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Name : guaA (Ecaj_0074) Accession : YP_302723.1 Strain : Ehrlichia canis Jake Genome accession: NC_007354 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 116089 - 117669 bp Length : 1581 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGTCAAAAGTAGCAATTATTGATTTTGGGTCGCAATTTACGCAATTACTTGCTAGGAGAATAAGAGAACTAAATGTCTA TTGTGAAATTTTTACACCTGATGTGGAATTTGATCTTGTAAAAGACAGTAAGGCGTTTATTTTATCTGGAGGACCTAAAT CAGTTGCTAGTTTAGCGGAAATACCTAAAATTGTTCATAATATTATTGAGTTAAATAAGAAATCTTCAATTCCAGTGTTA GGTATATGCTATGGATTACAGCTTTTAAGTAATTATTTTAATTCAGCTATTGTATCTGATTGTAGTAAAGAATTTGGTAA AGCTACTTTGAATATTATAAAAGAATCAGAAATCACAAAAAATGTTTGGGAAGTAGGTAAAAGGGTTGATGTATGGATGA GCCATGCAGATAGTGTATATAATGTTCCTCGTGGTTTTGAAGTTATAGCATATAGTGTGTTGAAGAATGTAATTGCAATG ATATGCAATGAAGAAAGAAAAATCTACGGCATGCAGTTTCATCCTGAAGTATATCACACTACTGATGGTATAGCATTGCT TAGTAATTTTATAAAGATAGCAGGGTGTAAAACTGATTGGACAATGAATTCCTTTTTGGATGAGCAACAACGTGTTATAA AAAAGCAAGTAGGAGATAAAAAGGTAATAGCAGCTATTAGTGGTGGGGTTGACTCTAGTGTTGCTGCTGCTTTGACTTAT CGAGCCATAGGGGATCAATTGCACTGTATCTTTATTGATAATGGTCTGTTACGTTATAATGAAGCAGAAAAAATAAGTCA GTTATTAGTTAATCAATTTCAAATGCCTATCACTATTGTTGATAAATCATCAGTGTTTTTGAATAAACTTAAGTCTATTA CTGATCCAGAACAAAAACGGAAAATAATAGGAAAAACATTTATTGAAGTATTTGAAGGAGAGGCAAATAAAATAGGAGGA GTAGAATTTCTAATGCAGGGAACTATATACCCTGATGTCATAGAATCTGGTGGTGCTGTGGGAAAAGAAAGTGTAACTAT CAAGTCTCATCATAATGTTGGTGGATTACCTGATGTTATGAGACTGCAGCTTGTTGAGCCTCTAAAGTTGCTGTTTAAAG ATGAAGTTAGATTATTGGGAAAGGAGCTTGGAATATCAGATGAAATATTGATGCGCCATCCATTTCCAGGTCCTGGACTA GCAATTAGAATAATAGGTGAAGTTACTCAAGAAAAAATAAAAATGCTACAAGCTGCTGATGATATATATATCAATCTTAT AAAGAAGTACAACTTGTATAATATTATATGGCAGGCATTTGCAGTGATATTACCTGTGAAAACAGTAGGTGTTATGGGTG ATAGTAGGACTTATGGTTATACTTGTGCTTTAAGAGCTGTTACTTCTAGTGATGGTATGACTGCAGGCTGTTTCCCATTT GGTGTAGATACAGATACTAAGTTAATCTTTTATGAATTTTTGCAGGAAGTAAGTAATGCAATAGTAAATAATGTTGATGG GATTAATAGAGTAGTATATGACACTACATCTAAACCTCCAGCTACAATTGAATGGGAATAG Protein sequence : MSKVAIIDFGSQFTQLLARRIRELNVYCEIFTPDVEFDLVKDSKAFILSGGPKSVASLAEIPKIVHNIIELNKKSSIPVL GICYGLQLLSNYFNSAIVSDCSKEFGKATLNIIKESEITKNVWEVGKRVDVWMSHADSVYNVPRGFEVIAYSVLKNVIAM ICNEERKIYGMQFHPEVYHTTDGIALLSNFIKIAGCKTDWTMNSFLDEQQRVIKKQVGDKKVIAAISGGVDSSVAAALTY RAIGDQLHCIFIDNGLLRYNEAEKISQLLVNQFQMPITIVDKSSVFLNKLKSITDPEQKRKIIGKTFIEVFEGEANKIGG VEFLMQGTIYPDVIESGGAVGKESVTIKSHHNVGGLPDVMRLQLVEPLKLLFKDEVRLLGKELGISDEILMRHPFPGPGL AIRIIGEVTQEKIKMLQAADDIYINLIKKYNLYNIIWQAFAVILPVKTVGVMGDSRTYGYTCALRAVTSSDGMTAGCFPF GVDTDTKLIFYEFLQEVSNAIVNNVDGINRVVYDTTSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 1e-113 | 49 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 9e-114 | 49 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-113 | 48 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 7e-102 | 45 |
