAAGCCAGTCCGCATTAGTCATTTCACTGCCACAGGCTTACCTCGAATATACTTATCCCGACTGGGAT
CCGCCTTCACGTTGGGATGACGGCATCTCCGGGATCGTCGCGGACTACAGCATCAACGCACAAACCCGGCACGAAGAAAA
TGGCGGTGATGATAGTAACGAGATCAGCGGCAACGGGACGGTCGGGGTTAACCTGGGGCCGTGGCGTATGCGTGCTGACT
GGCAGACTAACTATCAACATACTCGCAGTAATGATGACGATGAATTCAGCGGCGATGAAACTCAAAAAAAATGGGAGTGG
AGTCGCTACTATGCCTGGCGGGCGTTACCATCATTAAAAGCCAAACTGGCGCTGGGCGAGGATTACCTCAGATCCGATAT
TTTTGATGGTTTTAACTATGTTGGTGGCAGTGTCAGTACTGACGATCAAATGTTGCCTCCCAATCTGCGCGGCTACGCGC
CAGACATTTCCGGCGTGGCACACACCACAGCAAAAGTGACCGTCAGCCAGATGGGGCGTGTGATTTACGAAACGCAGGTT
CCGGCTGGACCGTTTCGTATTCAGGATCTTGGTGATTCTGTCTCCGGTACGTTGCATATTCGCATTGAAGAACAGAACGG
CCAGGTGCAGGAATATGACATCAGCACCGCCTCGATGCCATACCTCACTCGTCCAGGTCAGGTTCGCTATAAGATCATGA
TGGGCCGTCCGCAAGAGTGGGGACACCATGTCGAGGGTGAATTTTTTTCTGGTGCTGAAGCTTCCTGGGGGATCGCTAAC
GGCTGGTCGTTATATGGCGGCGCACTGGGAGATGAAAACTATCAGTCTGCGGCGCTTGGCGTCGGTCGCGATTTGTCTAC
ATTCGGCGCGGTCGCGTTTGATGTTACTCACTCGCACACCAAACTGGATAAAGACACCGCTTATGGCAAAGGTTCGCTGG
ACGGTAACTCCTTCCGTGTGAGTTATTCCAAAGACTTTGACCAGCTCAACAGCCGCGTTACTTTTGCTGGATATCGCTTC
TCGGAAGAGAACTTTATGACCATGAGCGAGTATCTGGATGCCAGTGACAGCGGAATGGTACGCACGGGCAACGACAAAGA
GATGTACACTGCCACTTATAACCAGAACTTCCGCGATGCGGGTGTTTCGGTTTATCTCAACTATACCCGCCATACCTACT
GGGATCGCGAGGAGCAGACAAACTACAACATCATGCTCTCGCACTATTTCAATATAGGCAGTATTCGTAATGTCAGCATC
TCGATGACTGGCTACCGTTACGAGTATGACAACCAGGCCGACAAAGGCATGTACATTTCGCTCAGTATGCCGTGGGGTGA
CAACAGTACCGTTAGCTATAACGGTAACTATGGCAGTGGGACGGACAGCAGTCAGGTCGGTTATTTCAGCCGTGTCGATG
ACGCGACTCACTATCAGTTGAACGTCGGCACCAGTGACAAACACACCAGCGTTGACGGCTATTACAGCCATGATGGTTCG
CTGGCGCAGGTTGACCTCAGTGCGAACTACCATGAAGGGCAATACACCTCTGCGGGCTTGTCGTTACAGGGCGGCGCAAC
GCTTACTGCCCACGGTGGCGCACTTCACCGTACCCAGAATATGGGCGGGACACGCTTGTTGATTGATGCCGATGGCGTTG
CCGATGTTCCGGTAGAAGGTAACGGTGCTGCTGTTTATACCAATATGTTTGGTAAAGCCGTCGTTTCTGACGTCAATAAC
TATTACCGCAATCAGGCGTATATCGACCTCAACAAACTGCCGGAAAACGCCGAAGCAACCCAGTCGGTGGTACAAGCCAC
GCTAACTGAAGGGGCGATTGGCTACCGCAAATTTGCCGTCATCAGTGGTCAAAAAGCGATGGCGGTGCTGCGTTTACAAG
ACGGCAGCCATCCTCCGTTTGGCGCAGAAGTAAAAAATGATAACGAGCAGACAGTGGGCCTTGTCGATGATGACGGCAAT
GTTTATCTGGCTGGGGTGAAACCTGGCGAACACATGAGTGTGTTCTGGAGTGGTGTTGCGCATTGCGATATCAACCTGCC
GGACCCGCTGCCTGCCGATCTGTTTAACGGCTTGTTACTGCCATGCCAGCATAAAGGCAACGTCGCGCCGGTTGTTCCTG
ATGACATAAAGCCTGTCATTCAGGAGCAGACGCAACAGGTGACACCCACCAATCCCCCTGTTTCTGTTTCAGCTAACCAA
TAA

Protein sequence :
MPDHSLFRLRILPWCIALAMSGSYSSVWAEDDIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLAEEYD
IYWYAGEDDASKSYACLTPELVAQFGLKEDVAKNLQWSHDAKCLKSGQLEGMEIKADLSQSALVISLPQAYLEYTYPDWD
PPSRWDDGISGIVADYSINAQTRHEENGGDDSNEISGNGTVGVNLGPWRMRADWQTNYQHTRSNDDDEFSGDETQKKWEW
SRYYAWRALPSLKAKLALGEDYLRSDIFDGFNYVGGSVSTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQMGRVIYETQV
PAGPFRIQDLGDSVSGTLHIRIEEQNGQVQEYDISTASMPYLTRPGQVRYKIMMGRPQEWGHHVEGEFFSGAEASWGIAN
GWSLYGGALGDENYQSAALGVGRDLSTFGAVAFDVTHSHTKLDKDTAYGKGSLDGNSFRVSYSKDFDQLNSRVTFAGYRF
SEENFMTMSEYLDASDSGMVRTGNDKEMYTATYNQNFRDAGVSVYLNYTRHTYWDREEQTNYNIMLSHYFNIGSIRNVSI
SMTGYRYEYDNQADKGMYISLSMPWGDNSTVSYNGNYGSGTDSSQVGYFSRVDDATHYQLNVGTSDKHTSVDGYYSHDGS
LAQVDLSANYHEGQYTSAGLSLQGGATLTAHGGALHRTQNMGGTRLLIDADGVADVPVEGNGAAVYTNMFGKAVVSDVNN
YYRNQAYIDLNKLPENAEATQSVVQATLTEGAIGYRKFAVISGQKAMAVLRLQDGSHPPFGAEVKNDNEQTVGLVDDDGN
VYLAGVKPGEHMSVFWSGVAHCDINLPDPLPADLFNGLLLPCQHKGNVAPVVPDDIKPVIQEQTQQVTPTNPPVSVSANQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 5e-152 43
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 2e-150 43
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 1e-150 43
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 1e-151 43
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 1e-151 43
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 1e-151 43
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 5e-157 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfcU YP_311272.1 PapC-like porin protein VFG1548 Protein 3e-152 43
yfcU YP_311272.1 PapC-like porin protein VFG0884 Protein 6e-152 43
yfcU YP_311272.1 PapC-like porin protein VFG0895 Protein 4e-152 43