Gene Information

Name : clpA (cbdb_A1374)
Accession : YP_308336.1
Strain : Dehalococcoides sp. CBDB1
Genome accession: NC_007356
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1092779 - 1095217 bp
Length : 2439 bp
Strand : +
Note : -

DNA sequence :
ATGAGACAGGAAAAATTTACCGAACAAGCCCAGGAAGCCCTCAGCGCTTCACAGATGCTGGTACAGGAATATCAGCACAG
CCAATGGGATGTTGAACATGTACTGCTGGCTCTTGTCCGTCAGGAAAAAGGGCTGGTGGGTGAAATAATCAAAGAGCTGA
AACTAAGCTCCGAGGAAATAACCAAACAGCTGGTAGAGGCTTTGAAACGTTCGCCTAAAGCAGTAGGCGGCAATGTTCAG
ATATACCCCACCCCCCGCATTATCAGCCTGCTGCAAACCGCCAACAACGAAGCAGACCGCCTGCGGGATGAATTCATAGG
CACGGAACATCTGCTGGTAGCTATAGCAGGAGATACCCAGGGAGAATCTGCCCGCATCCTGAAGCATTTTGGTATTGATC
AGGAAAAAGTCTATTCCGCCCTCCAGAAAATAAGGGGCGGACACCGGGTGACTGATGCCAGAGCCGAAAGCAAATACAGG
GCACTGGCCAAATACAGCCGTGACCTTACCGAACTGGCTAAACAGGGCAAGATAGACCCGGTAATAGGCCGTGATCAGGA
AATCCGCCGGGTTATGCAGATACTCTCCCGCCGCACCAAGAACAACCCTGTGATAGTGGGGGAAGCAGGTGTAGGCAAAA
CTGCCATTGCCGAAGGGGTTGCCCAAAAAATTGCGGATAACGACGTACCCGAATCCCTGCGTGACCGCAAGGTAATGGCA
CTGGATATGGGTGCATTGGTTGCCGGAAGCAAGTTCCGGGGGGAGTTTGAAGAACGCCTCAAAGCCGTAATGGACGAAGT
GCGCCAATCTGCCGGTGAAATTATTTTGTTTATAGATGAAATCCATACCGTAGTCGGGGCAGGGGCAGCCGAGGGGGCTA
TTGATGCCTCAAACATGCTGAAGCCGGCCTTATCCAGGGGTGAACTCCAGACTATTGGGGCTACCACTCTGGATGACTAC
CGCAAATATATTGAAAAAGACACCGCTCTGGAGCGCCGCTTCCAGCCGGTATATGTGGAAGAACCTACAGTGGAACAAAC
TATTGAGATACTAAAGGGTATCAGACCCAAGTACGAAACCCACCACAAGCTGAAGATAAGTGACGCCGCTCTGGAGGCAG
CCGTCAGGCTGTCCAGCCGTTACATAACTGAACGCCAACTGCCCGATAAGGCTATAGACCTTATTGACGAAGCCGCAAGC
AAACTCCGTCTGGATAGCGAAAGCGCCCCGCCGGAAGTAAAGAAGCTGGAAAATGAATTTCGTCAGGCAGGCATTGAGGA
AGAAGCCGCCTCCCAACTGCAGGATTATGAAAAAGCGGCTGAACTCAAGGCTGAAAAAATACGCTTGGAAGAAAAGTTCA
ACACTGCCCGTGAGGAATGGCTGAAACAGGAGAAAATAGCCGAAGAAGTAACTGACAAACAGATAACCGAGCTGGTTTCC
TCTATGACCGGCATACCTGTCAGCCAGATGCTTGAAGGCGAGGCTTCCAAACTGCTGAATATGGAAGAGCGTATCCACGA
GCGGATGGTAGACCAGGAAGAAGCCGTAAAAGCCGTTGCCGAAGCTATCCGCCGCAGCAGGGCAGGTCTTAAAGACCCGC
GCCGCCCTATAGGCAGTTTCCTGTTTTTAGGCCCGACCGGGGTGGGCAAAACAGAACTGGCCCGAAGTCTGGCCTGGTTT
TTGTTTGACGATGAAACCGCCATGGTAAGGCTGGATATGTCCGAATATCAGGAAAAGCACACCGTATCCCGTCTGGTGGG
GGCACCTCCCGGATATGTGGGCTACGATGAAGGCGGGCAACTAACCGAATTGGTTCGCCGCCGCCCTTATCGGGTTATCC
TGCTGGATGAAATTGAAAAAGCCCATCCAGATGTCTACAATTCCTTGCTCCAGCTATTGGATGACGGCCGTCTGACAGAC
GGGCAGGGCAGAACAGTGGACTTTAAAAATACGGTCATTATAATGACCTCTAACGCAGGCATAGAAACCATAAAACGCGA
ATCTGCTCTGGGTTTCGCAGTCAGAACCGATGACACCAAAACCCGCCATGACAGCTATGAACGCATGAAAGACAAGGTCA
TGACCGAAGTCAAAAAGACCTTCCGTCCGGAGTTCATCAACCGGGTAGATGAAATAATTGTCTTCCACGAGCTGGCAGAG
GAACAGATACGCCAGATAGTAGATTTCATGATAAAAGACGTTTCCAAACGTCTTGAGGAACGCAAACTCAAACTGGAGCT
GACCGACGAGGCTAAGGGCTGGCTGGCCAAGGTGGGTTATGACCCGGCTTTCGGTGCCAGACCCCTTCGCAGAGCCATTG
AAAGATACGTGGAAAGCCCGCTGGCGGGCAAGCTGCTTCGCAATGAGTTTAGTGAAAATGCTACAATACTGGTGGACAAG
GCGGATGAAGCTTTGAGTTTTAGCCAAAAGGCCGCCTGA

Protein sequence :
MRQEKFTEQAQEALSASQMLVQEYQHSQWDVEHVLLALVRQEKGLVGEIIKELKLSSEEITKQLVEALKRSPKAVGGNVQ
IYPTPRIISLLQTANNEADRLRDEFIGTEHLLVAIAGDTQGESARILKHFGIDQEKVYSALQKIRGGHRVTDARAESKYR
ALAKYSRDLTELAKQGKIDPVIGRDQEIRRVMQILSRRTKNNPVIVGEAGVGKTAIAEGVAQKIADNDVPESLRDRKVMA
LDMGALVAGSKFRGEFEERLKAVMDEVRQSAGEIILFIDEIHTVVGAGAAEGAIDASNMLKPALSRGELQTIGATTLDDY
RKYIEKDTALERRFQPVYVEEPTVEQTIEILKGIRPKYETHHKLKISDAALEAAVRLSSRYITERQLPDKAIDLIDEAAS
KLRLDSESAPPEVKKLENEFRQAGIEEEAASQLQDYEKAAELKAEKIRLEEKFNTAREEWLKQEKIAEEVTDKQITELVS
SMTGIPVSQMLEGEASKLLNMEERIHERMVDQEEAVKAVAEAIRRSRAGLKDPRRPIGSFLFLGPTGVGKTELARSLAWF
LFDDETAMVRLDMSEYQEKHTVSRLVGAPPGYVGYDEGGQLTELVRRRPYRVILLDEIEKAHPDVYNSLLQLLDDGRLTD
GQGRTVDFKNTVIIMTSNAGIETIKRESALGFAVRTDDTKTRHDSYERMKDKVMTEVKKTFRPEFINRVDEIIVFHELAE
EQIRQIVDFMIKDVSKRLEERKLKLELTDEAKGWLAKVGYDPAFGARPLRRAIERYVESPLAGKLLRNEFSENATILVDK
ADEALSFSQKAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpA YP_308336.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0079 Protein 0.0 55
clpA YP_308336.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0080 Protein 7e-155 50