Gene Information

Name : serS (cbdb_A554)
Accession : YP_307654.1
Strain : Dehalococcoides sp. CBDB1
Genome accession: NC_007356
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 449918 - 451159 bp
Length : 1242 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATTTGAAATTTATAAGAGAAAATCCTGAACTGGTACGCAAGGCAGTGGCAGACCGGAATACCGATGCCCCCAT
TGATGAAATACTGGAACTGGATAACAGCCGCCGTAACCTCACTCAGGAATTGGATAACCTTCGTGCCAAACGCAAAATAA
TGGCCAAACAGAGGGATGAGACCGCCATTGAAGAGGGGCGGGTTTTACGCGGGCAGATAAGTACACTTGAGTCCGAACTT
TCACAGGTAGATGAAAAGCTGACTGACCGATTGCTCAGAGTACCCAATATTCCTGACCCGTCTGTGCCTGTTGGTAAAGA
TGAAAGCGAAAATGTAGTCCTTTATTACAGGGGAGAAAAACGCAATTTCAGTTTCACTCCCAAACCTCATTGGGAACTGG
GTGAAGCCCTGGATATTATAGACTTTGACCGGGGTATCAAACTTTCGGGTTCACGTTTCTATATCTTGAAAGGCGCGGGT
GCCCGCCTTCAAAGAGCCCTTATTGCCTTTATGTTAGACCTGCATACCCGAAAACACGATTATACCGAGATCTACCCCCC
CTATATGATAAAAAGAGAGTGTCTGGTAGCTTCGGGCAACCTGCCCAAATTTGCTGACAATCTCTATCATGACGCAGAGG
AAGACTACTGGTGGGTGCCTACCGCTGAAGCCCCCTTAACCAATCTGCACCGTGATGAAATACTCTCCGCAGAGCAGTTG
CCCATTCATTATGTAGCCTACACCGCCTGTTTCCGCCGTGAGAAAATGTCCGCCGGCAAGGATGTACGCGGCATTAAGCG
GCTGCATCAGTTTGACAAGGTTGAACTCTATAAATACTGCAAACCGGAAGATTCTTTTGCCGAACTGGAAAAGATGGTGG
CAGATGCGGAAGAAATAGCAGACGCCCTCAAAATACCCTACCGCCTTAAACAGCTGGTCACCGCTGATATAAGCTTCGGT
TCAGCCAAGTCTTATGATATTGAAATGTATTCACCCGGAGTTGACGAATGGCTGGAGGTTTCATCCTGTTCCAACTGCAC
AGACTTTCAGGGCAGGCGGGCTAATGTCCGCTTCCGCCGCACCTCCGAAGCCAAACCCGAATTCGTCCACACCCTGAACG
GATCAGGTCTGGCCCTGCCCAGAGTGATGATATCGGTTATAGAAAACTATCAGCAACCGGACGGAAGCATTGTAATTCCT
GAAGTACTCCGCCCGTTTATGGGAGTGGACGTTATCCGCTAG

Protein sequence :
MLDLKFIRENPELVRKAVADRNTDAPIDEILELDNSRRNLTQELDNLRAKRKIMAKQRDETAIEEGRVLRGQISTLESEL
SQVDEKLTDRLLRVPNIPDPSVPVGKDESENVVLYYRGEKRNFSFTPKPHWELGEALDIIDFDRGIKLSGSRFYILKGAG
ARLQRALIAFMLDLHTRKHDYTEIYPPYMIKRECLVASGNLPKFADNLYHDAEEDYWWVPTAEAPLTNLHRDEILSAEQL
PIHYVAYTACFRREKMSAGKDVRGIKRLHQFDKVELYKYCKPEDSFAELEKMVADAEEIADALKIPYRLKQLVTADISFG
SAKSYDIEMYSPGVDEWLEVSSCSNCTDFQGRRANVRFRRTSEAKPEFVHTLNGSGLALPRVMISVIENYQQPDGSIVIP
EVLRPFMGVDVIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-93 46