Gene Information

Name : Mbar_A0175 (Mbar_A0175)
Accession : YP_303740.1
Strain : Methanosarcina barkeri Fusaro
Genome accession: NC_007355
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 197824 - 199257 bp
Length : 1434 bp
Strand : -
Note : -

DNA sequence :
ATGCAAATTCCGGACCATAAAACAAAGATTGTCTGTACCATAGGCCCTGCTTCCTCTTCCGAAGAAGTGATCAGGAAACT
TGTGCTTGCTGGCATGAACGTGGCAAGGATCAATTTTTCCCACGGGAGCTTCGAAAGCCATAGCGAAGTAATCCAGAGAG
TCCGTAAGGTTGCAGAGGAGCTTGACAGGACAGTTGCGATTCTTGCCGACCTGCCAGGCCCGAAGATCCGTATAGGCAAA
CTGGAAAAAGAACCGATCATGCTCCATAAAGGAAACTCTGTGACCCTTACGGTTGCCGAAACTACAGGAAATGAGACACG
TATTCCTGTAAGCTACAAGCAACTTCCGGAAAGCGTGGTTCCAGGGAGCCTTATTTACTTAAGTGACGGTTTTATCCAGC
TTCGATGCCTGGAAGTTTCGGGAAAAGATGTGCTTTGTGAGGTTCTTATCGGAGGGCAGCTCTATTCTCATAAAGGGCTA
AATCTACCAGGGGCAAAGATCTTAGTTGATTCTGTAACTGGAAAGGATCTTGAAATTCTTGGGTTTGCCCTTAGTAAAGG
GATCGACACTTTCAGCATTTCTTTCATAGAAAGTGCGGAAGATATTCGTAATGTCCGGAATTTTGCTGCAGCTAGAGGAA
AGTCTGTATATATTGTTTCTAAAATCGAACGCAGGCAAGCTGTAGAGAATATCCAGGACATTCTAAAAGAAACCGATGCT
CTCATGATTGCCAGAGGGGACCTCGGGGTTGAAATACCTATTCAGGAAGTTCCTTCAGTCCAGAAGGAACTTATCCATAG
TGCAAAACTTCTTGGAATTCCGGTAATTACAGCCACTCAAATGCTGGCTTCAATGACTGATAATATAAGGCCTACCCGCG
CAGAAGCAACCGATGTAGCCAACGCAATCCTTGACGGCACAGATGCGGTTATGCTTTCGGAAGAGACGGCAGTTGGTAAT
TATCCTGTGGAAGCTGTTGAAATGATGGCAAAAATTGCAAAAACCACAGAAGACTGGCGTTCCGGGACAAAATGGGGACT
AGATGCTATTATCAAGGGCATAACGGCAAGAGATATGTCAGTGGATGAGGTAATAACCCTCCAGGTGCATGAAGCCTTGC
AAAAGTTGCCGGTTGCGGCCGTACTGACTCCCACGAGAAGTGGAGCGACCCCCCGCAGGATCTCGCGCTTCAAGCCTGAT
ACCTGGATCCTTGCTTTCAGCCGTGTCCCGAGAACCTGCGGCTTCCTCTCTTTATCCTATGGCGTTTATCCTATCACTGT
GAATGAAAATATTGAAAGCTGGGAAAAAGAGACTACTGAGAAAGCCAAAGACCTTGGATTTGTAAAAAGCGGAGAGATTG
TTATTTTCACCCAGGGTCCATCTTCAGGAAGCCCCGGAGGCACAAATATGCTTAAAATCCTTACCCTTAAATAA

Protein sequence :
MQIPDHKTKIVCTIGPASSSEEVIRKLVLAGMNVARINFSHGSFESHSEVIQRVRKVAEELDRTVAILADLPGPKIRIGK
LEKEPIMLHKGNSVTLTVAETTGNETRIPVSYKQLPESVVPGSLIYLSDGFIQLRCLEVSGKDVLCEVLIGGQLYSHKGL
NLPGAKILVDSVTGKDLEILGFALSKGIDTFSISFIESAEDIRNVRNFAAARGKSVYIVSKIERRQAVENIQDILKETDA
LMIARGDLGVEIPIQEVPSVQKELIHSAKLLGIPVITATQMLASMTDNIRPTRAEATDVANAILDGTDAVMLSEETAVGN
YPVEAVEMMAKIAKTTEDWRSGTKWGLDAIIKGITARDMSVDEVITLQVHEALQKLPVAAVLTPTRSGATPRRISRFKPD
TWILAFSRVPRTCGFLSLSYGVYPITVNENIESWEKETTEKAKDLGFVKSGEIVIFTQGPSSGSPGGTNMLKILTLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-63 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mbar_A0175 YP_303740.1 pyruvate kinase VFG0479 Protein 9e-64 41