Gene Information

Name : Ecaj_0454 (Ecaj_0454)
Accession : YP_303089.1
Strain : Ehrlichia canis Jake
Genome accession: NC_007354
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 662546 - 663817 bp
Length : 1272 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCATGATGTAGATTTTATAAAACGTAATCCAGAATTGTTTGATTACGCAATGCAAAATAGAAATTATGAAAAGGTTGC
TCAAAAAATTATAGAGCTGGATATAAAGAAAAAACAACTATTAACACAGTTATATTCTTTACAGAAGGAGCGTAATCAGA
TTACTCGAGAAATTGAAAAATTAAAGAAAGATGGTGTTAAATGTGATACTCAAATAGAATCTTCAAAGAATATAACAGAG
AAAATAAATGATATTAACAATATGATAAAAGAAGATTCTCAATTAATTGACCTTCTTAATGTGTTACCAAATGTACCAGA
TGATATAGTTCCTGTTGGAAAAGATGAGAGTAGTAATGTTGAGATAAGAAAACATGGGTATAAAAGAAATTTTGATTTTC
AAGTGAAAACTCATTATGAGTTAGGAGAAAAGTTAAATTTAATGGATTTTAAGCAAGCTGCAAAACTTTCTGGATCAAGA
TTTGTAATACTTAAAAATCAACTTGCACAATTAGATCGTGCTCTGGCTAATTTTATGTTAGACATTCATACTAAGGAATT
TGGCTATTCTGAGATATCTCATCCAATATTAGTGCATGAATCTGCAATGTACGGTGTAGGACAATTACCGAAATTTGCTG
ATGATTCATTTAAAACAACAGAAAATTTTCGGCTTGTCCCAACAAGTGAAGTAGCACTGACTAATTTAGTATCAGGCATG
AATATTAATTCATGTGACTTACCTATTAGATTGACTGCTTGTTCACCATGTTTTAGATTAGAAGCAGGAAGTGCTGGTAA
AGATACAAGAGGTATGATGCGGCAACACCAATTTAATAAAGTAGAGTTAGTTAGTATTGTTACTGAAGAACAGTCAGCAT
CAGAATTAGAAAGGATGGTACAAGTTGCTGAAGAAGTTTTAAAACGTTTAGAGTTACCATACAGAGTAATGATGTTGTGT
ACTGGAGATATGGGTTTTTCAGCAAGCATAACATATGATATTGAAGTGTGGGTACCAAGTCAAAATCGGTACCGAGAAAT
TTCAAGTTGTTCAAATTGTAAAGATTTTCAGGCACGTAGAATGAATACTAAGTATACTACTATAACTAATAATGTTAAAG
TTAGTAAATTTGCACATACATTAAATGGTTCTGCTCTAGCAATAGGAAGAACTATTATTGCGATCTTAGAAAATTATCAA
AATATGGATGGTTCTATAACAATACCACTTGCTTTAAGAAAGTATATGAATGATCAAGAATTTATAAAATAA

Protein sequence :
MHDVDFIKRNPELFDYAMQNRNYEKVAQKIIELDIKKKQLLTQLYSLQKERNQITREIEKLKKDGVKCDTQIESSKNITE
KINDINNMIKEDSQLIDLLNVLPNVPDDIVPVGKDESSNVEIRKHGYKRNFDFQVKTHYELGEKLNLMDFKQAAKLSGSR
FVILKNQLAQLDRALANFMLDIHTKEFGYSEISHPILVHESAMYGVGQLPKFADDSFKTTENFRLVPTSEVALTNLVSGM
NINSCDLPIRLTACSPCFRLEAGSAGKDTRGMMRQHQFNKVELVSIVTEEQSASELERMVQVAEEVLKRLELPYRVMMLC
TGDMGFSASITYDIEVWVPSQNRYREISSCSNCKDFQARRMNTKYTTITNNVKVSKFAHTLNGSALAIGRTIIAILENYQ
NMDGSITIPLALRKYMNDQEFIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-94 50