Gene Information

Name : Ecaj_0278 (Ecaj_0278)
Accession : YP_302923.1
Strain : Ehrlichia canis Jake
Genome accession: NC_007354
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 423245 - 424942 bp
Length : 1698 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGATTTTATATAATATTTTTCTAGTAAAAATGAAAGTAGACTTTATTAATACCGTATTTCCTTCTTCAACTAAAGAATA
CATTCCAGGTACAATTTACAACAATATCAAAGTAGGAATGCGTAAGATCCACTTTAATGATAATACTGAATCAATACTAG
TATATGATACTGGTGGATTACATACAGATCAAAACGTTGAAGTTGACATTAACCATGGTATTACAAAGTTAAGGCTCAAT
TGGATTATAGATAGACAAGACGTAGAATATTATGAGAGGCAACCAGTTTTAAACTCAGAGCATATATTCACATCACAAAG
CAATAAAGTTTTAAGAGCAAACAGTACTAAACCAGTAACTCAGATTTTTTACGCAAGAAATAATATTATTACTCCAGAAA
TGGAATATATAGCAATAAGAGAAAATTCATTAAGACAGAAAATCCTTTCTTATAAACCAACTGTTATGAGCCCAGAAATT
ACTCCAGAATTTGTACGACAAGAAGTAGCATCTGGTAGAGCAATCATTCCAGCAAATATAAATCATCCTGAATCAGAACC
GATGATCATAGGTAAAAATTTCTTAGTAAAAATCAATGCTAACATTGGTAATTCAGTAGTTAGTTCAAATATTGAAGAAG
AAGTTCAAAAAATGATCCATGCAATTACATATGGTGCAGACACAGTAATGGATTTATCTACAGGAAATAACATACATGAC
ATCCGAGAATGGATTATTAGAAATAGTCCAGTACCAATAGGAACTGTACCTATATATCAAGCCTTAAATAAGGTAAATGG
TGTAGTGGGAGATTTAAATTTTAACGTTTTTAAAGAAACATTAATAGAGCAAGCAGAACAAGGTGTTGATTATTTTACAA
TACATGCAGGAGTATTAAAAAATTACATCAGCCATACAGATAATAGGCTTACTGGTATTGTATCAAGGGGTGGAGCTATT
ATGGCACATTGGTGTACCATACATAATAAGGAAAATTTCCTTTATACAAATTTCGAGGAAATATGTGACATTATGAAACG
CTATGACATTGCTTTCTCATTAGGAGATGGGTTAAGACCAGGATCAATAGCAGATGCAAATGATACAGCACAATTTTTAG
AACTCAAGACATTAGGTGAACTGACAGATATTGCATGGCAACATGATTGTCAAGCTATGATAGAGGGTCCAGGACATGTA
CCTATGCACCTAATAAAAGAGAATATGGAAAAACAAATTCACTTTTGTAAAGAAGCACCATTTTACACATTAGGTCCACT
GACTACAGATATTGCACCAGGTTATGATCACATAACAAGTGCAATAGGTGCAGCAATTACAGGCTGGTATGGGACTTCTA
TGCTATGTTATGTTACACCAAAAGAACACTTAGGATTACCTAATATTCAAGATGTAAAAGACGGAGTTATTGCATATAAG
ATAGCAGCACATGCAGCAGACCTAGCAAAAGGAAACCCATCTGCTTATATACGTGATTATGCACTAAGTTACGCAAGGTT
TAACTTTAAATGGCACGATCAATTCAACTTATCTCTTGATCCAGAAACAGCAAGATCTTTACACGACGAATCTCTACCAT
CTGAGCACGCAAAATCTGCTCATTTCTGTTCAATGTGTGGCCCAAAATTTTGCTCAATGAAACTAACACATCATTTAAAA
GAACATTCTACTGGATAA

Protein sequence :
MILYNIFLVKMKVDFINTVFPSSTKEYIPGTIYNNIKVGMRKIHFNDNTESILVYDTGGLHTDQNVEVDINHGITKLRLN
WIIDRQDVEYYERQPVLNSEHIFTSQSNKVLRANSTKPVTQIFYARNNIITPEMEYIAIRENSLRQKILSYKPTVMSPEI
TPEFVRQEVASGRAIIPANINHPESEPMIIGKNFLVKINANIGNSVVSSNIEEEVQKMIHAITYGADTVMDLSTGNNIHD
IREWIIRNSPVPIGTVPIYQALNKVNGVVGDLNFNVFKETLIEQAEQGVDYFTIHAGVLKNYISHTDNRLTGIVSRGGAI
MAHWCTIHNKENFLYTNFEEICDIMKRYDIAFSLGDGLRPGSIADANDTAQFLELKTLGELTDIAWQHDCQAMIEGPGHV
PMHLIKENMEKQIHFCKEAPFYTLGPLTTDIAPGYDHITSAIGAAITGWYGTSMLCYVTPKEHLGLPNIQDVKDGVIAYK
IAAHAADLAKGNPSAYIRDYALSYARFNFKWHDQFNLSLDPETARSLHDESLPSEHAKSAHFCSMCGPKFCSMKLTHHLK
EHSTG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 65
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 65
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-167 60